International Normalised Ratio (INR) Test For Blood Clotting

International Normalised Ratio (INR) Test For Blood Clotting

The International Normalised Ratio (INR) Test is a blood test that measures how well the blood clots are by assessing the time it takes for blood to coagulate. It's commonly used to monitor the effectiveness of blood-thinning medications, such as warfarin, and ensure safe anticoagulant therapy.

 

INR Test

Here are the basic details of the INR Test.

Also Known As Prothrombin Time
Type Blood Test
Purpose Blood Clotting Evaluation
Sample Type Blood
Preparation None
Fasting Not Required
Gender Any
Age Group Any
Normal Value 0.8 - 1.2
Reporting Time Within 24 hours
Cost 150-300 INR*

*INR Test Price range may vary as per location, lab type, and lab test procedure.

 

INR Test Means

INR is a standardized measure of blood clotting ability.

  • The INR test is essential for monitoring patients on anticoagulant medications, such as warfarin.
  • It ensures that blood clotting remains within a safe therapeutic range to prevent clots or excessive bleeding.
  • The test helps guide the dosing of anticoagulants and reduces the risk of complications.
  • INR results are crucial for individuals with atrial fibrillation, deep vein thrombosis, and heart valve disorders.
  • Regular INR testing is necessary for patients on long-term anticoagulant therapy.

 

INR Test Purpose

The purpose of the INR Test is to:

  • To monitor blood clotting ability in patients on anticoagulant medications, such as warfarin.
  • Ensure blood clotting remains within a safe therapeutic range to prevent clots or excessive bleeding.
  • Guide anticoagulant dosing to reduce the risk of complications.
  • Manage and prevent conditions like atrial fibrillation, deep vein thrombosis, and heart valve disorders.
  • Facilitate ongoing monitoring and adjustments of anticoagulant therapy.
  • Improve patient safety and optimize anticoagulant treatment outcomes.

International Normalised Ratio INR Test - Price, Normal Range, Result, Purpose, Procedure Meaning and Interpretation- Drlogy Test

 

INR Test Preparation

Here is the basic preparation for the INR Test.

 

Before Test

  • No specific dietary or fasting requirements.
  • Ensure you inform your healthcare provider of any medications you are taking, especially blood-thinning medications like warfarin.

 

During Test

  • A blood sample is collected to measure your INR.

 

After Test

  • Resume normal activities.
  • Wait for your healthcare provider to provide you with your INR results.

 

INR Test Procedure

Here is the basic INR Test Procedure.

  • A blood sample is collected from a vein in your arm.
  • The sample is processed to measure your clotting time and calculate the INR.
  • Results are typically available on the same day.
  • Your healthcare provider will discuss the results with you, especially if you are on anticoagulant medication.
  • Medication dosages may be adjusted based on the INR results.
  • Regular monitoring may be required if you are on anticoagulation therapy.

 

INR Test Result

Here is the basic reading of INR Test results.

  • Target Range: The desired INR range varies depending on the medical condition and the prescribed anticoagulant.
  • INR Value: The result indicates how long it takes for your blood to clot relative to the control sample.
  • Therapeutic Range: Results within or close to the target range suggest effective anticoagulant therapy.
  • Dosing Adjustments: INR results guide adjustments to anticoagulant medication doses for blood clotting control.

 

INR Test Normal Range

Here is the normal range of the INR Test

Category INR Range
Not on Anticoagulant Medications 0.8 - 1.1
On Anticoagulant Medications (e.g., Warfarin) 2.0 - 3.5

 

INR Test Interpretation

Here is the Interpretation of the INR Test.

INR Level Interpretation
Below 0.8 High risk of dangerous blood clots.
0.8 - 1.1 Normal range (for individuals not on anticoagulant medications).
Above 1.1 Slower blood clotting; potential need for dose adjustment.
2.0 - 3.5 Target range for individuals on anticoagulant medications (e.g., Warfarin).
Above 3.5 High risk of dangerous bleeding.

