Vitamin B12 Test For Anemia and Deficiency

Vitamin B12 Test For Anemia and Deficiency

The vitamin B12 test is used to measure the level of that vitamin B12 in a person's blood. Vitamin B12 testing is used to find out if your body is not getting enough Vitamin B12 (vitamin B12 deficiency). A vitamin B12 and folate test is often used to check for certain types of anemia.

 

Vitamin B12 Test

Here is basic information about Vitamin B12 Test.

Also Known As Vitamin B Test, B12 Test
Type Blood Test
Purpose
Check Vitamin B12 Levels
Sample Type Blood
Preparation No Special Preparation Required
Gender Unisex
Age-Group Above 10 Years
Fasting No
Normal Value 200 - 900 pg/mL
Reporting Time 3 - 4 hrs
Cost 400 - 1200* INR

*Price range may vary as per location, lab type, and procedure of lab test.

 

Vitamin B12 Test Full Form

The Full form of Vitamin B12 Test is Vitamin Cobalamin Test where 12 Represents Cobalamin.

 

What is Vitamin B12 Test

The vitamin B12 test is a blood test that measures the level of Vitamin B12 in the blood.

  • Vitamin B12 is an important nutrient that is necessary for the normal functioning of the nervous system, the formation of red blood cells, and the synthesis of DNA.
  • A deficiency in Vitamin B12 can lead to a range of health problems, such as anemia, fatigue, weakness, tingling sensation in the fingers and toes, and memory problems.
  • The test is usually ordered by a doctor if a patient is experiencing symptoms of Vitamin B12 deficiency or if they have a condition that affects the absorption of Vitamin B12, such as pernicious anemia or Crohn's disease.
  • The test involves taking a blood sample from a vein in the arm, and the results are usually available within a few days.
  • The normal range for Vitamin B12 levels varies between different labs, but a level below 200 pg/mL is generally considered to be low and may indicate a deficiency.

Interesting Facts About Vitamin B12

  • Vitamin B12, also known as cobalamin, is an essential nutrient.
  • It plays a crucial role in the production of red blood cells and DNA.
  • Vitamin B12 is primarily found in animal-based foods like meat, fish, eggs, and dairy products.
  • Deficiency of vitamin B12 can lead to anemia, neurological symptoms, and fatigue.
  • Vitamin B12 is not naturally produced by the body and must be obtained through diet or supplements.

 

Vitamin B12 Test Purpose

The purpose of a Vitamin B12 test is to measure the level of Vitamin B12 in the blood.

  • The test is usually done to diagnose or monitor a Vitamin B12 deficiency.
  • It can also help diagnose the cause of anemia, neuropathy, or other neurological symptoms.
  • The test may be ordered as part of a routine check-up or for people who have conditions that affect Vitamin B12 absorption, such as Crohn's disease or pernicious anemia.
  • Vitamin B12 testing can help doctors determine the appropriate treatment for a Vitamin B12 deficiency, which may include Vitamin B12 supplements or changes in diet.

 

Vitamin B12 Test Price Normal Range Results Purpose Meaning and Interpretation - Drlogy Test

 

Vitamin B12 Test Preparation

Here are the preparations for the Vitamin B12 test.

 

Before the test:

  • Inform your doctor about any medications, vitamins, or supplements you are taking.
  • Fasting is not required for the test, but you should follow any specific instructions given by your doctor.

 

During the test

  • The test involves taking a blood sample from a vein in your arm.
  • The healthcare provider may use a tourniquet to make the veins more visible, and then clean the area with an antiseptic.

 

After the test:

  • After the blood sample is taken, a bandage will be placed on the area where the needle was inserted.
  • You can resume your normal activities right away, and there are no restrictions on your diet or activities.

Summary

For a Vitamin B12 test, inform your doctor about medications, a blood sample is taken, and there are no specific restrictions after the test.

 

Vitamin B12 Test Procedure

Here are the steps involved in the Vitamin B12 Test procedure:

  1. A healthcare professional will collect a blood sample from a vein in your arm using a small needle.
  2. The site will be cleaned with an antiseptic solution, and an elastic band will be wrapped around your upper arm to create pressure and cause the vein to swell with blood.
  3. The needle will be inserted into the vein and the blood will be collected in a tube attached to the needle.
  4. Once the blood is collected, the healthcare professional will remove the needle and place a small bandage or cotton ball over the site to stop any bleeding.
  5. The blood sample will be sent to a laboratory for analysis, and the results will be communicated to your healthcare provider.

