Syphilis Test To Screen for and Diagnose Syphilis

Syphilis Test To Screen for and Diagnose Syphilis

A syphilis test is a medical examination to check for a sexually transmitted disease called syphilis, ensuring early detection and treatment. It's crucial for maintaining sexual health and preventing potential complications.

 

Syphilis Test

Here are the basic details of the Syphilis Test.

Also Known As Syphilis Serology Test
Type Blood Test
Purpose To detect and diagnose syphilis infection
Sample Type Serum
Preparation No
Fasting No
Gender Unisex
Age Group All
Normal Value Negative
Reporting Time A few hours to several days
Cost 700-1500 INR*

*Price range may vary as per location, lab type, and procedure of lab test.

 

Syphilis Test Means

Syphilis test is a diagnostic procedure used to identify the presence of Treponema pallidum antibodies, indicating a syphilis infection.

  • Syphilis test aims to diagnose and confirm syphilis, a sexually transmitted infection caused by the bacterium T. pallidum.
  • Typically, a syphilis test requires a blood sample, either serum or plasma, for laboratory analysis.
  • Early detection through syphilis testing is crucial to initiate timely treatment and prevent the disease's complications.
  • It's a non-invasive test, usually involving a simple blood draw without the need for fasting or special preparation.
  • Syphilis tests have a high level of accuracy in identifying the presence of antibodies produced in response to the infection.
  • Syphilis testing is often part of routine sexual health screenings for individuals at risk of infection or those with potential exposure to the disease.

 

Syphilis Test Types

Syphilis Test Type Sub Type
Nontreponemal Tests RPR, VDRL, rapid plasma reagin
Treponemal Tests TP-PA, EIAs, Chemiluminescence

 

Syphilis Test Purpose

The purpose of the Syphilis Test is to:

  • Detect syphilis infection.
  • Confirm presence of Treponema pallidum antibodies.
  • Early diagnosis for timely treatment.
  • Part of routine sexual health screenings.
  • Ensure accurate detection of syphilis in at-risk individuals.

Syphilis Test_ Price, Normal Range, Result, Purpose, Meaning and Interpretation - Drlogy Test

 

Syphilis Test Preparation

Here is the basic preparation for the Syphilis Test.

 

Before Test

  • No fasting or dietary restrictions are necessary.
  • Inform your healthcare provider about any medications or allergies.
  • Be prepared for a simple blood draw during the test.

 

During Test

  • A healthcare professional will collect a blood sample.
  • The procedure is usually quick and minimally uncomfortable.
  • Stay relaxed and follow the healthcare provider's instructions.

 

After Test

  • You can resume your normal activities immediately.
  • There's no specific post-test care required.
  • Await the test results, typically available within a few days.

 

Syphilis Test Procedure

Here is the basic Syphilis Test Procedure.

  • Blood sample collected from arm.
  • Sample sent to lab for analysis.
  • Detects Treponema pallidum antibodies.
  • Results available in a few days.
  • Consult healthcare provider for interpretation.

 

Syphilis Test Result

  • Positive nontreponemal test: Possible syphilis, confirm with treponemal test.
  • Negative result: Likely no syphilis, further testing for symptoms may be necessary.
  • Treponemal test: Positive confirms syphilis, negative suggests no current infection.

 

Syphilis Test Normal Range

Here is the normal range of the Syphilis Test.

Syphilis Test Normal Range
VDRL Test 85% - 99%
TPHA Test - (Negative) to 4+ (Strong Positive)

 

Syphilis Test Interpretation

Here is the Interpretation of the Syphilis Test.

Syphilis Test Interpretation
Nontreponemal Test (e.g., VDRL) Positive: Suggests possible syphilis; confirm with treponemal test. Negative: Likely no syphilis; further testing if symptoms persist.
Treponemal Test (e.g., TPHA) Positive: Confirms syphilis infection. Negative: Suggests no current syphilis infection.

Syphilis test, Positive nontreponemal suggests possible syphilis, confirmed by treponemal; negative indicates likely no infection.

 

Syphilis Test Positive

Here are some possible causes of positive Syphilis test.

