PAPP-A (Pregnancy associated plasma protein-A) For Down Syndrome

Pregnancy associated plasma protein-A Test checks a protein in pregnant women's blood to assess pregnancy health and possible risks like preterm birth or preeclampsia.

PAPP-A Test

Here are the basic details of the PAPP-A Test.

*Price range may vary as per location, lab type, and procedure of lab test.

PAPP-A Test Means

PAPP-A Test measures Pregnancy-Associated Plasma Protein-A levels in a pregnant woman's blood.

• It screens for potential pregnancy complications like preterm birth or preeclampsia.
• Helps assess risk factors and ensures proper monitoring during pregnancy.
• Provides valuable information to healthcare providers for decision-making.
• It contributes to a healthier pregnancy journey.

PAPP-A Test Purpose

The purpose of the PAPP-A Test is to:

• Assesses the health of a pregnancy, helping detect complications like preterm birth and preeclampsia.
• Evaluates the risk of issues such as low birth weight and mid-trimester miscarriage.
• Provides data for personalized pregnancy management based on test results.
• Allows healthcare providers to take necessary measures for a healthy pregnancy.
• Aids in monitoring the baby's growth and overall health during pregnancy.

PAPP-A Test Preparation

Here is the basic preparation for the PAPP-A Test.

Before Test

• Typically, no special preparation is required.
• Wear clothing that allows easy access to your arm for blood collection.
• Follow any specific instructions from your healthcare provider.

During Test

• A blood sample will be collected from a vein in your arm using a needle.
• The process may cause a slight, momentary discomfort.

After Test

• You can resume your normal activities and diet.
• Discuss the test results with your healthcare provider for further guidance.

PAPP-A Test Procedure

Here is the basic PAPP-A Test Procedure.

• Blood sample collected from a vein in your arm using a needle.
• The sample is then sent to a laboratory for analysis.
• Results are typically available in a timely manner.

PAPP-A Test Result

• PAPP-A level in blood assesses pregnancy risks.
• Interpretation by healthcare providers guides monitoring and care.

PAPP-A Test Abnormal Result Report For High Levels

PAPP-A Test Abnormal Report For High Levels

PAPP-A Test Abnormal Result Report

PAPP-A Test Normal Result Report For Low Levels

PAPP-A Test Normal Report For Low Levels

PAPP-A Test Normal Result Report

PAPP-A Test Normal Range

Here is the normal range of the PAPP-A Test.

PAPP-A Test Interpretation

Here is the Interpretation of the PAPP-A Test.

PAPP-A levels vary with gestational age, aiding in pregnancy assessment, while decreased levels are used for genetic screening.

PAPP-A Test High Levels

Here are the potential causes of high PAPP-A Test levels:

Elevated PAPP-A levels are typically associated with pregnancy and can also indicate acute coronary syndrome, while the test is commonly used for maternal care screening.

PAPP-A Test Low Levels

Here are the potential causes of low PAPP-A Test levels:

Low PAPP-A levels may indicate genetic conditions like Down syndrome and Edwards syndrome, serving as markers in maternal screening.

Specimen Requirements For PAPP-A Test

Here are the specimen requirements for the PAPP-A Test.

PAPP-A Test is Safe?

PAPP-A Tis considered safe for pregnant individuals.

• Involves a routine blood draw with minimal risks.
• Results aid in monitoring and ensuring a safe pregnancy.
• Administered as part of standard prenatal care.

When Do You Get PAPP-A Test Results? 

• Results are typically available within one to 4 days.
• Healthcare provider shares results during prenatal care.

PAPP-A Test Limitation

Here is the basic limitation of the PAPP-A Test.

• Results should be interpreted in conjunction with other prenatal tests.
• Not a diagnostic test; used for screening and risk assessment.
• False positives or negatives may occur; confirmatory tests may be needed.
• Limited to assessing specific pregnancy-related risks.
• Cannot identify all possible genetic conditions.

PAPP-A Test Risk Factors

Here are some of the risk factors of the PAPP-A Test.

• Advanced maternal age may impact results, influencing pregnancy assessment.
• Twins or more can lead to variations in PAPP-A levels, affecting risk assessment.
• Higher BMI may influence the interpretation of PAPP-A results, impacting pregnancy monitoring.
• Smoking during pregnancy can alter PAPP-A levels, affecting risk assessment and maternal care.
• Certain underlying health issues can impact PAPP-A results, influencing pregnancy evaluation.

Doctor Recommendations After PAPP-A Test Result

 Here are the Doctor's recommendations or consult a specialist after the PAPP-A Test.

PAPP-A Test Price

Here are the estimated PAPP-A Test Prices in India with different top cities:

*Prices are approximate and vary depending on a specific laboratory or healthcare facility.

Summary

Overall, The PAPP-A test assesses pregnancy-related risks and is a component of standard prenatal screening during the first trimester. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

Reference

• Pappalysin-1 - Wikipedia [1].
• First Trimester Maternal Serum Screening Using ... - NIH [2].