Cirrhosis Diagnosis and Screening: 5 Accurate Tests for Liver

Cirrhosis Diagnosis and Screening: 5 Accurate Tests for Liver

Cirrhosis is a serious liver condition that can lead to life-threatening complications, making early cirrhosis diagnosis and treatment crucial for better outcomes.

 

5 Tests for Cirrhosis Diagnosis

Here are some common tests used in the cirrhosis diagnosis:

  1. Liver function tests (LFTs)
  2. Complete blood count (CBC)
  3. Blood ammonia levels
  4. Liver biopsy
  5. Alpha-fetoprotein (AFP)

 

Cirrhosis Test - Drlogy

 

1. Liver Function Tests (LFTs)

  • This cirrhosis test measures levels of liver enzymes and proteins.
  • They assess liver function and detect liver damage.
  • LFTs include tests like ALT, AST, and bilirubin.
Liver Function Tests (LFTs) Details
Also Known As Liver panel
Purpose Assess liver function and health
Sample Blood
Preparation Fasting for 8-12 hours
Procedure Blood draw from a vein
Test Timing A few hours
Test Price (INR) 500-2000
Result Value Various liver enzyme levels, bilirubin, albumin, etc.
Normal Value Varies with different parameters
Accuracy High accuracy
Interpretation Abnormal values may indicate liver damage, disease, or dysfunction

Liver Function Tests (LFTs) assess liver function and health through blood tests, measuring enzyme levels and other parameters for cirrhosis diagnosis.

 

2. Complete Blood Count (CBC)

  • This cirrhosis test measures the number of red blood cells in a given volume of blood.
  • Measures the amount of oxygen-carrying protein in the blood.
  • Determines the number of platelets involved in blood clotting.
Complete Blood Count (CBC) Details
Also Known As Blood count
Purpose Evaluate overall blood health and detect abnormalities
Sample Blood
Preparation None
Procedure Blood draw from a vein
Test Timing 2-4 hours
Test Price (INR) 200-1000
Result Value Red blood cells, white blood cells, hemoglobin, platelets, etc.
Normal Value Varies with different parameters
Accuracy High accuracy
Interpretation Abnormalities may indicate infection, anemia, or other blood disorders

Complete Blood Count (CBC) evaluates overall blood health, including red and white blood cells, hemoglobin, and platelets. It detects abnormalities, aiding in the cirrhosis diagnosis of infections, anemia, and blood disorders.

 

3. Blood Ammonia Levels

  • This cirrhosis test elevated blood ammonia levels indicating liver dysfunction.
  • High ammonia levels can lead to neurological symptoms.
  • Monitoring blood ammonia levels is crucial in managing cirrhosis.
Blood Ammonia Levels Details
Also Known As Ammonia test
Purpose Assess liver function and ammonia metabolism
Sample Blood
Preparation Fasting for 8-12 hours
Procedure Blood draw from a vein
Test Timing A few hours
Test Price (INR) 500-1500
Result Value Ammonia concentration in blood
Normal Value 15-45 micrograms/dL
Accuracy High accuracy
Interpretation Elevated levels indicate liver dysfunction or impaired ammonia metabolism

Blood ammonia levels of cirrhosis test measures ammonia concentration in blood, helping assess liver function and detecting abnormalities related to ammonia metabolism.

 

4. Liver Biopsy

  • A small piece of liver tissue is taken for analysis.
  • This cirrhosis test, helps to determine the cause, severity, and stage of liver disease.
  • May include bleeding, infection, or injury to nearby organs.
Liver Biopsy Details
Also Known As Hepatic biopsy
Purpose Obtain liver tissue sample for analysis
Sample Liver tissue
Preparation Fasting for 8-12 hours
Procedure Insertion of a needle or a small incision
Test Timing A few days
Test Price (INR) 5,000-10,000
Result Value Examination of liver tissue for signs of inflammation, fibrosis, cirrhosis
Normal Value Absence of significant abnormalities
Accuracy Highly accurate for diagnosing liver conditions
Interpretation Helps determine the cause, stage, and severity of liver diseases

Liver biopsy is a procedure to obtain liver tissue for analysis. It helps diagnose liver conditions by examining tissue for inflammation, fibrosis, cirrhosis, or cancer, providing valuable insights into the cause and severity of liver diseases.