 

INR Test High Levels

Here are the potential causes of high INR Test levels:

Potential Causes Explanation
Excessive anticoagulant dosage Overuse or overdose of anticoagulant medications, such as Warfarin.
Drug interactions Interactions with medications or supplements that affect anticoagulation.
Liver dysfunction Impaired liver function can affect the metabolism of clotting factors.
Vitamin K deficiency Inadequate vitamin K intake affecting clotting factors.
Severe bleeding or hemorrhage Rapid depletion of clotting factors from excessive bleeding.

 

INR Test Low Levels

Here are the potential causes of low INR Test levels:

Potential Causes Explanation
Insufficient anticoagulant dosage Underuse or insufficient dose of anticoagulant medications.
Changes in diet Consuming foods high in vitamin K, can reduce anticoagulant effectiveness.
Medication interactions Interactions with medications that reduce anticoagulant effects.
Clotting disorder or factor excess Conditions or factors promoting excessive clotting.
Coagulation factor abnormalities Genetic or acquired deficiencies in clotting factors.

 

Specimen Requirements For INR Test

Here are the specimen requirements for the INR Test.

Specimen

Serum

Volume

1 ml

Container

Red-top tube or gel-barrier tube

Collection

Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.

Storage

Refrigerate or freeze.

Sample Stability

Temperature

Period

Room temperature

7 day

Refrigerated

14 days

Frozen

60 days

Freeze/thaw cycles

Stable x1

Causes for Rejection

Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types

 

INR Test is Safe?

INR tests are safe and commonly used to monitor blood clotting for individuals on anticoagulant therapy.

  • The test involves a standard blood draw and is well-tolerated by patients.
  • Regular INR testing is essential for safe and effective anticoagulation management.

 

When Do You Get INR Test Results? 

  • INR test results are often available within 24 hrs of the test.
  • Your healthcare provider will discuss the results and any necessary adjustments to anticoagulant medication during the same or a subsequent appointment.

 

INR Test Limitation

Here is the basic limitation of the INR Test.

  • INR measures the clotting ability of blood but may not reflect all factors influencing bleeding risk.
  • Differences in reagents and equipment can lead to varying INR results.
  • INR levels may not account for individual variations in response to anticoagulants.
  • Monitoring should consider clinical context, and decisions should not rely solely on INR.
  • INR may not accurately assess bleeding risk in specific conditions, such as liver disease.

 

INR Test Risk Factors

Here are some of the risk factors of the INR Test.

  • Taking anticoagulant medications, such as warfarin or heparin.
  • Underlying medical conditions that increase the risk of blood clots, such as atrial fibrillation or deep vein thrombosis.
  • Frequent changes in diet or medications that can affect INR levels.
  • Liver disease, which can impact the body's ability to process vitamin K.
  • Genetic factors that affect the metabolism of anticoagulants.

 

Doctor Recommendations After INR Test Result

 Here are the Doctor's recommendations or consult a specialist after the INR Test.

INR Level Doctor to Visit Reason to Go to Doctor
High Hematologist Risk of bleeding, medication adjustment.
Normal Primary Care Physician Routine monitoring and healthcare.
Low Hematologist or Primary Care Risk of clotting, medication adjustment.

 

INR Test Price

Here are the estimated INR Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

150-300

New Delhi

200-300

Bangalore

150-300

Hyderabad

200-300

Kolkata

150-300

Pune

200-300

Lucknow

150-300

Noida

200-300

Surat

200-300

Gurugram

150-300

Patna

200-300

Chennai

150-300

Jaipur

200-300

Ahmedabad

150-300

*INR Test Price are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall, INR Test is critical for individuals on anticoagulant therapy, ensuring that blood clotting remains in the therapeutic range, preventing both bleeding and clotting complications. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • INR - Wikipedia [1].
  • International Normalized Ratio (INR) - StatPearls NIH [2].
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INR Test FAQ

What does an INR of 1.5 mean?

An INR of 1.5 indicates a slightly increased risk of bleeding. It suggests that blood takes 1.5 times longer to clot than the average.

What is a normal PT INR level?

The normal PT INR level is around 1.0 for individuals not on blood-thinning medication.

What happens if INR is high?

High INR indicates increased risk of bleeding. Excessive anticoagulation may lead to hemorrhage.

What is INR in liver function test?

INR (International Normalized Ratio) in liver function tests measures blood clotting ability. Elevated levels may indicate liver dysfunction.

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