Chromogranin A (CgA) Test for The Assessment of Neuro-Endocrine Tumors

Chromogranin A (CgA) Test for The Assessment of Neuro-Endocrine Tumors

The Chromogranin A (CgA) Test is a blood test used in medical settings to check for certain tumors, mainly in the digestive system and other organs. It helps doctors assess treatment response and prognosis in patients.

 

Chromogranin A Test

Here are the basic details of the Chromogranin A Test.

Also Known As CgA Test
Type Blood test
Purpose Detect neuroendocrine tumors
Sample Type Serum
Preparation Follow doctor's instructions
Fasting May required
Gender Unisex
Age Group All
Normal Value <100 ng/L
Reporting Time A few days
Cost 3000-6000 INR*

*Price range may vary as per location, lab type, and procedure of lab test.

 

Chromogranin A Test Means

Chromogranin A Test is a diagnostic blood test used to measure the levels of Chromogranin A in the bloodstream.

  • It assesses neuroendocrine tumors, like those in the digestive system, by detecting elevated CgA levels.
  • The test may help in monitoring treatment effectiveness and estimating prognosis for patients.
  • CgA is produced by neuroendocrine cells and its levels can vary depending on the presence and status of these tumors.
  • Interpretation of the results should consider the reference range and the patient's overall health situation.

 

Chromogranin A Test Purpose

The purpose of the Chromogranin A Test is to:

  • Chromogranin A Test diagnoses neuroendocrine tumors like digestive and lung cancers.
  • It monitors treatment response by assessing changes in CgA levels.
  • CgA test helps estimate the prognosis or recovery chances for patients.
  • Used for tumor recurrence detection after initial treatment.
  • May aid in diagnosing neuroendocrine tumors in symptomatic individuals.

Chromogranin A Test_ Price, Normal Range, Result, Purpose, Meaning and Interpretation - Drlogy Test

 

Chromogranin A Test Preparation

Here is the basic preparation for the Chromogranin A Test.

 

Before Test

  • Consult your healthcare provider for specific instructions.
  • Some tests may require fasting (not eating or drinking, except water).
  • You might be asked to stop certain medications before the test.

 

During Test

  • A blood sample is collected from a vein in your arm.
  • An elastic band is placed around your arm to facilitate blood flow.
  • The procedure is quick, with minimal discomfort.

 

After Test

  • Pressure is applied to the puncture site to stop bleeding.
  • A bandage is placed over the puncture site.
  • You can typically resume normal activities right away.

 

Chromogranin A Test Procedure

Here is the basic Chromogranin A Test Procedure.

  • Blood sample collection from a vein in the arm.
  • Elastic band placed to increase blood flow.
  • Puncture site cleaned with antiseptic.
  • Needle inserted for blood collection.
  • Once enough blood is collected, the needle is removed.
  • Pressure applied to prevent bleeding.
  • Bandage placed over the puncture site.
  • Quick procedure with minimal discomfort.

 

Chromogranin A Test Result

  • CgA test result in ng/mL (nanograms per milliliter).
  • Reference range provided by the laboratory for comparison.
  • Interpretation by your doctor in the context of your health.

 

Chromogranin A Test Normal Range

Here is the normal range of the Chromogranin A Test.

Test Name Normal Range
CgA (Chromogranin A) <100 ng/L

 

Chromogranin A Test Interpretation

Here is the Interpretation of the Chromogranin A Test.

CgA Level Interpretation
< 39 ng/L Within the normal range, no concerning issues detected.
40 - 101.9 ng/ml Mildly elevated (1 to 2-fold normal limit), further evaluation may be needed.
> 101.9 ng/ml Highly elevated (>2-fold normal limit), potentially indicating underlying health issues.

 

Chromogranin A Test High Levels

Here are some possible causes of high Chromogranin A levels.

