Pax8 Test For Kidney Cell and Thyroid

Pax8 Test For Kidney Cell and Thyroid

Pax8 Test is a medical test used to check for certain proteins related to thyroid and kidney cancers, assisting doctors in diagnosing and managing these health conditions.

 

Pax8 Test

Here are the basic details of the Pax8 Test.

Also Known As Pax8 Immunohistochemistry (IHC) or Pax8 Staining
Type Immunohistochemistry
Purpose To detect Pax8 protein expression in tissue samples
Sample Type Tissue
Preparation No
Fasting Not applicable
Gender Unisex
Age Group All
Normal Value Negative
Reporting Time 1 day
Cost 3000-5000 INR*

*Price range may vary as per location, lab type, and procedure of lab test.

 

Pax8 Test Means

The Pax8 Test is a medical procedure used to identify Pax8 protein levels, aiding in the diagnosis and management of various cancers, notably Kidney, ovarian, and thyroid cancers.

  • This test plays a crucial role in the early detection of ovarian cancer by assessing Pax8 protein, enabling timely intervention and treatment.
  • Pax8 Test assists in evaluating thyroid nodules and thyroid cancer, guiding healthcare professionals in determining appropriate treatment strategies.
  • Pax8 Test requires a blood sample, making it a non-invasive and convenient screening tool for cancer, reducing patient discomfort.
  • By analyzing Pax8 protein expression, healthcare providers can tailor treatment plans to individual patients, optimizing cancer care and outcomes.

 

Pax8 Test Purpose

The purpose of the Pax8 Test is to:

  • The Pax8 Test is instrumental in detecting ovarian and thyroid cancers in their early stages, improving treatment outcomes and survival rates.
  • It helps healthcare professionals monitor cancer progression and treatment effectiveness through Pax8 protein analysis.
  • By assessing Pax8 protein levels, treatment plans can be customized to suit individual patient needs, enhancing therapeutic efficacy.
  • The test aids in assessing a person's risk for ovarian and thyroid cancers, enabling proactive health management and prevention strategies.
  • The Pax8 Test requires only a blood sample, making it a convenient and non-invasive method for cancer screening and monitoring.

Pax8 Test- Price, Normal Range, Result, Purpose, Procedure Meaning and Interpretation - Drlogy Test

 

Pax8 Test Preparation

Here is the basic preparation for the Pax8 Test.

 

Before Test

  • No dietary or fasting requirements.
  • Inform your healthcare provider of medications or allergies.
  • Stay relaxed and stress-free before the test.

 

During Test

  • Blood will be drawn from your vein.
  • Keep still during the procedure.
  • Minor discomfort may be experienced during the blood draw.

 

After Test

  • You can return to your usual activities.
  • Results will be communicated by your healthcare provider.
  • Discuss results and any required next steps with your provider.

 

Pax8 Test Procedure

Here is the basic Pax8 Test Procedure.

  • A blood sample is collected from a vein.
  • The blood is sent to a laboratory for analysis.
  • Results are reported by a healthcare provider.

 

Pax8 Test Result

  • Positive results may indicate Pax8-related conditions.
  • A negative result suggests the absence of Pax8-related issues.
  • Healthcare provider interpretation is necessary for accurate assessment.

 

Pax 8 Test Negative Result Report

Pax 8 Test Negative Result Report Format Normal Value

Pax 8 Test Normal Result:

Pax 8 Test Negative Result Report PDF

 

Pax 8 Test Positive Result Report

Pax 8 Test Positive Result Report Format

Pax 8 Test Abnormal Result:

Pax 8 Test Positive Result Report PDF

 

Pax8 Test Normal Results

Here is the normal result of the Pax8 Test.

Test Normal Results
Pax8 Test Negative

 

Pax8 Test Interpretation

Here is the Interpretation of the Pax8 Test.

Test Results Interpretation
Positive Suggestive of metastatic ovarian serous carcinoma.
Negative Less likely to indicate metastatic ovarian serous carcinoma.

A positive result is suggestive of metastatic ovarian serous carcinoma in cytological preparations, with a negative result being less indicative of this condition.

