Ammonia Test To Diagnose and Monitor Hepatic Encephalopathy

Ammonia Test To Diagnose and Monitor Hepatic Encephalopathy

An Ammonia Test checks the amount of ammonia in your blood, which can reveal potential health problems, especially related to the liver and genetic conditions. It helps doctors diagnose and monitor these issues.

 

Ammonia Test

Here are the basic details of the Ammonia Test.

Also Known As Blood Ammonia Test
Type Blood Test
Purpose Diagnose and monitor liver and genetic conditions
Sample Type Plasma
Preparation Fasting for several hours
Fasting Often required
Gender Unisex
Age Group All
Normal Value 15 to 45 µ/dL
Reporting Time Within 24 hours
Cost 480-800 INR*

*Price range may vary as per location, lab type, and procedure of lab test.

 

Ammonia Test Means

  • Ammonia Test measures ammonia levels in the blood to detect hyperammonemia, a condition linked to liver damage and genetic disorders.
  • It helps diagnose liver disease and assess the effectiveness of treatment in hyperammonemia cases.
  • The test involves a venous or arterial blood draw, with results indicating potential health problems.
  • Proper test preparation, including fasting and medication adjustments, may be necessary for accurate results.
  • The cost of an Ammonia Test can vary, depending on the location and lab, making it essential to check with the specific facility for pricing.

 

Ammonia Test Purpose

The purpose of the Ammonia Test is to:

  • Ammonia Test evaluates blood ammonia levels, aiding in liver disease diagnosis.
  • Detects hyperammonemia, crucial for patients' monitoring and treatment.
  • Identifies genetic conditions affecting the urea cycle, ensuring prompt intervention.
  • Assesses liver function in individuals with elevated ammonia levels.
  • Helps prevent complications and long-term brain damage due to hyperammonemia.

Ammonia Test_ Price, Normal Range, Result, Purpose, Meaning and Interpretation - Drlogy Test

 

Ammonia Test Preparation

Here is the basic preparation for the Ammonia Test.

 

Before Test

  • Fast for several hours, as instructed by your healthcare provider.
  • Follow any medication adjustments recommended by your doctor.
  • Inform your healthcare provider about any relevant medical history or medications.

 

During Test

  • Blood sample is drawn through a vein or artery.
  • Expect mild discomfort, usually a quick sting or pressure.

 

After Test

  • Pressure is applied to the site to stop bleeding.
  • A bandage is placed over the puncture area.
  • Minor soreness and bruising are common and usually temporary.

 

Ammonia Test Procedure

Here is the basic Ammonia Test Procedure.

  • Blood sample drawn, typically from a vein (venous blood draw).
  • May also be collected from an artery (arterial blood draw).
  • Sample handled by a healthcare professional.
  • Results usually available within days.
  • Cost varies by location and lab; inquire with the specific facility.

 

Ammonia Test Result

  • Ammonia level measured in μg/dL or μmol/L.
  • Reference range indicates expected healthy values.
  • Elevated levels suggest possible health issues; further tests often needed.

 

Ammonia Test Normal Range

Here is the normal range of the Ammonia Test.

Age Group Normal Range
Infants 40-80 μg/dL (14-42 μmol/L)
Children 20-60 μg/dL (7-21 μmol/L)
Adults 11-35 μg/dL (4-12 μmol/L)

 

Ammonia Test Interpretation

Here is the Interpretation of the Ammonia Test.

Result Interpretation
High Potential liver or genetic issues; further evaluation needed.
Normal Typically no concerns; varies by age group.
Low Uncommon; consult with a healthcare provider for evaluation.

Ammonia test measures blood ammonia levels to identify potential liver or genetic issues and is interpreted based on whether the result is high, normal, or low.

 

Ammonia Test High Levels

Here are some possible causes of high ammonia levels:

Possible Causes Effects
Liver Disease Liver dysfunction impairs ammonia processing.
Genetic Urea Cycle Disorders Inherited conditions disrupt ammonia elimination.
Kidney Disease Impairs urea excretion, affecting ammonia levels.
Reye Syndrome Rare but serious condition affecting children.

