Tacrolimus Test For Organ Transplant

Tacrolimus Test For Organ Transplant

The Tacrolimus Test is a blood test to check drug levels after organ transplant. It helps to ensure the medication is working properly and safe for patients.

 

Tacrolimus Test

Here are the basic details of the Tacrolimus Test.

Also Known As Tacrolimus Level Test
Type Blood Test
Purpose Measures the concentration of Tacrolimus in the blood
Sample Type Whole blood
Preparation No
Fasting Not required
Gender Unisex
Age Group All
Normal Value 5-15 ng/ml
Reporting Time A few days
Cost 3000-4000 INR*

*Tacrolimus Test Price range may vary as per location, lab type, and lab test procedure.

 

Tacrolimus Test Means

  • Tacrolimus Test assesses drug levels after organ transplants. Ensures drug efficacy and patient safety post-surgery.
  • For the Tacrolimus Test, a blood sample is needed. No fasting is typically required, suitable for all genders and ages.
  • It helps optimize Tacrolimus Test medication, preventing organ rejection. Results are usually available in a few days.
  • The cost for Tacrolimus Test varies. Contact the testing facility for specific pricing in Indian Rupees (INR).
  • Reference values differ, but it's typically 10-12 ng/ml for certain post-transplant periods.

 

Tacrolimus Test Purpose

The purpose of the Tacrolimus Test is to:

  • Tacrolimus Test ensures the drug's right dosage after transplantation, vital for post-surgery safety.
  • It monitors and maintains Tacrolimus Test medication levels, preventing organ rejection.
  • This test assesses blood levels of Tacrolimus to optimize the drug's efficacy.
  • Applicable to all genders and ages, the Tacrolimus Test plays a crucial role in transplant care.

Tacrolimus Test- Price, Normal Range, Result, Purpose, Procedure Meaning and Interpretation - Drlogy Test

 

Tacrolimus Test Preparation

Here is the basic preparation for the Tacrolimus Test.

 

Before Test

  • No specific dietary restrictions, but follow your healthcare provider's guidance.
  • Take medications as prescribed.
  • Inform your healthcare provider about any changes in your medical history.

 

During Test

  • A blood sample is collected, usually from the arm.
  • Stay relaxed during the procedure.
  • Follow all instructions provided by the healthcare provider.

 

After Test

  • Continue with your medication and follow your transplant team's advice.
  • Await test results to monitor Tacrolimus levels.
  • Discuss results and any necessary medication adjustments with your healthcare provider.

 

Tacrolimus Test Procedure

Here is the basic Tacrolimus Test Procedure.

  • Blood sample collected from the arm vein.
  • Sample processed in the lab.
  • Tacrolimus levels measured and reported.

 

Tacrolimus Test Result

Here is the basic reading of the Tacrolimus Test results.

  • Within range: Indicates effective immune suppression.
  • Below range: Suggests potential organ rejection risk.
  • Above range: Raises concerns about toxicity and kidney damage.

 

Tacrolimus Test Normal Result Report

TACROLIMUS Test Normal Result Report Format - Drlogy test

Tacrolimus Test Normal Report

Tacrolimus Test Normal Result Report PDF

 

Tacrolimus Test Abnormal Result Report

TACROLIMUS Test Abnormal Result Report Format - Drlogy Test

Tacrolimus Test Abormal Report

Tacrolimus Test Abnormal Result Report PDF

 

Tacrolimus Test Normal Range

Here is the normal range of the Tacrolimus Test.

Test Normal Range
Tacrolimus Test 5 - 15 ng/ml

 

Tacrolimus Test Interpretation

Here is the Interpretation of the Tacrolimus Test.

Tacrolimus Level (ng/ml) Interpretation
Below 5 High risk of organ rejection, further evaluation is needed.
5 to 15 Within the normal therapeutic range, ideal for immune suppression.
Above 15, particularly above 20 Suggests potential toxicity, may lead to kidney failure or other complications.

Tacrolimus levels below 5 ng/ml signal organ rejection risk, 5-15 ng/ml is the therapeutic range, above 15 ng/ml indicates potential toxicity.

 

Tacrolimus Test High Levels

Here are the potential causes of high Tacrolimus Test levels:

Possible Causes Description
Overdose or Medication Error Excessive intake or dosing errors may result in high Tacrolimus levels.
Impaired Metabolism Certain drug interactions can impair Tacrolimus metabolism.
Reduced Excretion Kidney dysfunction can lead to decreased excretion of Tacrolimus.
Drug Interactions Concurrent use of medications that affect Tacrolimus metabolism.
Non-Adherence Not taking the medication as prescribed.

