Anti Soluble Liver Antigen (SLA) Test For Type 1 Autoimmune Hepatitis

Anti Soluble Liver Antigen (SLA) Test For Type 1 Autoimmune Hepatitis

Anti Soluble Liver Antigen (SLA) Test helps doctors diagnose liver conditions by detecting specific antibodies, like a fingerprint for liver problems.

 

SLA Test

Here are the basic details of the SLA Test.

Also Known As Soluble Liver Antigen (SLA) Test
Type Blood test (Serum)
Purpose Diagnosis of autoimmune hepatitis, especially type 1 AIH.
Sample Type Serum
Preparation No
Fasting Not required
Gender Unisex
Age Group All
Normal Value Negative
Reporting Time A few hours
Cost
1000-1600 INR*

*SLA Test Price range may vary as per location, lab type, and lab test procedure.

 

SLA Test Means

SLA Test refers to the Soluble Liver Antigen Test, a blood test used to diagnose autoimmune hepatitis and liver conditions.

  • It detects specific antibodies associated with autoimmune liver disorders.
  • The test aids in distinguishing between different types of autoimmune hepatitis, particularly AIH type 1.
  • SLA Test results are reported as negative, equivocal, or positive based on reference values.
  • It plays a crucial role in the diagnosis and management of liver diseases.

 

SLA Test Purpose

The purpose of the SLA Test is to:

  • SLA Test helps doctors diagnose autoimmune hepatitis, particularly type 1 AIH, by detecting specific antibodies in the blood.
  • It aids in distinguishing autoimmune liver disorders from other liver conditions.
  • The test assists in determining the most appropriate treatment for patients with autoimmune hepatitis.
  • SLA Test is vital for understanding the underlying cause of liver-related symptoms and guiding medical interventions.
  • It plays a crucial role in the early diagnosis and management of autoimmune liver diseases.

SLA Test- Price, Normal Range, Result, Purpose, Procedure Meaning and Interpretation - Drlogy Test

 

SLA Test Preparation

Here is the basic preparation for the SLA Test.

 

Before Test

  • No specific dietary or fasting requirements.
  • Follow any pre-test instructions provided by your healthcare provider.
  • Inform your healthcare provider about any medications you are taking.

 

During Test

  • A blood sample will be collected from a vein in your arm.
  • You may experience a brief needle prick or mild discomfort during the blood draw.
  • Relax and follow the instructions of the healthcare professional.

 

After Test

  • Resume your regular activities.
  • Your healthcare provider will inform you of the test results.
  • Discuss any necessary follow-up steps.

 

SLA Test Procedure

Here is the basic SLA Test Procedure.

  • Blood samples were collected from a vein in the arm.
  • A healthcare professional cleans the area and inserts a needle.
  • Blood is drawn into a vial.
  • The sample is sent to a laboratory for analysis.
  • Test results are reported by a healthcare provider.

 

SLA Test Result

Here is the basic reading of the SLA Test results.

  • Negative results: Usually within the reference range.
  • Equivocal results: Falling slightly outside the reference range.
  • Positive results: Significantly exceeding the reference range.

 

SLA Test Positive Result Report

ANTI SOLUBLE LIVER ANTIGEN SLA Test Negative Result Report Format - Drlogy test

SLA Test Positive Report

SLA Test Positive Result Report PDF

 

SLA Test Negative Result Report

ANTI SOLUBLE LIVER ANTIGEN SLA Test Negative Result Report Format - Drlogy Test

SLA Test Negative Report

SLA Test Negative Result Report PDF

 

SLA Test Normal Range

Here is the normal range of the SLA Test.

Test Name Normal Range
ANTI SOLUBLE LIVER ANTIGEN (SLA), SERUM (EIA) <12.00 U/mL

 

SLA Test Interpretation

Here is the Interpretation of the SLA Test.

SLA Test Result Interpretation
<12.00 Typically considered normal.
12.00 or higher May indicate autoimmune hepatitis or liver condition.

SLA test results below 12.00 U/mL are typically normal, while values at or above 12.00 U/mL may suggest autoimmune hepatitis or liver conditions.

 

SLA Test Positive Results

Here are the potential causes of positive SLA Test results:

Causes Description
Autoimmune Hepatitis (AIH) A positive SLA test often indicates AIH, particularly type 1 AIH.
Liver-Related Disorders Elevated SLA levels may be linked to various liver conditions.
Primary Biliary Cirrhosis-AIH Overlap Syndrome In some cases, SLA antibodies are found in this overlap syndrome.
Cryptogenic Hepatitis Positive SLA results in patients with cryptogenic hepatitis suggest AIH type 1.
AIH Type 1 SLA antibodies are most closely associated with AIH type 1.

