CA 15-3 (Cancer Antigen 15-3) Test for Breast Cancer

CA 15-3 (Cancer Antigen 15-3) Test for Breast Cancer

The CA 15-3 (Cancer Antigen 15-3) Test measures the levels of a protein called CA 15-3 Test in the blood. CA 15-3 is a protein that is produced in normal breast cells.

 

CA 15-3 Test

Here are the basic details for CA 15-3 Test.

Also Known As Cancer Antigen 15-3
Type Blood Test
Sample Type Blood Serum
Preparation No Special Preparation Required
Fasting No
Gender Female
Age-Group 18+
Normal Value < 30 U/mL
Reporting Time 1 - 3 days
Cost 1000 - 1500 INR*

*Price range may vary as per location, lab type, and procedure of lab test.

CA 15-3 Test Full Form

Full Form of CA 15-3 Test is Cancer Antigen 15-3 Test.

 

CA 15-3 Test Means

The CA 15-3 Test measures the levels of a protein called CA 15-3 Test in the blood.

  • CA 15-3 is primarily used as a tumor marker, particularly for breast cancer.
  • Elevated levels of CA 15-3 may indicate the presence of breast cancer, but it is not diagnostic on its own and requires further evaluation by healthcare professionals.
  • The test is often used to monitor the response to treatment and detect cancer recurrence in individuals with known breast cancer.

Interesting Facts about Breast Cancer

  • Breast cancer is the most common cancer among women worldwide, accounting for a significant portion of cancer diagnoses.
  • Although rare, breast cancer can also affect men, with an estimated 1% of breast cancer cases occurring in males.
  • Early detection through regular breast self-exams, mammograms, and clinical screenings can greatly increase the chances of successful treatment and survival.

 

CA 15-3 Test Purpose

Here are the purposes of the CA 15-3 Test.

  • The CA 15-3 (Cancer Antigen 15-3) Test is primarily used as a tumor marker for breast cancer.
  • It helps in monitoring the response to treatment in individuals diagnosed with breast cancer.
  • The test is also used for surveillance and early detection of cancer recurrence in patients previously treated for breast cancer.
  • CA 15-3 levels can provide additional information about the extent or stage of breast cancer, although it is not diagnostic on its own.
  • In some cases, the CA 15-3 Test may be used to evaluate the effectiveness of targeted therapies in breast cancer treatment.

 

Cancer Antigen 15-3 Test: Price, Normal Range, Result, Purpose

 

CA 15-3 Test Preparation

Here's the CA 15-3 (Cancer Antigen 15-3) Test preparation before, during, and after the test:

 

Before Test

  • There is typically no special preparation required before the CA 15-3 Test.
  • Inform your healthcare provider about any medications or supplements you are taking, as they may affect the test results.
  • Follow any instructions given by your healthcare provider regarding fasting or specific dietary restrictions, if applicable.

 

During Test

  • The CA 15-3 Test is a blood test that involves the collection of a blood sample.
  • A healthcare professional will clean the site (usually the arm) with an antiseptic and insert a needle to draw blood.
  • The blood sample will be collected in a vial or test tube and sent to a laboratory for analysis.

 

After Test

  • Once the blood sample is collected, you can resume your normal activities.
  • There are typically no specific post-test instructions or restrictions.
  • Your healthcare provider will inform you about when and how you will receive the test results and any follow-up appointments or discussions that may be necessary.

Summary

The CA 15-3 Test requires no special preparation, involves a blood sample collection, and has no specific post-test instructions.

 

CA 15-3 Test  Procedure

Here's the CA 15-3 (Cancer Antigen 15-3) Test procedure.

  • The CA 15-3 Test is a blood test performed by a healthcare professional.
  • You will be asked to sit or lie down in a comfortable position.
  • The healthcare professional will clean the area, usually the inner elbow or back of the hand, with an antiseptic.
  • They will then apply a tourniquet above the site to make the veins more visible.
  • A needle will be inserted into a vein, and a small amount of blood will be drawn into a vial or test tube.
  • Once an adequate sample is collected, the needle will be removed, and a sterile cotton ball or bandage will be applied to the puncture site to stop any bleeding.
  • The blood sample will be labeled and sent to a laboratory for analysis.
  • You may experience a slight pinch or prick during the needle insertion, but the procedure is generally quick and relatively painless.