 

Vitamin B12 Test Result

  • The Vitamin B12 test result will show the level of Vitamin B12 in your blood in picograms per milliliter (pg/mL) or picomoles per liter (pmol/L).
  • The normal range for Vitamin B12 levels in the blood is typically between 200 and 900 pg/mL (or 148 to 664 pmol/L).
  • Results outside of the normal range may indicate a deficiency or excess of Vitamin B12 in the body and should be interpreted by a medical professional.

 

Vitamin B12 Test Report

Vitamin B12 Test Report - Drlogy Test

Vitamin B12 Test Report PDF

 

Vitamin B12 Test Normal Report

Vitamin B12 Test Normal Report Format Example Sample Template - Drlogy Pathology Lab Report Format

Vitamin B12 Normal Test Report PDF Format

Vitamin B12 Test Normal Result Report PDF

 

Vitamin B12 Test Abnormal Report

Vitamin B12 Test Abnormal Report Format Example Sample Template - Drlogy Pathology Lab Report Format

Vitamin B12 Abnormal Test Report PDF Format

Vitamin B12 Test Abnormal Result Report PDF

 

Vitamin B12 Test Normal Range

The normal range of Vitamin B12 may vary slightly depending on the laboratory and the measurement units used.

However, below is an example of the normal range for Vitamin B12 in the commonly used units:

Measurement Units Normal Range
pg/mL (picograms per milliliter) 200-900
pmol/L (picomoles per liter) 148-664

It's important to note that the reference range may differ between labs and it's best to consult with your healthcare provider to interpret your Vitamin B12 test results.

 

Vitamin B12 Test Interpretation

Here's an example table for interpreting Vitamin B12 test results:

Vitamin B12 Test Result Interpretation Serum B12 Level
Deficiency < 200 pg/mL
Possible deficiency 200-300 pg/mL
Normal 300-900 pg/mL
High > 900 pg/mL

Note: This is just an example and reference ranges may vary depending on the laboratory and testing method used. It is important to consult with a healthcare provider.

 

Specimen Requirments For Vitamin B12 Test

Here are the specimen requirements for Vitamin B12 Test.

Specimen Whole Blood
Volume 1.6 ml
Container Lavender-top (EDTA) microcollection tube

 

Vitamin B12 Test High Levels

Here are the causes of high Vitamin B12 levels:

Cause Explanation
Liver disease The liver stores and releases Vitamin B12, so any damage or disease that affects the liver can cause it to release more Vitamin B12 into the bloodstream, leading to high levels.
Leukemia Some types of leukemia can cause the body to produce too many red blood cells, which can lead to high levels of Vitamin B12.
Polycythemia vera This is a rare blood disorder in which the bone marrow produces too many red blood cells, leading to high levels of Vitamin B12.
Hypereosinophilic syndrome This is a rare disorder in which the body produces too many eosinophils, a type of white blood cell, leading to high levels of Vitamin B12.
Chronic myeloid leukemia This is a type of cancer that affects the bone marrow and leads to high levels of Vitamin B12.
Excessive supplementation Taking too many Vitamin B12 supplements can lead to high levels in the bloodstream.
Other causes High levels of Vitamin B12 can also be caused by other factors, such as kidney disease, certain medications, or certain genetic conditions.

 

Vitamin B12 Test Low Levels

Here are the causes of low vitamin B12 levels:

Causes of Low Vitamin B12 Description
Pernicious Anemia A type of anemia caused by a lack of intrinsic factor, a protein made by the stomach that helps in vitamin B12 absorption
Inadequate Dietary Intake Low intake of vitamin B12-rich foods, such as meat, dairy, and eggs
Malabsorption The body's inability to absorb vitamin B12 properly, which can be caused by gastrointestinal disorders such as Crohn's disease, celiac disease, or bacterial overgrowth in the intestines
Medications Some medications, such as metformin, proton pump inhibitors, and histamine blockers, can interfere with vitamin B12 absorption
Surgery Some types of gastrointestinal surgeries can reduce the body's ability to absorb vitamin B12
Parasitic Infections Parasitic infections such as tapeworms can lead to a deficiency in vitamin B12
Chronic Alcoholism Excessive alcohol consumption can interfere with vitamin B12 absorption and increase the risk of deficiency
Pregnancy and Breastfeeding Pregnant and breastfeeding women require more vitamin B12, and a deficiency in these periods can lead to developmental problems in the fetus or infant

Summary

High Vitamin B12 levels can be associated with certain medical conditions or excessive supplementation, while low levels may indicate a deficiency, which can lead to anemia or neurological symptoms.

 

Vitamin B12 Test is Safe?

  • The Vitamin B12 test is generally considered safe and non-invasive.
  • It involves a simple blood test, which is a routine procedure and carries a low risk of complications.
  • However, as with any medical test, there may be a slight risk of infection, bleeding, or bruising at the site where the blood is drawn.