High Tacrolimus levels may be due to overdose, impaired metabolism, reduced excretion, drug interactions, or non-adherence to medication.

 

Tacrolimus Test Low Levels

Here are the potential causes of low Tacrolimus Test levels:

Possible Causes Description
Underdosing Insufficient medication intake or dosage.
Rapid Metabolism Some individuals metabolize Tacrolimus quickly.
Enzyme Induction Certain drugs can induce enzymes that break down Tacrolimus faster.
Drug Interactions Concurrent use of medications that interact with Tacrolimus.

Low Tacrolimus levels can be caused by underdosing, rapid metabolism, enzyme induction, drug interactions or medication.

 

Specimen Requirements For Tacrolimus Test

Here are the specimen requirements for the Tacrolimus Test.

Specimen

Whole blood

Volume

1 mL

Container

Lavender-top (EDTA) tube

Storage Instruction

Room temperature

Causes for Rejection

Plasma or serum specimen

 

Tacrolimus Test is Safe?

The Tacrolimus Test is generally safe for patients.

  • It helps monitor medication levels and organ transplant success.
  • The test itself poses minimal risk, typically involving a blood sample.
  • Safety depends on appropriate medication use guided by test results.
  • Discuss safety concerns with a healthcare provider.

 

When Do You Get Tacrolimus Test Results? 

  • Typically available within a few days.
  • Time can vary depending on the laboratory and location.
  • The healthcare provider will communicate the results to the patient.
  • Results are crucial for monitoring organ transplant recipients.
  • Faster turnaround may be possible in urgent cases.

 

Tacrolimus Test Limitation

Here is the basic limitation of the Tacrolimus Test.

  • Test measures Tacrolimus concentration, not its effectiveness.
  • Individual responses to Tacrolimus vary; levels may not correlate with outcomes.
  • Other factors, like drug interactions and kidney function, influence Tacrolimus effects.
  • Variability in test methods and reference ranges across labs.
  • Interpretation should consider clinical context and patient-specific factors.

 

Tacrolimus Test Risk Factors

Here are some of the risk factors of the Tacrolimus Test.

  • Incorrect medication dosing or non-adherence.
  • Drug interactions affecting Tacrolimus metabolism.
  • Impaired kidney function or Rapid Tacrolimus metabolism.
  • Underlying medical conditions impacting drug levels.

 

Doctor Recommendations After Tacrolimus Test Result

 Here are the Doctor's recommendations or consult a specialist after the Tacrolimus Test.

Test Result Doctor to Visit Reason
High Transplant Specialist Potential overdose or drug interactions.
Normal Transplant Specialist Ideal drug levels and organ function.
Low Transplant Specialist Potential non-adherence or rapid metabolism.

 

Tacrolimus Test Price

Here are the estimated Tacrolimus Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

3000-4000

New Delhi

3000-4000

Bangalore

3000-4000

Hyderabad

3000-4000

Kolkata

3000-4000

Pune

3000-4000

Lucknow

3000-4000

Noida

3000-4000

Surat

3000-4000

Gurugram

3000-4000

Patna

3000-4000

Chennai

3000-4000

Jaipur

3000-4000

Ahmedabad

3000-4000

*Tacrolimus Test Price are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall, The Tacrolimus Test assesses drug levels post-transplant; high levels indicate risk of overdose, low levels may suggest non-adherence. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • Tacrolimus - Wikipedia [1].
  • Tacrolimus - StatPearls NIH [2].

 

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Tacrolimus Test FAQ

What is a tacrolimus blood test for?

A tacrolimus blood test is used to monitor the drug levels in a patient's bloodstream to ensure it's within a therapeutic range, especially after organ transplantation.

What is the principle of tacrolimus test?

The test measures the concentration of tacrolimus in the blood using immunoassays or mass spectrometry, providing insights into drug efficacy and potential toxicity.

What are the methods of tacrolimus test?

The methods include immunoassays (e.g., enzyme-linked immunosorbent assay) and mass spectrometry (e.g., LC-MS/MS), offering varying levels of precision and sensitivity.

What is a normal tacrolimus level?

Normal levels vary by transplant type, but therapeutic ranges typically aim for 5-15 ng/mL in the first few months and 3-10 ng/mL later for kidney transplant recipients.

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