 

CA 15-3 Test Result

When interpreting CA 15-3 (Cancer Antigen 15-3) Test results, it's important to keep the following points in mind:

  • CA 15-3 levels can be elevated in various conditions, not just breast cancer, so further diagnostic tests are necessary to confirm a diagnosis.
  • An elevated CA 15-3 levels may indicate the presence of breast cancer or cancer recurrence, but it is not diagnostic on its own and should be evaluated in conjunction with other clinical findings.
  • Conversely, a normal CA 15-3 level does not guarantee the absence of breast cancer, as some individuals with cancer may have normal levels or other markers may be more informative in their case.

 

CA 15-3 Test Report

CA 15-3 Test Report - Drlogy Test

CA 15-3 Test Report PDF

 

CA 15-3 Test Normal Report

Ca 15 3 Breast Cancer Marker Test Normal Report Format Example Sample Template - Drlogy Pathology Lab Report Format

CA 15-3 Normal Test Report PDF Format

CA 15-3 Test Normal Result Report PDF

 

CA 15-3 Test Abnormal Report

Ca 15 3 Breast Cancer Marker Test Abnormal Report Format Example Sample Template - Drlogy Pathology Lab Report Format

CA 15-3 Abnormal Test Report PDF Format

CA 15-3 Test Abnormal Result Report PDF

 

CA 15-3 Test Normal Range

Here is the normal range for CA 15-3 Test (Cancer Antigen 15-3).

Test Result  Interpretation
< 30 U/mL Normal range
30 - 39 U/mL Borderline elevation
>= 40  U/mL Elevated levels

 

CA 15-3 Test Interpretation

Interpretation of CA 15-3 (Cancer Antigen 15-3) Test results can vary depending on the individual's medical history, the presence of cancer, and other factors.

CA 15-3 Level  Interpretation
< 30 U/mL Normal range
30 - 39 U/mL Borderline elevation
40 - 49 U/mL Mild elevation, further evaluation may be warranted
50 - 99 U/mL Moderate elevation may indicate cancer progression
>= 100 U/mL Significant elevation, the potential for cancer activity

 

CA 15-3 Test High Levels

Here are the potential causes of CA 15-3 Test High Levels.

CA 15-3 Test High Levels Causes
Breast cancer Presence or recurrence of breast cancer
Metastatic cancer Cancer spreading to other parts of the body
Benign breast conditions Non-cancerous breast conditions
Liver disease Hepatic disorders affecting CA 15-3 levels
Lung cancer Elevated CA 15-3 levels in lung cancer cases
Other cancers Elevated levels in certain other cancers

 

CA 15-3 Test Low Levels

Here are the potential causes of CA 15-3 Test Low Levels.

CA 15-3 Test Low Levels Causes
Early-stage breast cancer Absence of tumor or reduced tumor burden
Normal breast tissue Absence of abnormal cell activity
Non-cancerous conditions Benign breast conditions or infections
Recent treatment response Effective response to breast cancer therapy
Interfering medications Certain medications may lower CA 15-3 levels

Summary

High values of CA 15-3 Test (Cancer Antigen 15-3) may indicate breast cancer or other conditions, while low values are generally considered within the normal range.

 

Specimen Requirements For CA 15-3 Test

Here are the specimen requirements for the CA 15-3 Test.

Specimen Blood Serum
Volume 1 ml
Container Red Top Vacutainer tube with EDTA anticoagulant

 

CA 15-3 Test is Safe?

The CA 15-3 Test is generally considered safe and is a routine blood test performed in a clinical laboratory setting.

  • It involves a standard blood draw procedure, which carries minimal risks such as temporary discomfort, bruising, or very rarely, infection at the site of needle insertion.
  • There are no known serious or significant risks associated with the CA 15-3 Test itself, and any potential risks are generally related to the blood draw process rather than the specific test.

 

When Do You Get CA 15-3 Test Results?

The turnaround time for CA 15-3 test results can vary depending on the laboratory performing the analysis and the specific testing methods used.

  • In most cases, it takes a few days to receive the test results, typically within 1-3 days after the blood sample is collected.
  • The exact timing may also depend on various factors, including the laboratory's workload, the need for additional testing or confirmatory tests, and the method of result deliver

 

CA 15-3 Test Limitation

Here are some possible limitations of the CA 15-3 Test.

