Protein C and Protein S Test For Blood Clotting Disorders

Protein C and Protein S Test For Blood Clotting Disorders

The Protein C and Protein S tests are blood tests that assess the levels and activity of two important proteins involved in blood clotting. They help diagnose and evaluate conditions associated with an increased risk of abnormal blood clot formation, such as deep vein thrombosis and clotting disorders.

 

Protein C and Protein S Test

Here are the basic details of the Protein C and Protein S Test.

Also Known As Protein C Level, Protein S Level
Type Blood test
Purpose Evaluate blood clotting risk
Sample Type Blood
Preparation Typically none required
Fasting Fasting not typically needed
Gender All
Age Group All
Normal Value
  • 0.72 to 1.23 U/ml
  • 0.60to 1.60 U/ml
Reporting Time Few Days
Cost 1500-4000 INR*

*Protein C and Protein S Test Price range may vary as per location, lab type, and procedure of lab test.

 

Protein C and Protein S Test Means

Protein C and Protein S Test Blood test evaluating proteins related to clotting.

  • Identifies risks of abnormal blood clot formation.
  • Useful for diagnosing clotting disorders.
  • Gender and age group agnostic.
  • Helps determine thrombosis risk.
  • No fasting or specific preparation needed.

 

Protein C and Protein S Test Purpose

The purpose of the Protein C and Protein S Test is to:

  • Blood test evaluating proteins related to clotting.
  • Identifies risks of abnormal blood clot formation.
  • Useful for diagnosing clotting disorders.
  • Gender and age group agnostic.
  • Helps determine thrombosis risk.
  • No fasting or specific preparation needed.

Protein C and  Protein S Test- Price, Normal Range, Result, Purpose, Procedure Meaning and Interpretation - Drlogy Tests

 

Protein C and Protein S Test Preparation

Here is the basic preparation for the Protein C and Protein S Test.

 

Before Test

  • No specific dietary restrictions or fasting are typically needed.
  • Inform your healthcare provider about any medications or supplements you're taking.

 

During Test

  • A blood sample will be drawn from a vein in your arm.
  • The blood sample is sent to the laboratory for analysis of protein C and protein S levels.

 

After Test

  • You can resume normal activities immediately.
  • Monitor the puncture site for any signs of bleeding or infection.
  • Await test results, and follow up with your healthcare provider for interpretation and guidance as necessary.

 

Protein C and Protein S Test Procedure

Here is the basic Protein C and Protein S Test Procedure.

  • A blood sample is taken from a vein in your arm.
  • The sample is sent to the laboratory for analysis.
  • The levels of protein C and protein S are measured.
  • Results are shared by your healthcare provider.

 

Protein C and Protein S Test Result

Here is basic meaning of Protein C and Protein S Test.

  • Normal results fall within a laboratory-specific reference range.
  • Abnormal levels may suggest a risk of abnormal blood clotting.
  • Interpretation should be done in consultation with a healthcare provider, considering your medical history.
  • Follow-up testing or treatments may be recommended based on the results.

 

Protein C and Protein S Test Normal Range

Here is the normal range of the Protein C and Protein S Test.

Protein Component Normal Range 
Protein C 0.72 to 1.23 U/ml
Protein S 0.60 to 1.60 U/ml

 

Protein C and Protein S Test Interpretation

Here is the Interpretation of the Protein C and Protein S Test.

Protein Component Interpretation
Protein C Low levels may indicate a deficiency, increasing the risk of abnormal blood clotting (thrombosis).
Protein S Low levels may indicate a deficiency, increasing the risk of abnormal blood clotting (thrombosis).

 

Protein C and Protein S Test High Levels

Here are the potential causes of Protein C and Protein S Test High Levels.

Potential Causes Information
Rare Genetic Conditions Hereditary factors may lead to elevated protein C and S levels.
Blood Disorders Certain blood disorders, like polycythemia, may increase these protein levels.
Pregnancy Pregnancy can lead to temporary increases in protein C and S levels.
Medications Specific medications or treatments may result in higher protein levels.

 

Protein C and Protein S Test Low Levels

Here are the potential causes of Protein C and Protein S Test Low Levels.

Potential Causes Information
Genetic Deficiency Inherited deficiencies in protein C or S can lead to low levels and an increased risk of clotting disorders.
Liver Disease Liver dysfunction can impact the production of these proteins, leading to lower levels.
Vitamin K Deficiency Inadequate vitamin K, necessary for protein C and S, can result in reduced levels.
Blood Clotting Disorders Conditions that promote excessive clotting may deplete protein C and S levels.

