VDRL Test For Sexually Transmitted Disease

VDRL Test For Sexually Transmitted Disease

The VDRL (Venereal Disease Research Laboratory) test is a blood test that is used to screen for syphilis, a sexually transmitted disease caused by the bacterium Treponema pallidum. It is not specific to a particular gender and can be used as a screening tool for syphilis infection in both males and females. VDRL test in pregnancy is also performed for infection.



Here are the basic details for VDRL Test.

Also Known As Venereal Disease Research Laboratory Test
Type Blood Test
Diagnose Syphilis a sexually transmitted infection
Sample Type Blood serum
Preparation No Special Preparation Required
Fasting No
Gender Unisex
Age-Group All Ages
Normal Value A positive test indicates the presence of Antibodies
Reporting Time 1 - 2 hours
Cost (INR) 100 - 300* INR

*Price range may vary as per location, lab type, and procedure of lab test.


VDRL Test Full Form

The Full Form For VDRL Test is Venereal Disease Research Laboratory Test.


VDRL Test Means

VDRL Test is a blood test used to screen for syphilis.

  • VDRL Test detects the presence of antibodies produced in response to the syphilis bacteria.
  • A positive VDRL test indicates the presence of syphilis infection.
  • It is an initial screening test and further confirmatory tests are needed for a definitive diagnosis.
  • VDRL Test in pregnancy is also commonly performed to screen for syphilis infection in expectant mothers, as untreated syphilis can pose serious health risks to both the mother and the baby.


VDRL Test Purpose

Here are the purposes of the VDRL Test.

  • The VDRL test is commonly used to diagnose syphilis, a sexually transmitted infection caused by the bacterium Treponema pallidum.
  • The VDRL test is also used as a screening tool to detect syphilis in people who may not have any symptoms but are at risk of infection.
  • It can be used to monitor the effectiveness of treatment for syphilis. A decrease in the titer (level) of antibodies in the blood indicates that treatment is working.
  • If the VDRL test is positive, a confirmatory test such as the Treponemal Pallidum Antibody (TP-PA) test is usually done to confirm the diagnosis of syphilis.
  • The VDRL test may be used to test for other conditions that can cause false positive results on a syphilis test, such as lupus and rheumatoid arthritis.


VDRL Test Price Normal Range Results Purpose Meaning and Interpretation - Drlogy Test


VDRL Test Preparation

Here are some preparations, procedures, and aftercare for the VDRL test:


Before Test

  • No fasting or other special preparations are required before the test.
  • Inform your doctor about any medications or supplements you are taking, as some can affect the test results.
  • Inform your doctor if you have any allergies or blood clotting disorders.


During Test

  • The VDRL test involves drawing a blood sample from a vein in your arm.
  • The test is usually done in a doctor's office or laboratory by a trained healthcare professional.
  • The blood sample is sent to a lab for analysis.


After Test

  • The VDRL test usually takes a few days to process.
  • Your doctor will inform you of the results and what they mean for your health.
  • If the test is positive, your doctor may recommend additional tests to confirm the diagnosis and begin treatment.
  • If you test negative but have symptoms of syphilis, your doctor may recommend further testing or monitoring.


The VDRL Test requires a blood sample and may require additional testing for diagnosis or treatment if positive.


VDRL Test Procedure

Here is the procedure for the VDRL test:

  • A healthcare professional will clean the area where the blood will be drawn, usually the inner elbow or back of the hand, with an antiseptic solution.
  • A tourniquet will be tied around your upper arm to help locate a vein and make it easier to draw blood.
  • A needle will be inserted into the vein, and a small amount of blood will be drawn into a sterile tube.
  • After the needle is removed, a cotton ball or bandage will be placed over the site to stop any bleeding.
  • The blood sample will be sent to a laboratory for analysis.
  • The results of the VDRL test will be provided to you by your healthcare provider.


VDRL Test Result

Here are some key points regarding VDRL test results:

  • A non-reactive or negative VDRL test result means that no syphilis antibodies were detected in your blood.
  • A reactive or positive VDRL test result means that syphilis antibodies were detected in your blood.
  • A reactive VDRL test may indicate a current or past infection with syphilis. However, false positive results are possible, and additional tests are needed to confirm a diagnosis.
  • If your VDRL test is positive, your healthcare provider will recommend additional tests to confirm the diagnosis and begin treatment if necessary.
  • If you have a history of syphilis or have been treated for syphilis, a VDRL test may remain positive even if you are no longer infected.


VDRL Test Report

VDRL Test Report - Drlogy Test

VDRL Test Report PDF


VDRL Test Interpretation

The VDRL test does not have a specific normal range. However, here is some information about the interpretation of the test results.

