The Cold Agglutinins Test is a blood test that helps identify autoimmune antibodies that affect red blood cells when exposed to cold. It's used to diagnose a rare condition called Cold Agglutinin Disease, which can lead to anemia and symptoms like fatigue and pain in cold temperatures.
Here are the basic details of the Cold Agglutinins Test.
Also Known As | Cold Agglutinin Blood Test |
Type | Blood Test |
Purpose | Diagnose Cold Agglutinin Disease and hemolytic anemia. |
Sample Type | Serum |
Preparation | No |
Fasting | Not required |
Gender | Unisex |
Age Group | All |
Normal Value | 1:64 or 1:512 |
Reporting Time | A few days |
Cost | 300-800 INR* |
*Cold Agglutinins Test Price range may vary as per location, lab type, and procedure of lab test.
Cold Agglutinins Test is a diagnostic blood test that detects autoimmune antibodies affecting red blood cells when exposed to cold temperatures.
The purpose of the Cold Agglutinins Test is to:
Here is the basic preparation for the Cold Agglutinins Test.
Here is the basic Cold Agglutinins Test Procedure.
Here is basic meaning of Cold Agglutinins Test.
Here is the normal result of the Cold Agglutinins Test.
Test | Normal Result |
---|---|
Cold Agglutinins Titer | 1:64 or 1:512 |
Here is the Interpretation of the Cold Agglutinins Test.
Test Result | Interpretation |
---|---|
1:64 or lower | Normal result, within the expected range. |
1:128 to 1:512 | Elevated titer, may indicate the presence of cold agglutinins. |
1:1024 or higher | High titer, often associated with more severe hemolytic anemia and symptoms. |
A Cold Agglutinins Test measures cold agglutinin levels, with higher titers potentially indicating Cold Agglutinin Disease or related conditions.
Here are the potential causes of positive Cold Agglutinins Test.
Possible Causes | Effects |
---|---|
Cold Agglutinin Disease | Hemolytic anemia, fatigue, cold-related symptoms. |
Infections (e.g., Mycoplasma pneumoniae) | Increased cold agglutinins, potential anemia. |
Certain Cancers (e.g., lymphoma, leukemia) | Elevated cold agglutinins, anemia in some cases. |
Other Infections (e.g., HIV, influenza) | Raised cold agglutinins, potential for anemia. |
Parasitic Infections (e.g., malaria) | Increased cold agglutinins, risk of anemia. |
Bacterial Infections (e.g., syphilis) | Elevated cold agglutinins, potential anemia. |
A positive Cold Agglutinins Test can indicate various causes, including Cold Agglutinin Disease, infections, and certain cancers.
Here are the potential causes of negative Cold Agglutinins Test.
Causes | Effects |
---|---|
Absence of Cold Agglutinin Disease | No associated hemolytic anemia or cold symptoms. |
Lack of relevant infections or diseases | No elevated cold agglutinins or related effects. |
Normal antibody response | Within the expected range of titer values. |
A negative Cold Agglutinins Test suggests the absence of Cold Agglutinin Disease and related conditions, indicating a normal result.
Here are the specimen requirements for the Cold Agglutinins Test.
Specimen |
Serum |
|
Volume |
1 ml |
|
Container |
Red-top tube or gel-barrier tube |
|
Collection |
Transport blood to lab, incubate at 37°C for clotting; if no incubator, allow room temp clotting, then separate serum. |
|
Storage |
Refrigerate |
|
Causes for Rejection |
Refrigeration of the specimen before separating serum from cells |
Here is the basic limitation of Cold Agglutinins Test.
Here are some of the risk factors of the Cold Agglutinins Test.
Here are the Doctor's recommendations or consult a specialist after the Cold Agglutinins Test.
Test Result | Doctor to Visit | Reason |
---|---|---|
Positive | Hematologist | Diagnose and manage related conditions. |
Negative | Consulting physician | Discuss overall health and symptoms. |
Here are the estimated Cold Agglutinins Test Prices in India with different top cities:
City |
Price Range (INR)* |
300-800 |
|
350-750 |
|
300-800 |
|
350-750 |
|
300-800 |
|
350-750 |
|
300-800 |
|
350-750 |
|
350-750 |
|
300-800 |
|
350-750 |
|
300-800 |
|
350-750 |
|
300-800 |
*Prices are approximate and vary depending on a specific laboratory or healthcare facility.
Summary
Overall, The Cold Agglutinins Test detects antibodies impacting red blood cells in cold temperatures. It helps diagnose Cold Agglutinin Disease and related conditions. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.
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