 

Specimen Requirements For Protein C and Protein S Test

Here are the specimen requirements for the Protein C and Protein S Test.

Specimen

Serum

Volume

1 ml

Container

Sterile blood collection tube (lavender top for citrate anticoagulant)

Collection

Venipuncture by a healthcare professional. Invert the tube several times to mix the anticoagulant.

Storage

Store at room temperature (RT) and deliver to the laboratory promptly.

Sample Stability

Temperature

Period

Room temperature

7 days

Refrigerated

14 days

Frozen

60 days

Freeze/thaw cycles

Stable x1

Causes for Rejection

Hemolysis, clotted sample, insufficient volume, incorrect container (non-sterile).

 

Protein C and Protein S Test is Safe?

Protein C and Protein S Test is a safe blood test with minimal risks.

  • Risks are associated with the blood draw.
  • Generally considered safe for diagnostic purposes.

 

When Do You Get Protein C and Protein S Test Results? 

  • Typically, Protein C and Protein S Test results comes within a few days.
  • The exact timing may depend on the laboratory and healthcare provider.

 

Protein C and Protein S Test Limitation

Here is the basic limitation of Protein C and Protein S Test.

  • Results can be influenced by medications, recent surgeries, or acute illnesses.
  • Test results may not always reflect a person's long-term clotting risk.
  • Genetic variations can affect protein C and protein S levels, leading to variability in test results.
  • The test may not detect all potential clotting disorders.
  • Abnormal results may necessitate additional testing for precise diagnosis and risk assessment.

 

Protein C and Protein S Test Risk Factors

Here are some of the risk factors of the Protein C and Protein S Test.

  • Results can be influenced by medications, recent surgeries, or acute illnesses.
  • Genetic variations can affect protein C and protein S levels, leading to variability in test results.
  • Limited to assessing clotting risk and not diagnosing specific diseases.
  • Test results may not always reflect a person's long-term clotting risk.
  • Abnormal results may require further testing for precise diagnosis and risk assessment.

 

Doctor Recommendations After Protein C and Protein S Test Result

 Here are the Doctor's recommendations or consult a specialist after the Protein C and Protein S Test.

Test Results Doctor to Consult Reason to Visit
High Hematologist Evaluate potential underlying conditions.
Low Hematologist Assess clotting risk and discuss treatment.
Normal No immediate need Follow up based on clinical history.

 

Protein C and Protein S Test Price

Here are the estimated Protein C and Protein S Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

1500-4000

New Delhi

2000-4000

Bangalore

1500-4000

Hyderabad

2000-4000

Kolkata

1500-4000

Pune

2000-4000

Lucknow

1500-4000

Noida

2000-4000

Surat

2000-4000

Gurugram

1500-4000

Patna

2000-4000

Chennai

1500-4000

Jaipur

2000-4000

Ahmedabad

1500-4000

*Prices are approximate and vary depending on a specific laboratory or healthcare facility.

 

 

Summary

Overall, Protein C and Protein S Test evaluates clotting risks and detects clotting disorders, helping to mitigate thrombosis risk and determine appropriate interventions. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • Protein C and Protein S Test - Wikipedia [1].
  • Protein S (Blood) - Health Encyclopedia - URMC [2].

 

 

 

 

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Protein C And Protein S Test FAQ

What is Protein C and Protein S?

Protein C and Protein S are essential blood proteins involved in regulating blood clotting. Protein C is a natural anticoagulant that helps prevent excessive blood clotting, while Protein S acts as a cofactor for Protein C, enhancing its anticoagulant effects. Both play crucial roles in maintaining a balance between clotting and bleeding.

Why are Protein C and Protein S tests done?

These tests are typically performed to assess the risk of abnormal blood clot formation. They can help diagnose conditions such as deep vein thrombosis (DVT), pulmonary embolism, and thrombophilia. Testing is also crucial for understanding the risk of clotting disorders in patients.

Can I get Protein C and Protein S tests done at home?

Some at-home test kits for Protein C and Protein S are available. However, it's important to consult with a healthcare provider to ensure the accuracy and reliability of these tests. In some cases, healthcare providers may prefer in-person testing in a clinical setting.

Are Protein C and Protein S tests painful?

The tests themselves are not painful. A healthcare professional will draw a blood sample, which may cause a momentary discomfort similar to a quick pinprick. The discomfort is usually minimal and short-lived.

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