Phenobarbital Test For Epilepsy

Phenobarbital Test For Epilepsy

Phenobarbital Test measures drug levels in the blood to ensure proper dosing for epilepsy control and prevent side effects like seizures or drowsiness.

 

Phenobarbital Test

Here are the basic details of the Phenobarbital Test.

Also Known As Phenobarbital Drug Monitoring
Type Blood Test
Purpose Monitor and adjust epilepsy treatment to prevent seizures
Sample Type Serum or plasma
Preparation No
Fasting Not required
Gender Unisex
Age Group All
Normal Value 15.00-40.00 ug/mL
Reporting Time 2 days
Cost 400-1200 INR*

*Price range may vary as per location, lab type, and procedure of lab test.

 

Phenobarbital Test Means

The Phenobarbital Test checks blood levels of the medication phenobarbital.

  • Ensures effective epilepsy treatment and prevents seizures and side effects.
  • Helps in adjusting medication dosages for optimal results.
  • Vital for those with epilepsy to maintain controlled and healthy lives.
  • A key diagnostic tool for epilepsy management.

 

Phenobarbital Test Purpose

The purpose of the Phenobarbital Test is to:

  • Monitors drug levels in the blood to effectively manage epilepsy, reducing the risk of seizures.
  • Ensures that the medication is within the therapeutic range, preventing both underdosing and side effects.
  • Tailors treatment for individual patients, maintaining their well-being.
  • Crucial for preventing epileptic seizures and ensuring a better quality of life.
  • Offers insights into the effectiveness of phenobarbital treatment, guiding adjustments for optimal results.

Phenobarbital Test- Price, Normal Range, Result, Purpose, Procedure Meaning and Interpretation - Drlogy Test

 

Phenobarbital Test Preparation

Here is the basic preparation for the Phenobarbital Test.

 

Before Test

  • Follow your healthcare provider's instructions for any specific preparation.
  • Inform your healthcare provider about all medications and supplements you are taking.
  • Ensure you are well-hydrated before the test.

 

During Test

  • A blood sample will be collected from a vein in your arm or hand using a needle.
  • You may feel a slight sting or pain when the needle is inserted.

 

After Test

  • You can resume your regular activities and diet.
  • Follow up with your healthcare provider to discuss the test results.
  • It might be required any necessary medication adjustments.

 

Phenobarbital Test Procedure

Here is the basic Phenobarbital Test Procedure.

  • Blood samples are collected from a vein in your arm or hand using a needle.
  • The sample is analyzed to measure phenobarbital levels.
  • Results guide medication dosing and adjustments for epilepsy management.

 

Phenobarbital Test Result

  • Phenobarbital concentration in mcg/mL.
  • Within the therapeutic range: effective treatment.
  • Above or below range may require dose adjustments.

 

Phenobarbital Test Abnormal Result Report

Phenobarbital Test Abnormal Result Report Format

Phenobarbital Test Abnormal Report (High Levels):

Phenobarbital Test Abnormal Result Report

 

Phenobarbital Test Normal Result Report

Phenobarbital Test Normal Result Report Format - Drlogy Test Report

Phenobarbital Test Normal Report:

Phenobarbital Test Normal Result Report

 

Phenobarbital Test Normal Range

Here is the normal range of the Phenobarbital Test.

Test Normal Range
Phenobarbital Test 15.00-40.00 ug/mL

 

Phenobarbital Test Interpretation

Here is the Interpretation of the Phenobarbital Test.

Result Range Interpretation
15-40 ug/mL Therapeutic range
>40 ug/mL Toxic range

The test's therapeutic range guides epilepsy treatment, with toxic levels exceeding 40 ug/mL, considering medication interactions and age-dependent metabolism.

 

Phenobarbital Test High Levels

Here are the potential causes of high Phenobarbital Test levels:

Possible Causes Description
Overdose Excessive intake of the medication
Medication Interactions Interference with other drugs
Impaired Metabolism Reduced clearance due to organ dysfunction
Age-Related Metabolism Changes Altered metabolism in the elderly

High Phenobarbital levels are attributed to overdose, medication interactions, impaired metabolism, and age-related changes in metabolism.

