The Coagulation Profile Test is a blood test that evaluates how well your blood can clot. It helps diagnose clotting disorders and guides treatment for conditions like hemophilia and thrombosis.
Coagulation Profile Test
Here are the basic details of the Coagulation Profile Test.
Also Known As |
Coagulation Screen, Blood Coagulation Test |
Type |
Blood test |
Purpose |
Assess blood clotting ability and disorders |
Sample Type |
Blood sample |
Preparation |
No |
Fasting |
No |
Gender |
Unisex |
Age Group |
All |
Normal Value |
Varies by Parameters |
Reporting Time |
Few Hours |
Cost |
2000-3000 INR* |
*Price range may vary as per location, lab type, and procedure of lab test.
Coagulation Profile Test Means
The Coagulation Profile assesses blood clotting ability.
- It measures various clotting factors in the blood.
- Abnormal results can indicate bleeding or clotting disorders.
- Used to diagnose conditions like haemophilia and thrombosis.
- Helps guide treatment and monitor anticoagulant therapy.
Coagulation Profile Test Purpose
The purpose of the Coagulation Profile Test is to:
- Assess the blood's ability to clot properly.
- Diagnose bleeding disorders or excessive clotting disorders.
- Monitor the effectiveness of anticoagulant medications.
- Evaluate liver function and overall blood health.
- Guide treatment decisions for various blood-related conditions.
Coagulation Profile Test Preparation
Here is the basic preparation for the Coagulation Profile Test.
Before Test
- No specific fasting or dietary restrictions are typically required.
- Inform your healthcare provider about all medications and supplements you are taking, as some medications can affect coagulation test results.
- Follow any additional instructions provided by your healthcare provider.
During Test
- Cooperate with the healthcare professional conducting the test.
- A blood sample will be taken, usually from a vein in your arm.
After Test
- Resume normal activities as advised by your healthcare provider.
- You may experience slight discomfort or bruising at the site where the blood was drawn, which is normal and should subside.
- Your healthcare provider will discuss the test results with you and provide guidance based on the findings.
Coagulation Profile Test Procedure
Here's the Coagulation Profile Test Procedure.
- A blood sample is collected from a vein, usually in the arm.
- The blood is collected into a specialized tube that contains an anticoagulant to prevent clotting.
- The sample is sent to a laboratory for analysis.
- In the laboratory, various tests are performed to assess the blood's clotting ability. These tests may include measuring the time it takes for blood to clot (prothrombin time, partial thromboplastin time), assessing the levels of specific clotting factors, and other coagulation-related measurements.
- The results are reported to a healthcare provider for interpretation.
Coagulation Profile Test Result
Here's a concise interpretation of a Coagulation Profile Test result:
- Bleeding Time (BT): Measures how quickly bleeding stops after a cut. Normal: 3 - 10 minutes. Longer times may indicate a bleeding risk.
- Clotting Time (CT): Evaluates blood clotting speed. Normal: 2 - 7 minutes. Deviations could indicate clotting issues.
- Prothrombin Time (PT): Assesses clotting factors and liver function. Abnormal values suggest liver problems, vitamin K deficiency, or anticoagulant use.
- Activated Partial Thromboplastin Time (APTT): Checks clotting factor levels. Deviations from the normal range may signal clotting factor deficiencies or conditions like haemophilia.
Coagulation Profile Test Report
Coagulation Profile Test Report PDF
Coagulation Profile Test Normal Report
Coagulation Profile Normal Test Report PDF Format
Coagulation Profile Test Normal Result Report PDF
Coagulation Profile Test Abnormal Report
Coagulation Profile Abnormal Test Report PDF Format
Coagulation Profile Test Abnormal Result Report PDF
Coagulation Profile Test Normal Range
Here are the normal ranges of the coagulation profile test.
Parameters |
Normal Range Value |
Bleeding Time (BT) |
3 - 10 min |
Clotting Time (CT) |
2 - 7 min |
Prothrombin Time (PT) |
10.3 - 12.8 sec |
Activated Partial Thromboplastin Time (APTT) |
25 - 37 sec |
Coagulation Profile Test Interpretation
Here are basic interpretations of Coagulation Profile Test.
