Pax8 Test is a medical test used to check for certain proteins related to thyroid and kidney cancers, assisting doctors in diagnosing and managing these health conditions.
Here are the basic details of the Pax8 Test.
Also Known As | Pax8 Immunohistochemistry (IHC) or Pax8 Staining |
Type | Immunohistochemistry |
Purpose | To detect Pax8 protein expression in tissue samples |
Sample Type | Tissue |
Preparation | No |
Fasting | Not applicable |
Gender | Unisex |
Age Group | All |
Normal Value | Negative |
Reporting Time | 1 day |
Cost | 3000-5000 INR* |
*Price range may vary as per location, lab type, and procedure of lab test.
The Pax8 Test is a medical procedure used to identify Pax8 protein levels, aiding in the diagnosis and management of various cancers, notably Kidney, ovarian, and thyroid cancers.
The purpose of the Pax8 Test is to:
Here is the basic preparation for the Pax8 Test.
Here is the basic Pax8 Test Procedure.
Pax 8 Test Normal Result:
Pax 8 Test Abnormal Result:
Here is the normal result of the Pax8 Test.
Test | Normal Results |
---|---|
Pax8 Test | Negative |
Here is the Interpretation of the Pax8 Test.
Test Results | Interpretation |
---|---|
Positive | Suggestive of metastatic ovarian serous carcinoma. |
Negative | Less likely to indicate metastatic ovarian serous carcinoma. |
A positive result is suggestive of metastatic ovarian serous carcinoma in cytological preparations, with a negative result being less indicative of this condition.
Here are the potential causes of a positive Pax8 Test:
Possible Causes | Description |
---|---|
Ovarian Serous Carcinoma | Indicates presence in cytological preparations |
Thyroid Tumors | Associated with Pax8 expression |
Renal Tumors | Pax8 is expressed in renal cell carcinoma |
Primary Peritoneal Serous Carcinoma | Pax8 positivity may be observed |
Müllerian-Type Ovarian Carcinomas | Pax8 often present in these tumors |
Positive Pax8 Test results may indicate the presence of ovarian serous carcinoma, thyroid tumors, renal tumors, primary peritoneal serous carcinoma, or Müllerian-type ovarian carcinomas.
Here are the potential causes of a negative Pax8 Test:
Possible Causes | Description |
---|---|
Healthy | A negative result in healthy individuals. |
Non-PAX8 Positive Tumors | Negative results in cases without PAX8-positive tumors. |
Non-thyroid or Kidney Disorders | Negative results in the absence of thyroid or kidney-related issues. |
Other Health Conditions | Absence of Pax8-related disorders or malignancies in test results. |
PAX8 Test Negative Results: Indicative of health or absence of PAX8-related tumors and thyroid/kidney disorders.
Here are the specimen requirements for the Pax8 Test.
Specimen |
Serum |
|
Volume |
1 ml |
|
Container |
Red-top tube or gel-barrier tube |
|
Collection |
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping. |
|
Storage |
Refrigerate or freeze. |
|
Sample Stability |
Temperature |
Period |
Room temperature |
7 day |
|
Refrigerated |
14 days |
|
Frozen |
60 days |
|
Freeze/thaw cycles |
Stable x1 |
|
Causes for Rejection |
Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types |
Here is the basic limitation of the Pax8 Test.
Here are some of the risk factors of the Pax8 Test.
Here are the Doctor's recommendations or consult a specialist after the Pax8 Test.
Test Result | Doctor to Visit | Reason to Go |
---|---|---|
Positive | Endocrinologist | Further evaluation and treatment. |
Negative | No specific doctor | Discuss general health concerns. |
Here are the estimated Pax8 Test Prices in India with different top cities:
City |
Price Range (INR)* |
3000-5000 |
|
3500-5000 |
|
3000-5000 |
|
3500-5000 |
|
3000-5000 |
|
3500-5000 |
|
3000-5000 |
|
3500-5000 |
|
3500-5000 |
|
3000-5000 |
|
3500-5000 |
|
3000-5000 |
|
3500-5000 |
|
3000-5000 |
*Prices are approximate and vary depending on a specific laboratory or healthcare facility.
Summary
Overall, The Pax8 Test helps distinguish thyroid carcinoma, while detecting ovarian serous carcinoma metastasis. It aids in cancer diagnosis and treatment decisions. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.
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