 

Phenobarbital Test Low Levels

Here are the potential causes of low Phenobarbital Test levels:

Possible Causes Description
Underdosing Inadequate medication intake
Medication Interactions Competing with other drugs
Impaired Elimination Reduced drug clearance due to organ dysfunction
Age-Related Metabolism Changes Altered metabolism in the elderly

Low Phenobarbital levels may result from underdosing, medication interactions, impaired elimination, or age-related metabolism changes.

 

Specimen Requirements For Phenobarbital Test

Here are the specimen requirements for the Phenobarbital Test.

Specimen

Serum or plasma

Volume

1 mL

Container

Red-top tube or green-top tube. Do not use a gel-barrier tube.

Collection

Transfer separated serum or plasma to a plastic transport tube. Peak: 4 to 12 hours after dose; trough: immediately prior to next dose.

Storage

Refrigerate or freeze.

Sample Stability

Temperature

Period

Room temperature

7 day

Refrigerated

14 days

Frozen

60 days

Freeze/thaw cycles

Stable x1

Causes for Rejection

Gel-barrier tube; hemolysis; severe lipemia; icteric specimen

 

Phenobarbital Test is Safe?

Phenobarbital Test is generally safe when performed by trained professionals.

  • May involve a blood draw, which carries minimal risks.
  • Results contribute to safe epilepsy management.
  • Follow the healthcare provider's guidance for safe use.

 

When Do You Get Phenobarbital Test Results? 

  • Turnaround time varies but is usually available within two days.
  • Results were discussed with the healthcare provider for treatment adjustments.

 

Phenobarbital Test Limitation

Here is the basic limitation of the Phenobarbital Test.

  • Variations in metabolism among individuals may affect accuracy.
  • Limited information on drug interactions or patient-specific factors.
  • Interpretation may require consideration of other clinical factors.
  • Results reflect a specific point in time, may vary over time.
  • Cannot provide information on the underlying cause of seizures.

 

Phenobarbital Test Risk Factors

Here are some of the risk factors of the Phenobarbital Test.

  • Other drugs may affect test accuracy, influencing epilepsy treatment decisions.
  • Metabolism and response to phenobarbital may vary with age, impacting dosage adjustments.
  • Impaired liver and kidney function can impact phenobarbital levels and effectiveness, requiring monitoring.
  • Inconsistent dosing can affect phenobarbital levels, potentially affecting seizure management.
  • Response to phenobarbital may vary among patients, influencing treatment effectiveness and safety.

 

Doctor Recommendations After Phenobarbital Test Result

 Here are the Doctor's recommendations or consult a specialist after the Phenobarbital Test.

Phenobarbital Test Result Doctor to Visit Reason to See Doctor
High Neurologist Adjust epilepsy treatment
Normal Primary Care Routine medication review
Low Healthcare Provider Discuss medication management



Phenobarbital Test Price

Here are the estimated Phenobarbital Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

400-1000

New Delhi

400-1200

Bangalore

400-1000

Hyderabad

400-1000

Kolkata

400-1000

Pune

400-1000

Lucknow

400-1000

Noida

400-1000

Surat

400-1000

Gurugram

400-1000

Patna

400-1000

Chennai

400-1000

Jaipur

400-1000

Ahmedabad

400-1000

*Prices are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall, Phenobarbital Test is a diagnostic test measuring phenobarbital levels in the blood, aiding in epilepsy management and treatment adjustment. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • Phenobarbital - Wikipedia [1].
  • Phenobarbital - NIH [2].

 

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Phenobarbital Test FAQ

What is a phenobarbital test?

A phenobarbital test is a blood test used to measure the concentration of phenobarbital in a person's blood.

What is phenobarbital used for?

Phenobarbital is a medication primarily used to treat seizures and epilepsy. It's a barbiturate sedative.

What is the protocol for phenobarbital blood test?

The protocol involves drawing a blood sample, typically in a lavender-top tube, and sending it to a lab for analysis.

What color tube is a phenobarbital test?

A lavender-top tube, often containing an EDTA anticoagulant, is commonly used for phenobarbital blood tests.

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