 

When Do You Get Vitamin B12 Test Results?

  • The turnaround time for a Vitamin B12 test result may vary depending on the laboratory or clinic that performs the test.
  • In general, you can expect to receive the results within 3 - 4 hrs after the test has been performed.

 

Vitamin B12 Test Limitation

Here are some possible limitations of the Vitamin B12 Test.

  • Inability to determine functional deficiency.
  • False-normal results in the presence of inactive B12 analogs.
  • Limited specificity in differentiating between causes of deficiency.
  • May not reflect tissue or cellular B12 levels accurately.
  • Insufficient in diagnosing functional B12 deficiency in certain cases.

 

Vitamin B12 Test Risk Factors

Here is the potential risk factor of the Vitamin B12 Test.

  • Inadequate dietary intake of vitamin B12.
  • Certain medical conditions affecting absorption, such as pernicious anemia.
  • Gastrointestinal surgeries or disorders affecting the absorption of vitamin B12.
  • Use of certain medications that can interfere with vitamin B12 absorption.
  • Vegetarian or vegan diets lacking animal-based sources of vitamin B12.

 

Doctor Recommendations After Vitamin B12 Test Result

Here are Doctor recommendations or consult a specialist after Vitamin B12 Test.

Vitamin B12 Test Result Doctor to Visit Reason to Visit
High Primary Care Physician Further evaluation and guidance
Normal No immediate visit Maintain healthy lifestyle
Low Primary Care Physician Identify and treat deficiency

 

Vitamin B12 Test Price

Here are the estimated Vitamin B12 Test Price in India with different top cities:

City Price Range (INR)*
Mumbai 400 - 1200
New Delhi 600 - 1200
Bangalore 400 - 1200
Hyderabad 600 - 1200
Kolkata 400 - 1200
Pune 600 - 1200
Lucknow 600 - 1200
Noida 400 - 1200
Surat 600 - 1200
Gurugram 400 - 1200
Patna 600 - 1200
Chennai 400 - 1200
Jaipur 600 - 1200
Ahmedabad 400 - 1200

*Prices are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall, Vitamin B12 Test. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • Vitamin B12 - Wikipedia [1].
  • Vitamin B12 Deficiency Anemia [2].

 

 

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Vitamin B12 Test FAQ

What is the test of vitamin B12?

A Vitamin B12 test is a blood test that measures the levels of Vitamin B12 in the body.

  • Vitamin B12 is an essential nutrient that plays a crucial role in the production of red blood cells, nerve function, and DNA synthesis.
  • The test helps to assess Vitamin B12 deficiency or monitor the effectiveness of treatment for Vitamin B12 deficiency.

What do the results of a Vitamin B12 test mean?

The results of the Vitamin B12 test are interpreted based on the reference range provided by the laboratory.

  • Normal levels of Vitamin B12 typically range from 200-900 picograms per milliliter (pg/mL) or 148-664 picomoles per liter (pmol/L).
  • Low levels of Vitamin B12 may indicate a deficiency, which can be caused by dietary deficiencies, malabsorption, certain medications, or underlying health conditions.
  • High levels of Vitamin B12 are less common but may occur in certain liver diseases or due to excessive supplementation.
  • It's important to consult with a healthcare provider to interpret the results and determine the appropriate course of action if the Vitamin B12 levels are abnormal.

Which fruit is rich in vitamin B12?

Vitamin B12 is primarily found in animal-derived foods, and fruits are generally not significant sources of this vitamin. However, certain fermented fruits, like purple laver or nori, which are commonly used in making sushi, can contain traces of vitamin B12. It's important to note that the B12 content in these fruits can be variable, and they are not reliable sources of the vitamin. If you're looking to increase your B12 intake, it's advisable to focus on animal products such as meat, fish, eggs, and dairy, or consider fortified plant-based products or B12 supplements.

What are the 4 stages of B12 deficiency?

Vitamin B12 deficiency progresses through four stages: Stage 1 (marginal deficiency) involves lower-than-normal B12 levels in the blood, but often no apparent symptoms. Stage 2 (mild deficiency) may present with nonspecific symptoms such as fatigue, weakness, and difficulty concentrating. Stage 3 (moderate deficiency) exhibits more pronounced symptoms, including anemia, neurological issues like numbness or tingling, memory problems, and mood changes. Stage 4 (severe deficiency) is characterized by severe anemia, neurological symptoms such as difficulty walking, significant memory impairment, and potentially irreversible nerve damage. Prompt diagnosis and treatment in the earlier stages are crucial to prevent progression to severe deficiency and irreversible complications. If you suspect a B12 deficiency or experience related symptoms, consult with a healthcare professional for evaluation and appropriate management.

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