  • CA 15-3 Test (Cancer Antigen 15-3) t has limitations and should not be used as a standalone diagnostic tool for breast cancer.
  • CA 15-3 levels can be elevated in non-cancerous conditions such as liver disease, benign breast conditions, and certain infections.
  • The test is more useful for monitoring treatment response or detecting recurrence in patients already diagnosed with breast cancer.
  • False-positive and false-negative results can occur, necessitating further evaluation and additional diagnostic tests.
  • Clinical assessment and imaging studies are essential for the accurate diagnosis and management of breast cancer, in addition to the CA 15-3 test.

 

CA 15-3 Test Risk Factors

Here is the potential risk factors for elevated CA 15-3 Test (Cancer Antigen 15-3) levels include:

  • Previous diagnosis of breast cancer
  • Advanced stage of breast cancer
  • Larger tumor size
  • Estrogen receptor-positive breast cancer
  • Infections or inflammation in the breast

 

Doctor Recommendations After CA 15-3 Test Result

Here are Doctor recommendations or consult a specialist after CA 15-3 Test.

CA 15-3 Test Result Doctor to Visit Reason
High Oncologist Evaluation and management of breast cancer
Normal General Physician Routine follow-up and general medical care
Low General Physician No specific concern related to the test result

 

CA 15-3 Test Price

Here are the estimated CA 15-3 Test Price in India with top different cities:

City Price Range (INR)*
Mumbai 1000 - 1500
New Delhi 1200 - 1500
Bangalore 1000 - 1500
Hyderabad 1200 - 1500
Kolkata 1200 - 1500
Pune 1000 - 1500
Lucknow 1200 - 1500
Noida 1200 - 1500
Surat 1000 - 1500
Gurugram 1200 - 1500
Patna 1000 - 1500
Chennai 1200 - 1500
Jaipur 1000 - 1500
Ahmedabad 1200 - 1500

*Prices are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall, CA 15-3 Test is a safe and reliable blood test used as a tumor marker primarily for breast cancer, helping in monitoring treatment response and detecting cancer recurrence. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • CA 15-3 Test - Wikipedia [1].
  • Correlation of CA 15-3 Test (CA15-3) serum level and bony metastases in breast cancer patients NIH [2].

 

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CA 15-3 Test FAQ

Does a high CA 15-3 mean cancer?

A high level of CA 15-3 does not definitively mean cancer. CA 15-3 is a tumor marker primarily associated with breast cancer, but elevated levels can also occur in non-cancerous conditions. The test is used to monitor the progression of breast cancer, detect recurrence, or assess treatment response. Other factors, such as liver or lung disease, can also cause elevated CA 15-3 levels. To determine the cause of elevated CA 15-3, further evaluation, including imaging studies and additional tests, is necessary. It's important to work closely with a healthcare professional who can consider the full clinical picture and recommend appropriate follow-up investigations for an accurate diagnosis.

What is a normal CA 15-3 level?

The normal range for CA 15-3 can vary depending on the laboratory, but typically, levels below 30 U/mL are considered within the normal range. However, it's crucial to understand that a normal CA 15-3 level does not exclude the presence of cancer. CA 15-3 is primarily used as a tumor marker for breast cancer, but elevated levels can also occur in benign conditions or other types of cancer. Therefore, the interpretation of CA 15-3 results should be done in conjunction with other clinical findings and diagnostic tests. Consulting with a healthcare professional is important to understand the individual's specific situation and determine the significance of CA 15-3 levels.

What is CA 15-3 test for?

The CA 15-3 test is a blood test used to measure the levels of a protein called cancer antigen 15-3 (CA 15-3) in the blood. It is primarily used as a tumor marker for breast cancer. The test is not diagnostic on its own but can be helpful in monitoring the progression of breast cancer or detecting a recurrence. Elevated CA 15-3 levels may indicate the presence of breast cancer, but it can also be elevated in other conditions such as liver disease, lung disease, or other types of cancer. Follow-up tests and imaging studies are typically required to confirm a diagnosis.

Is CA 15-3 a tumor marker?

Yes, CA 15-3 is considered a tumor marker, specifically for breast cancer. Tumor markers are substances produced by cancer cells or by normal cells in response to cancer. They can be detected in blood, urine, or tissue samples and are used to aid in cancer diagnosis, monitoring treatment response, and detecting cancer recurrence. However, it's important to note that elevated CA 15-3 levels are not exclusive to breast cancer and can be seen in other conditions, so the test should not be used as the sole basis for a diagnosis.

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