Positive SLA test results may indicate autoimmune hepatitis (AIH), liver-related disorders, or AIH type 1, offering critical diagnostic insights.

 

SLA Test Negative Results

Here are the potential causes of negative SLA Test results:

Cause Description
Non-AIH Liver Conditions Negative SLA results may suggest other liver conditions.
Healthy Individuals Individuals with no autoimmune hepatitis or liver disorders.
AIH Type 2 SLA antibodies are not typically associated with AIH type 2.
Non-Specific Symptoms Negative results may indicate non-specific symptoms.
Hepatitis Types SLA test may not detect markers for other hepatitis types.

Negative SLA test results suggest the absence of autoimmune hepatitis (AIH) and may indicate non-AIH-related liver conditions or health in individuals without specific symptoms.

 

Specimen Requirements For SLA Test

Here are the specimen requirements for the SLA Test.

Specimen

Serum

Volume

0.6 mL

Container

Red-top tube or gel-barrier tube

Collection

If a red-top tube is used, transfer the separated serum to a plastic transport tube.

Storage

Room temperature

Sample Stability

Temperature

Period

Room temperature

7 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Nonserum specimen received; specimen in azide or other preservative; heat-treated specimen; gross lipemia or hemolysis

 

SLA Test is Safe?

  • Generally safe and well-tolerated.
  • Standard blood test procedure.
  • Minimal risk of complications.
  • Performed by trained healthcare professionals.
  • Benefits outweigh potential risks.

 

When Do You Get SLA Test Results? 

  • Usually within a few hours after the test.
  • Reporting time may vary depending on the laboratory.
  • Results delivered by your healthcare provider or lab.

 

SLA Test Limitation

Here is the basic limitation of the SLA Test.

  • May not identify all cases of autoimmune hepatitis.
  • Results are only one part of the diagnostic process.
  • False positives or negatives may occur in rare cases.
  • The test may not detect specific liver conditions.
  • Clinical judgment and additional tests are often necessary.

 

SLA Test Risk Factors

Here are some of the risk factors of the SLA Test.

  • Routine blood test with minimal specific risk factors.
  • Standard precautions are followed during blood collection.
  • Risks are mainly associated with the blood draw process itself.
  • Performed by trained healthcare professionals.
  • No unique risk factors are directly linked to the SLA test.

 

Doctor Recommendations After SLA Test Result

 Here are the Doctor's recommendations or consult a specialist after the SLA Test.

Test Result Doctor to Visit Reason to Visit
Positive Hepatologist Address autoimmune hepatitis.
Negative No specific doctor Depending on symptoms, consult the relevant specialist.

 

SLA Test Price

Here are the estimated SLA Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

1000-1550

New Delhi

1000-1600

Bangalore

1000-1550

Hyderabad

1000-1600

Kolkata

1000-1550

Pune

1000-1600

Lucknow

1000-1550

Noida

1000-1600

Surat

1000-1600

Gurugram

1000-1550

Patna

1000-1600

Chennai

1000-1550

Jaipur

1000-1600

Ahmedabad

1000-1550

*SLA Test Price are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall, The SLA Test, also known as Soluble Liver Antigen Test, helps diagnose autoimmune hepatitis, particularly AIH type 1, and other liver conditions through the detection of specific antibodies in the blood. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • Autoimmune hepatitis - Wikipedia [1].
  • Anti-soluble liver antigen (SLA) antibodies in chronic HCV ... - NIH [2].

 

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SLA Test FAQ

What is anti-soluble liver antigen test?

The anti-soluble liver antigen (SLA) test is a blood test used to detect antibodies against specific liver antigens associated with autoimmune hepatitis.

What is SLA positive?

SLA positive means that the test detected the presence of antibodies against soluble liver antigens, which can be indicative of autoimmune hepatitis or liver-related autoimmune disorders.

What is the full form of SLA blood test?

SLA stands for Soluble Liver Antigen, and the blood test is used to detect antibodies against these antigens, which are associated with autoimmune hepatitis.

What is anti SLA in autoimmune hepatitis?

In autoimmune hepatitis, anti-SLA antibodies are immune proteins that target soluble liver antigens. Their presence can be an indicator of autoimmune hepatitis, a chronic liver disease.

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