 

5. Alpha-Fetoprotein (AFP)

  • Tumor marker for liver cancer.
  • Elevated levels may indicate liver damage or cancer.
  • This cirrhosis test is used in the surveillance and monitoring of cirrhosis patients.
Alpha-fetoprotein (AFP) Details
Also Known As AFP tumor marker
Purpose Detect and monitor liver cancer
Sample Blood
Preparation None
Procedure Blood draw from a vein
Test Timing A few hours
Test Price (INR) 500-1500
Result Value AFP concentration in blood
Normal Value <10 ng/mL
Accuracy Varies, not diagnostic
Interpretation Elevated levels may indicate liver cancer, but further testing is required

Alpha-fetoprotein (AFP) is a blood test used to detect and monitor liver cancer. Elevated levels may indicate liver cancer, but further testing is needed for confirmation.

 

Cirrhosis Diagnosis Tests Overview

Test Name Liver Function Tests (LFTs) Complete Blood Count (CBC) Blood Ammonia Levels
Also Known As Liver panel Blood count Ammonia test
Purpose Assess liver function and health Evaluate overall blood health and detect abnormalities Assess liver function and ammonia metabolism
Sample Blood Blood Blood
Preparation Fasting for 8-12 hours None Fasting for 8-12 hours
Procedure Blood draw from a vein Blood draw from a vein Blood draw from a vein
Test Timing A few hours 2-4 hours A few hours
Test Price (INR) 500-2000 200-1000 500-1500
Result Value Various liver enzyme levels, bilirubin, albumin, etc. Red blood cells, white blood cells, hemoglobin, platelets, etc. Ammonia concentration in blood
Normal Value Varies Varies 15-45 micrograms/dL
Accuracy High accuracy High accuracy High accuracy
Interpretation Abnormal values may indicate liver damage, disease, or dysfunction Abnormalities may indicate infection, anemia, or other blood disorders Elevated levels indicate liver dysfunction or impaired ammonia metabolism

*Test Price, range, and timing may vary as per location, lab type, and procedure.

Liver Function Tests (LFTs), Complete Blood Count (CBC), and Blood Ammonia Levels are crucial tests to assess liver function, overall blood health, and ammonia metabolism. These tests help in cirrhosis diagnosis liver disorders, detect abnormalities, and guide appropriate medical interventions.

 

Cirrhosis Differential Diagnosis

Similar Diseases Differentiating Factors
Non-alcoholic fatty liver disease (NAFLD) History of alcohol abuse, liver biopsy findings
Hepatitis C Viral serology, liver enzyme levels
Alcoholic hepatitis History of alcohol abuse, liver enzyme levels
Autoimmune hepatitis Autoimmune serology, liver enzyme levels
Primary biliary cholangitis (PBC) Autoimmune serology, presence of anti-mitochondrial antibodies
Wilson's disease Copper metabolism studies, genetic testing
Hemochromatosis Iron studies, genetic testing

Differential cirrhosis diagnosis includes non-alcoholic fatty liver disease, hepatitis C, alcoholic hepatitis, autoimmune hepatitis, primary biliary cholangitis, Wilson's disease, and hemochromatosis, each with unique differentiating factors based on history, serology, and specialized tests.

 

Best Doctor for Cirrhosis

Specialist Description
Hepatologist Liver disease specialist
Gastroenterologist Digestive system specialist
Hepatobiliary Surgeon Surgical specialist for liver diseases
Interventional Radiologist Performs minimally invasive procedures for liver disorders
Transplant Hepatologist Specializes in liver transplantation and management of post-transplant patients

One of the best doctors for cirrhosis is a Hepatologist, a specialist in liver diseases and their treatment.

 

7 Interesting Facts of  Cirrhosis Diagnosis

  1. Cirrhosis diagnosis can be done through imaging tests like ultrasound and MRI.
  2. A liver biopsy is the gold standard for cirrhosis diagnosis.
  3. Blood tests can measure liver enzyme levels and assess liver function.
  4. Advanced imaging techniques like transient elastography can determine liver stiffness.
  5. Non-invasive methods like FibroScan can provide accurate liver fibrosis assessment.
  6. Genetic testing can identify inherited liver conditions contributing to cirrhosis.
  7. Cirrhosis diagnosis often involves evaluating symptoms, medical history, and risk factors.

 

Conclusion

Cirrhosis diagnosis involves a medical history, physical exam, imaging, and blood tests, with a liver biopsy considered the gold standard. Early detection and treatment are crucial.

 

Reference

  • Cirrhosis Diagnosis and Test [1].
  • Diagnosis of Cirrhosis - NIDDK [2].

 

favorite_border 666 Likes

INDIA’S MOST TRUSTED HEALTHCARE PLATFORM

10M+

Patients

22000+

Doctors

20000+

Hospitals/Labs

Drlogy®
The Power To Health

Copyright © 2024 Drlogy. All rights reserved.