Possible Causes Effects
Syphilis infection Indicates an active infection.
Previous syphilis infection Residual antibodies from past infection.
Cross-reactivity Antibodies from other conditions.
False-positive result Lab error or interference.

A positive syphilis test result may indicate an active infection, previous infection, cross-reactivity, or a possible false positive.

 

Syphilis Test Negative

Here are some possible causes of negative Syphilis test.

Possible Causes Effects
No syphilis infection Absence of Treponema pallidum antibodies.
Early-stage infection Antibodies not yet detectable.
Lab error or testing limitations False-negative result due to various factors.

A negative syphilis test result may indicate no infection, an early-stage infection, or false-negative results due to testing factors.

 

Specimen Requirements For Syphilis Test

Here are the specimen requirements for the Syphilis Test.

Specimen

Serum

Volume

2 ml

Container

Red-top tube or gel-barrier tube

Storage

Room temperature.

Sample Stability

Temperature

Period

Room temperature

14 day

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Hemolysis; lipemia; gross bacterial contamination; plasma specimen

 

Syphilis Test is Safe?

Syphilis tests are generally safe.

  • They involve a simple blood draw.
  • Minimal discomfort and no major risks.
  • Standard procedures in healthcare.

 

When Do You Get Syphilis Test Results? 

  • Syphilis test results typically within a few hours to several days.
  • Rapid tests may offer results in minutes.
  • Laboratory tests may take slightly longer.
  • Confirmatory tests may require additional time.

 

Syphilis Test Limitation

Here is the basic limitation of Syphilis Test.

  • Early-stage infections may yield false-negative results.
  • Cross-reactivity with other conditions can occur.
  • Interpretation errors may lead to misdiagnosis.
  • Laboratory errors or contamination may affect accuracy.
  • Sensitivity and specificity can vary among different tests.

 

Syphilis Test Risk Factors

Here are some of the risk factors of the Syphilis Test.

  • Unprotected sexual intercourse with an infected partner.
  • Multiple sexual partners or high-risk sexual behaviors.
  • Previous history of syphilis or other STIs.
  • Men who have sex with men (MSM) are at higher risk.
  • Living in an area with high syphilis prevalence.

 

Doctor Recommendations After Syphilis Test Result

 Here are the Doctor's recommendations or consult a specialist after the Syphilis Test.

Syphilis Test Result Doctor to Consult Reason
Positive Infectious Disease Treatment and counseling.
Negative Primary Care Doctor Discuss results & care.

Consult an infectious disease specialist for positive results and discuss negative results with your primary care doctor for guidance.



Syphilis Test Price

Here are the estimated Syphilis Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

700-1500

New Delhi

750-1500

Bangalore

700-1500

Hyderabad

750-1500

Kolkata

700-1500

Pune

750-1500

Lucknow

700-1500

Noida

750-1500

Surat

750-1500

Gurugram

700-1500

Patna

750-1500

Chennai

700-1500

Jaipur

750-1500

Ahmedabad

700-1500

*Prices are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall, Syphilis tests, crucial for sexual health, detect infections and inform treatment decisions, ensuring early intervention and prevention. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • Syphilis - Wikipedia [1].
  • Syphilis Test - NIH [2].

 

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Syphilis Test FAQ

What is the best test to confirm syphilis?

Treponemal tests such as TP-PA (Treponema pallidum particle agglutination) or FTA-ABS (Fluorescent Treponemal Antibody Absorption) are considered more specific for confirming syphilis.

What is a VDRL test for syphilis?

VDRL (Venereal Disease Research Laboratory) is a non-treponemal test that detects antibodies produced in response to syphilis infection. It's used for screening, but false positives may occur.

What are the three tests for syphilis?

1. VDRL (non-treponemal screening) 2. TP-PA (treponemal confirmatory) 3. FTA-ABS (treponemal confirmatory)

Can doctors detect syphilis?

Yes, doctors can detect syphilis through various tests, including blood tests like VDRL, TP-PA, and FTA-ABS, which identify antibodies produced in response to the syphilis bacterium.

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