Parameter |
Interpretation |
Bleeding Time (BT)
|
- Within normal range (normal clotting ability)
- Abnormal (potential bleeding tendency)
|
Clotting Time (CT) |
- Within normal range (normal clotting ability)
- Abnormal (possible clotting disorder)
|
Prothrombin Time (PT) |
- Within normal range (healthy clotting function)
- Abnormal (clotting factor deficiency or excess)
|
Activated Partial Thromboplastin Time (APTT) |
- Within normal range (healthy intrinsic pathway)
- Abnormal (potential clotting factor deficiency)
|
Coagulation Profile Test High Levels
Here are potential causes of high levels in a Coagulation Profile Test:
Parameter |
Potential Causes of High Levels |
Bleeding Time (BT) |
Typically not associated with high levels. |
Clotting Time (CT) |
Prolonged clotting time is typically not considered high levels. |
Prothrombin Time (PT) |
- Excessive intake of vitamin K
- Clotting factor deficiencies (e.g., Factor VII deficiency)
|
Activated Partial Thromboplastin Time (APTT) |
- Hemophilia A (Factor VIII deficiency)
- Hemophilia B (Factor IX deficiency)
|
Coagulation Profile Test Low Levels
Here are the potential causes of low levels in a Coagulation Profile Test:
Parameter |
Potential Causes of Low Levels |
Bleeding Time (BT) |
Typically not associated with low levels. |
Clotting Time (CT) |
Shortened clotting time is typically not considered low levels. |
Prothrombin Time (PT) |
- Liver disease (e.g., cirrhosis)
- Vitamin K deficiency
- Warfarin therapy (anticoagulant)
|
Activated Partial Thromboplastin Time (APTT) |
- Hemophilia A (Factor VIII deficiency)
- Hemophilia B (Factor IX deficiency)
- Hemophilia C (Factor XI deficiency)
- von Willebrand disease
|
Specimen Requirements For Coagulation Profile Test
Here are the specimen requirements for the Coagulation Profile Test.
Specimen Requirement |
Details |
Specimen Type |
Whole blood |
Volume |
5 ml |
Container |
Lavender-top (EDTA) tube and blue-top (sodium citrate) tubes |
Collection Instructions |
Citrated plasma samples should be collected by double centrifugation. |
Storage Conditions |
Maintain whole blood at room temperature. Freeze plasma. |
Causes for Rejection |
Severe hemolysis; improper labeling; clotted specimen; specimen diluted with IV fluids; samples thawed in transit; improper sample type; sample out of stability. |
Coagulation Profile Test is Safe?
The Coagulation Profile Test is generally considered safe and routine.
- It involves a simple blood draw, which is a common and safe procedure.
- Like most blood tests, there may be a slight risk of minor discomfort or bruising at the site of blood collection, but serious complications are rare.
When Do You Get Coagulation Profile Test Results?
- Coagulation Profile Test results are typically available within a few hours depending on the laboratory's efficiency.
- Your healthcare provider will inform you of the specific time frame for receiving your test results.
Coagulation Profile Test Limitation
Here is the basic limitation of the Coagulation Profile Test.
- Coagulation profile tests may not reflect an individual's bleeding or clotting risk in all clinical scenarios.
- Test results can be influenced by various factors, including medications and medical conditions.
- Interpretation should consider the complete clinical picture and not rely solely on these tests for diagnosis or prognosis.
Coagulation Profile Test Risk Factors
Here are some of the risk factors of the Coagulation Profile Test.
- Family history of bleeding disorders or clotting disorders.
- Use of medications that affect blood clotting, such as anticoagulants or antiplatelet drugs.
- Certain medical conditions, such as liver disease or hemophilia, can increase the risk of abnormal coagulation profiles.
Doctor Recommendations After Coagulation Profile Test Result
Here are Doctor's recommendations or consult a specialist after the Coagulation Profile Test.
Coagulation Profile Result |
Doctor to Visit |
Reason |
High |
Hematologist |
Blood clotting disorder investigation |
Normal |
Primary Care |
Routine coagulation assessment |
Low |
Hematologist |
Bleeding disorder evaluation |
Coagulation Profile Test Price
Here are the estimated Coagulation Profile Test Prices in India with different top cities:
*Prices are approximate and vary depending on a specific laboratory or healthcare facility.
Summary
Overall, Coagulation Profile test assesses blood clotting ability, aiding diagnosis of clotting disorders. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.
Reference
- Coagulation Profile Test - Wikipedia [1].
- Coagulation Tests - Clinical Methods - NIH [2].