 

Pax8 Test Positive Results

Here are the potential causes of a positive Pax8 Test:

Possible Causes Description
Ovarian Serous Carcinoma Indicates presence in cytological preparations
Thyroid Tumors Associated with Pax8 expression
Renal Tumors Pax8 is expressed in renal cell carcinoma
Primary Peritoneal Serous Carcinoma Pax8 positivity may be observed
Müllerian-Type Ovarian Carcinomas Pax8 often present in these tumors

Positive Pax8 Test results may indicate the presence of ovarian serous carcinoma, thyroid tumors, renal tumors, primary peritoneal serous carcinoma, or Müllerian-type ovarian carcinomas.

 

Pax8 Test Negative Results

Here are the potential causes of a negative Pax8 Test:

Possible Causes Description
Healthy A negative result in healthy individuals.
Non-PAX8 Positive Tumors Negative results in cases without PAX8-positive tumors.
Non-thyroid or Kidney Disorders Negative results in the absence of thyroid or kidney-related issues.
Other Health Conditions Absence of Pax8-related disorders or malignancies in test results.

PAX8 Test Negative Results: Indicative of health or absence of PAX8-related tumors and thyroid/kidney disorders.

 

Specimen Requirements For Pax8 Test

Here are the specimen requirements for the Pax8 Test.

Specimen

Serum

Volume

1 ml

Container

Red-top tube or gel-barrier tube

Collection

Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.

Storage

Refrigerate or freeze.

Sample Stability

Temperature

Period

Room temperature

7 day

Refrigerated

14 days

Frozen

60 days

Freeze/thaw cycles

Stable x1

Causes for Rejection

Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types

 

Pax8 Test is Safe?

  • Generally a safe diagnostic procedure.
  • Low risks associated with this test.
  • Always consult your healthcare provider for safety-related questions.

 

When Do You Get Pax8 Test Results? 

  • Results are typically available in a day.
  • May vary depending on the testing facility.
  • Contact your healthcare provider for specific timing.

 

Pax8 Test Limitation

Here is the basic limitation of the Pax8 Test.

  1. Interpretation may require expertise in pathology.
  2. Results should be correlated with clinical data.
  3. False negatives or positives can occasionally occur.
  4. Test performance can vary among different labs.
  5. It's part of a diagnostic process, not standalone.

 

Pax8 Test Risk Factors

Here are some of the risk factors of the Pax8 Test.

  • Risk may be associated with specific health conditions.
  • Age and gender may influence the need for this test.
  • Clinical history and symptoms guide test decisions.
  • Test utilization varies based on the healthcare provider.
  • Individual health factors play a role in test necessity.

 

Doctor Recommendations After Pax8 Test Result

 Here are the Doctor's recommendations or consult a specialist after the Pax8 Test.

Test Result Doctor to Visit Reason to Go
Positive Endocrinologist Further evaluation and treatment.
Negative No specific doctor Discuss general health concerns.

 

Pax8 Test Price

Here are the estimated Pax8 Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

3000-5000

New Delhi

3500-5000

Bangalore

3000-5000

Hyderabad

3500-5000

Kolkata

3000-5000

Pune

3500-5000

Lucknow

3000-5000

Noida

3500-5000

Surat

3500-5000

Gurugram

3000-5000

Patna

3500-5000

Chennai

3000-5000

Jaipur

3500-5000

Ahmedabad

3000-5000

*Prices are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall, The Pax8 Test helps distinguish thyroid carcinoma, while detecting ovarian serous carcinoma metastasis. It aids in cancer diagnosis and treatment decisions. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • Pax8 - Wikipedia [1].
  • PAX8 is a novel marker for differentiating between various ... - NIH [2].

 

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Pax8 Test FAQ

What is a PAX8 test?

The PAX8 test is a diagnostic test used to detect the presence of PAX8 protein in tissue samples. It helps identify various cancer types and plays a crucial role in cancer diagnosis.

What does PAX8 positive mean?

A PAX8-positive result in a test indicates the presence of PAX8 protein in the tested tissue. This may suggest the involvement of PAX8 in the development or progression of certain cancers, such as thyroid or ovarian cancer.

Is PAX8 positive for thyroid cancer?

Yes, PAX8 is commonly found in thyroid cancer. A positive PAX8 result in a thyroid tissue sample can indicate the presence of thyroid cancer or be used to confirm the diagnosis. It is a valuable biomarker for thyroid cancer.

Is PAX8 positive for lung cancer?

PAX8 is typically not associated with lung cancer. It is more commonly linked to thyroid, ovarian, and renal (kidney) cancers. PAX8 testing is not a typical diagnostic tool for lung cancer.

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