The low globulin ratio refers to an abnormal imbalance between albumin and globulin levels in the blood. The ratio is calculated by dividing the albumin level by the globulin level. A low globulin ratio can indicate specific medical conditions, such as chronic liver disease, nephrotic syndrome, or certain autoimmune disorders. However, the interpretation of the ratio requires further evaluation in conjunction with other clinical findings to determine the underlying cause and appropriate treatment. Consulting a healthcare professional is essential for accurate diagnosis and management.