Carcinoembryonic Antigen (CEA) Test: Indicator of Cancer Progress

Carcinoembryonic Antigen (CEA) Test: Indicator of Cancer Progress

The CEA test, or Carcinoembryonic Antigen test, is a blood test used to monitor cancer treatment, predict how cancer might progress, and check for its return after treatment. It's valuable for patients and doctors in the cancer care journey.

 

CEA Test

Here are the basic details of the CEA Test.

Also Known As CEA Test
Type Blood test
Purpose Track, predict, and check cancer
Sample Type Serum
Preparation No
Fasting Not required
Gender Unisex
Age Group All
Normal Value <5 µg/L
Reporting Time A few days
Cost 400-800 INR*

*Price range may vary as per location, lab type, and procedure of lab test.

 

CEA Test Means

The CEA Test assesses CEA protein levels in bodily fluids, aiding in cancer prognosis, treatment progress monitoring, and recurrence detection.

  • CEA Blood Test helps doctors evaluate the effectiveness of cancer treatments, ensuring that they are on the right track to combat the disease.
  • By analyzing CEA levels and other factors, CEA Test assists in predicting how cancer may develop, allowing for more informed decisions on treatment strategies.
  • After cancer treatment, CEA Test can identify potential cancer recurrence, enabling early intervention and improved outcomes.
  • CEA Test plays a vital role in the comprehensive care of cancer patients, aiding in monitoring, prognosis, and recovery.

 

CEA Test Purpose

The purpose of the CEA Test is to:

  • CEA Test aids in estimating cancer prognosis by assessing CEA levels and other factors, helping doctors predict the course of the disease.
  • CEA Test monitors the effectiveness of cancer treatments by tracking changes in CEA levels, ensuring optimal therapy.
  • After cancer treatment, CEA Test identifies potential recurrence, enabling timely intervention and improved outcomes.
  • CEA Blood Test is used in various cancer types, including colorectal, breast, lung, thyroid, and more, to assess and manage the disease.
  • CEA Test is an integral tool in cancer care, assisting in prognosis, treatment monitoring, and post-treatment follow-up, enhancing patient care.

CEA Test_ Price, Normal Range, Result, Purpose, Procedure Meaning and Interpretation - Drlogy Test

 

CEA Test Preparation

Here is the basic preparation for the CEA Test.

 

Before Test

  • No specific preparation required.
  • Consider abstaining from smoking before the test as it can affect CEA levels.

 

During Test

  • Blood sample is taken from a vein in your arm.
  • Additional procedures needed for testing other fluids like peritoneal or cerebrospinal fluid.

 

After Test

  • Risks are generally low; side effects may include minor discomfort, tenderness, or bruising at the needle site.
  • Other fluid extractions may have different side effects, such as headaches, dizziness, or infection.
  • Discuss concerns and restrictions with your doctor.

 

CEA Test Procedure

Here is the basic CEA Test Procedure.

  • CEA Blood test involves obtaining a blood sample.
  • A needle is used to draw blood from a vein in the arm.
  • The sample is then sent to a laboratory for analysis.
  • For other fluid types, additional procedures may be required, guided by ultrasound or a lumbar puncture.
  • The entire procedure typically takes a short amount of time.
  • Patients may experience mild side effects, such as minor pain, tenderness, or bruising at the needle insertion site.

 

CEA Test Result

  • CEA Blood test reports values in ng/mL or µg/L.
  • Interpretation considers purpose and previous results.
  • High levels can suggest poor prognosis or treatment response, while decreasing levels may indicate treatment success.

 

CEA Test Normal Range

Here is the normal range of the CEA Test.

Test Normal Range
CEA Test <5 µg/L

 

CEA Test Interpretation

Here is the Interpretation of the CEA Test.

CEA Test Result Interpretation
< 3 ng/mL Normal (Non-smokers)
< 5 ng/mL Normal (Smokers)
> 10 ng/mL Extensive disease, poor prognosis
> 20 ng/mL High risk of recurrence within 14 months post-surgery
> 5 ng/mL (before therapy) Suggests localized disease and favorable prognosis

 

CEA Test High Levels

Here are potential causes of high levels of CEA Test.

Possible Causes Description
Carcinomas (endodermal origin) Colon, Stomach, Pancreas, Lung, and others
Carcinomas (non-endodermal origin) Breast, Head & Neck, Ovary, among others
Non-carcinomatous malignant disease Various malignant conditions not arising from carcinomas
Metastatic solid tumors Particularly to the liver or lungs
Malignant effusions Accumulation of cancerous fluid in body cavities
Liver disease Conditions like cirrhosis, hepatitis, obstructive jaundice
Renal failure Impaired kidney function
Fibrocystic disease of the breast Non-cancerous breast condition

High CEA levels can signal various health issues, including cancer and non-cancerous conditions, making it a valuable marker for diagnosis and prognosis.