Possible Causes Effects
Neuroendocrine tumors Most common cause, like carcinoids.
Stress Can elevate CgA temporarily.
Certain medications Some drugs may increase CgA levels.
Renal failure Kidney issues may affect CgA levels.

High Chromogranin A (CgA) levels may result from neuroendocrine tumors, stress, medications, or renal failure.

 

Chromogranin A Test Low Levels

Here are some possible causes of low Chromogranin A levels.

Possible Causes Effects
Low neuroendocrine tumor activity Reduced CgA production in the absence of active tumors.
Malabsorption or malnutrition Nutrient deficiencies may impact CgA levels.

Low Chromogranin A (CgA) levels may result from reduced neuroendocrine tumor activity or malabsorption/malnutrition.

 

Specimen Requirements For Chromogranin A Test

Here are the specimen requirements for the Chromogranin A Test.

Specimen

Serum

Volume

0.5 mL

Container

Gel-barrier tube

Collection

Transfer separated serum to a plastic transport tube.

Storage

Room temperature

Sample Stability

Temperature

Period

Room temperature

7 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Gross icterus; gross hemolysis; gross lipemia

 

Chromogranin A Test is Safe?

Chromogranin A Test is generally safe.

  • It involves a standard blood draw, a common medical procedure.
  • Minimal discomfort is expected during and after the test.
  • Any potential risks or complications are extremely rare.

 

When Do You Get Chromogranin A Test Results? 

  • Chromogranin A Test results are typically available within a few business days.
  • Your healthcare provider will discuss the results with you.
  • In some cases, results may also be accessible through an online health portal.
  • Consult your healthcare provider for specific reporting times.

 

Chromogranin A Test Limitation

Here is the basic limitation of Chromogranin A Test.

  • Elevated levels in conditions other than neuroendocrine tumors.
  • Results can vary based on the laboratory method used.
  • Test alone cannot confirm a diagnosis; further assessments required.

 

Chromogranin A Test Risk Factors

Here are some of the risk factors of the Chromogranin A Test.

  • Stress and certain medications can temporarily affect test results.
  • Chronic kidney disease may impact CgA levels.
  • High alcohol intake might contribute to CgA elevation.

 

Doctor Recommendations After Chromogranin A Test Result

 Here are the Doctor's recommendations or consult a specialist after the Chromogranin A Test.

CgA Test Result Doctor to Visit Reason
High Oncologist Evaluate for neuroendocrine tumor.
Normal Routine check-up No specific concern identified.
Low Gastroenterologist Assess malabsorption or related issues.

 

Chromogranin A Test Price

Here are the estimated Chromogranin A Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

3000-6000

New Delhi

3500-7500

Bangalore

3000-6000

Hyderabad

3500-7500

Kolkata

3000-6000

Pune

3500-7500

Lucknow

3000-6000

Noida

3500-7500

Surat

3500-7500

Gurugram

3000-6000

Patna

3500-7500

Chennai

3000-6000

Jaipur

3500-7500

Ahmedabad

3000-6000

*Prices are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall, Chromogranin A Test measures blood CgA levels, aiding in neuroendocrine tumor detection, monitoring, and prognosis assessment. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • Chromogranin A - Wikipedia [1].
  • Chromogranin A - unspecific neuroendocrine marker. ... - NIH [2].
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Chromogranin A Test FAQ

What is the Chromogranin A test?

The Chromogranin A test is a blood test that measures the level of a protein called Chromogranin A. It is used to detect and monitor neuroendocrine tumors, a rare type of cancer.

Why is Chromogranin A important?

Chromogranin A is a marker for neuroendocrine tumors, making it crucial for early detection and treatment planning. High levels may indicate tumor growth.

When is Chromogranin A testing ordered?

It is ordered when a doctor suspects or wants to monitor neuroendocrine tumors, assess treatment response, or identify recurrence.

What is the normal range for Chromogranin A?

The reference range can vary between labs, but typically, levels <100 nanograms per milliliter (ng/mL) are considered normal.

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