High ammonia levels in the blood may be caused by liver disease, genetic urea cycle disorders, kidney disease, or Reye Syndrome in children.

 

Ammonia Test Low Levels

Here are some possible causes of low ammonia levels:

Possible Causes Effects
Rare Genetic Conditions Urea cycle defects can lead to low ammonia levels.
Severe Liver Dysfunction Severe liver impairment can limit ammonia production.
Gastrointestinal Issues Malabsorption and gut problems may reduce ammonia.
Medications Certain drugs can affect ammonia metabolism.

Low ammonia levels may result from rare genetic conditions, severe liver dysfunction, gastrointestinal issues, or specific medications that affect ammonia metabolism.

 

Specimen Requirements For Ammonia Test

Here are the specimen requirements for the Ammonia Test.

Specimen

Plasma

Volume

1 ml

Container

Lavender-top (EDTA) tube; EDTA is the only acceptable anticoagulant.

Collection

Fill and seal tube tightly; place on ice. Separate plasma quickly. Avoid contamination. Use separate frozen samples for multiple tests.

Storage

Freeze

Sample Stability

Temperature

Period

Room temperature

Unstable 

Refrigerated

2 hours

Frozen

3 days

Freeze/thaw cycles

Unstable 

Causes for Rejection

Causes for issues: hemolysis, wrong anticoagulants, serum samples, lipemia.

 

Ammonia Test is Safe?

Ammonia tests are generally safe.

  • Risks primarily involve the blood draw process.
  • Minimal risk if performed by a trained professional.
  • Minor discomfort or bruising at the needle site is possible.
  • Discuss any concerns with your healthcare provider.

 

When Do You Get Ammonia Test Results? 

  • Ammonia test results are typically available within twenty four hours.
  • Faster results might be available for urgent cases.
  • The exact turnaround time can vary by the testing facility.
  • Your healthcare provider will communicate the results to you.

 

Ammonia Test Limitation

Here is the basic limitation of Ammonia Test.

  • Results vary with age.
  • Possible issues due to improper handling.
  • Limited as a standalone diagnostic tool.
  • High ammonia levels may have various causes.
  • Further testing often required for accurate diagnosis.

 

Ammonia Test Risk Factors

Here are some of the risk factors of the Ammonia Test.

  • Hemolysis increases ammonia.
  • Specimen handling issues affect results.
  • Anticoagulant type impacts accuracy.
  • Lipemia may interfere with testing.
  • Serum samples have variable values.

 

Doctor Recommendations After Ammonia Test Result

 Here are the Doctor's recommendations or consult a specialist after the Ammonia Test.

Test Result Doctor to Visit Reason to Go
High Gastroenterologist Liver disease.
Normal No specific doctor Routine check.
Low General practitioner Rare; further evaluation.

 

Ammonia Test Price

Here are the estimated Ammonia Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

400-800

New Delhi

480-800

Bangalore

400-800

Hyderabad

480-800

Kolkata

400-800

Pune

480-800

Lucknow

400-800

Noida

480-800

Surat

480-800

Gurugram

400-800

Patna

480-800

Chennai

400-800

Jaipur

480-800

Ahmedabad

400-800

*Prices are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall, Ammonia Test assesses blood ammonia levels, aiding in diagnosing liver and genetic conditions, with results indicating potential health issues. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • Ammonia - Wikipedia [1].
  • Ammonia blood test - UCSF [2].
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Ammonia Test FAQ

What is ammonia test for?

Ammonia tests measure blood ammonia levels, assessing liver function and detecting disorders such as hepatic encephalopathy, where the liver struggles to process ammonia.

What is high ammonia levels?

Elevated ammonia levels in the blood indicate potential liver dysfunction, which can lead to neurological issues. Monitoring these levels is crucial for patient health.

Why is ammonia tested on ice?

Ammonia is tested on ice to prevent its volatilization. Cold temperatures reduce evaporation, ensuring accurate measurements and reliable assessment of blood ammonia levels.

What does ammonia do in the body?

Ammonia is a byproduct of protein metabolism. In excess, it becomes toxic, affecting the central nervous system. The liver usually converts ammonia to urea for safe excretion.

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