 

CEA Test Low Levels

Here are potential causes of low levels of CEA Test.

Possible Causes Description
Normal Range CEA levels within the typical healthy range
Incomplete Resection Failure to decline to normal CEA level post-surgery
CEA-Non-Expressing Colon Cancers Some colon cancers do not express CEA
Assay Variability Different assays may produce varying CEA values
Non-Cancer-Related Conditions Normal CEA level do not rule out other health issues

Low CEA levels are often normal but should be evaluated in the context of an individual's health, as they can vary due to factors like surgery, cancer type, and assay differences.

 

Specimen Requirements For CEA Test

Here are the specimen requirements for the CEA Test.

Specimen

Serum

Volume

1 ml

Container

Gel-barrier tube (preferred) or red-top tube

Collection

If a red-top tube is used, transfer separated serum to a plastic transport tube.

Storage

Room temperature

Sample Stability

Temperature

Period

Room temperature

7 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Citrate plasma specimen; improper labeling

 

CEA Test is Safe?

  • CEA Blood Test is safe for patients.
  • It involves a simple blood sample or fluid extraction.
  • Risks are generally low, with minor side effects like bruising.
  • Some other fluids may have specific side effects.
  • It is a routine and widely used diagnostic test for cancer assessment and monitoring.

 

When Do You Get CEA Test Results? 

  • Carcinoembryonic Antigen results typically become available within a few days.
  • Results may be discussed during a follow-up appointment.
  • Some doctors may wait until additional tests are completed for a comprehensive assessment.
  • Patients may access results online or through mail in some cases.

 

CEA Test Limitation

Here is the basic limitation of CEA Test.

  • Normal CEA level doesn't rule out cancer due to non-expressing cancers.
  • Levels may not immediately return to normal post-surgery.
  • Different assays can yield varying CEA values.
  • Elevated CEA alone doesn't confirm cancer; further tests are needed.
  • CEA testing may not be effective in all cancer types.

 

CEA Test Risk Factors

Here are some of the risk factors of the CEA Test.

  • Smoking can lead to elevated CEA levels.
  • Assay variations may affect result accuracy.
  • Some non-cancerous conditions may elevate CEA.
  • Incomplete resection can influence CEA levels.
  • Patient-specific factors, such as age and overall health, can impact CEA interpretations.

 

Doctor Recommendations After CEA Test Result

 Here are the Doctor's recommendations or consult a specialist after the CEA Test.

CEA Test Result Doctor to Visit Reason
High Oncologist Further evaluation and cancer assessment
Normal Routine checkup doctor Discuss results and general health
Low Routine checkup doctor Routine assessment; no specific concern

 

CEA Test Price

Here are the estimated CEA Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

400-800

New Delhi

400-800

Bangalore

400-800

Hyderabad

400-800

Kolkata

400-800

Pune

400-800

Lucknow

400-800

Noida

400-800

Surat

400-800

Gurugram

400-800

Patna

400-800

Chennai

400-800

Jaipur

400-800

Ahmedabad

400-800

*Prices are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall, The CEA test, or Carcinoembryonic Antigen test, assesses blood levels of a protein linked to various health conditions, particularly cancer, aiding in diagnosis and monitoring. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • CEA - Wikipedia [1].
  • Carcinoembryonic Antigen - NIH [2].
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CEA Test FAQ

What is a normal tumor marker level?

Normal tumor marker levels vary depending on the specific tumor marker and the laboratory performing the test. Each tumor marker has its own reference range, which indicates the normal levels for that marker. It's important to interpret tumor marker results in the context of the individual's clinical history and other diagnostic findings. A healthcare professional can provide specific information about normal ranges for different tumor markers and guide appropriate evaluation and management based on the individual's circumstances.

What level of CEA indicates cancer?

There is no specific CEA level that definitively indicates cancer. Elevated levels may suggest cancer, but other factors must be considered for a diagnosis.

What is the Carcinoembryonic antigen test used for?

CEA test is used to monitor certain cancers, primarily colorectal. It helps track treatment effectiveness and detect recurrence.

What level of CEA indicates lung cancer?

No specific CEA level indicates lung cancer. CEA is more associated with colorectal cancer, and its role in lung cancer detection is limited.

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