VDRL Test Result Interpretation
Non-reactive or negative No syphilis antibodies detected
Reactive or positive Syphilis antibodies detected
False positive Positive results due to other medical conditions, such as autoimmune diseases, pregnancy, or recent vaccinations

It is important to note that a positive VDRL test does not necessarily mean that you have an active syphilis infection. Additional VDRL Test in pregnancy tests are needed to confirm a diagnosis and false positive results can occur.


VDRL Test Positive Means

Here is a possible cause of VDRL Test positive means.

Positive Result Means Possible Causes
Presence of syphilis antibodies Syphilis infection
False-positive result Other infections (e.g., HIV, hepatitis), autoimmune diseases
Previous syphilis infection Successfully treated or inactive syphilis infection


A Positive VDRL Test indicates the presence of syphilis infection or other possible causes.


VDRL Test is Safe?

  • VDRL test is a safe and routine screening test for syphilis.
  • It involves a simple blood draw and does not pose any significant risks or side effects.
  • However, false-positive results can occur, which may require additional testing to confirm the diagnosis.


When Do You Get VDRL Test Results?

  • The turnaround time for VDRL test results varies depending on the laboratory where the test was performed and the method used.
  • In general, results may be available within 1-2 hours after the sample is collected.
  • Your healthcare provider will be able to provide you with more information about when you can expect to receive your VDRL test results.


VDRL Test Limitation

Here are some possible limitations of the VDRL Test.

  • False-negative results in the early stages of syphilis.
  • Limited specificity, leads to false-positive results in certain conditions.
  • Cannot differentiate between active and past syphilis infection.
  • Requires confirmation with additional tests for accurate diagnosis.
  • May not detect syphilis in certain body fluids or tissues.


VDRL Test Risk Factors

Here is the potential risk factor of the VDRL Test.

  • High-risk sexual behavior, such as multiple sexual partners.
  • Unprotected sexual intercourse with an infected individual.
  • History of previous sexually transmitted infections (STIs).
  • Intravenous drug use and sharing needles.
  • VDRL test in pregnancy for Vertical transmission from mother to child during pregnancy or childbirth.


Doctor Recommendations After VDRL Test Result

Here are Doctor recommendations or consult a specialist after VDRL Test.

VDRL Test Result Doctor to Visit Reason to Visit
High Infectious Disease Possible syphilis infection
Normal General Practitioner Routine follow-up or other symptoms
Low No specific doctor No immediate concerns


VDRL Test Price

Here are the estimated VDRL Test Price in India with different top cities.

City Price Range (INR)*
Mumbai 100 - 300
New Delhi 150 - 300
Bangalore 150 - 300
Hyderabad 100 - 300
Kolkata 150 - 300
Pune 150 - 300
Lucknow 100 - 300
Noida 100 - 300
Surat 150 - 300
Gurugram 100 - 300
Patna 150 - 300
Chennai 100 - 300
Jaipur 150 - 300
Ahmedabad 100 - 300

*Prices are approximate and vary depending on a specific laboratory or healthcare facility.



Overall, VDRL Test is a blood test used to diagnose syphilis and to monitor the effectiveness of treatment; it measures the antibodies that the body produces in response to the bacterium that causes syphilis. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.



  • Venereal Disease Research Laboratory test - Wikipedia [1].
  • Syphilis- Wikipedia [2].



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What is a VDRL Test?

  • The VDRL (Venereal Disease Research Laboratory) test is a blood test used to screen for syphilis, a sexually transmitted infection caused by the bacterium Treponema pallidum.
  • It detects the presence of antibodies produced by the body in response to a syphilis infection.

Why is a VDRL Test done?

  • The VDRL Test is performed to screen for syphilis in individuals who may have been exposed to the infection.
  • It is commonly included in routine prenatal testing to detect syphilis in pregnant women, as the infection can be transmitted from mother to baby during pregnancy and lead to severe complications.
  • The test is also used for diagnosing and monitoring the treatment of syphilis in individuals with symptoms or known exposure.

How is a VDRL Test performed?

  • The VDRL Test involves a blood sample taken from a vein, usually from the arm.
  • The blood sample is then sent to a laboratory for analysis.
  • In the laboratory, the sample is mixed with a solution containing substances that react with syphilis antibodies. The reaction is observed, and the results are reported as reactive (positive) or non-reactive (negative).

How to interpret the results of a VDRL Test?

A non-reactive (negative) VDRL Test result typically indicates the absence of syphilis antibodies in the blood, suggesting no current infection.

  • However, it's important to note that the test may not detect early-stage or recent infections.
  • Follow-up testing may be necessary if there is a suspicion of recent exposure.
  • A reactive (positive) VDRL Test result indicates the presence of syphilis antibodies in the blood.
  • Further testing, such as confirmatory tests (e.g., treponemal tests) and clinical evaluation, is needed to confirm the diagnosis and determine the stage of the infection.
  • Positive results should be reported to a healthcare provider for appropriate treatment and management.

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