What is the role of antibody tests in lupus diagnosis?

Antibody tests play a crucial role in lupus diagnosis. The presence of specific antibodies, such as antinuclear antibodies (ANA), anti-DsDNA, anti-Smith (Sm), anti-Ro (SSA), and anti-La (SSB), can indicate an autoimmune response. These tests help confirm lupus diagnosis, distinguish it from other conditions, and assist in monitoring disease activity.