IGRA TB Test To Detect Tuberculosis Infection

IGRA TB Test To Detect Tuberculosis Infection

An IGRA TB test, or Interferon-Gamma Release Assay, is a blood test used to detect tuberculosis (TB) infection. It assesses the body's immune response to TB bacteria, aiding in the diagnosis of latent TB infection or active TB disease.

 

IGRA TB Test

Here are the basic details of the IGRA TB Test.

Also Known As TB Blood Test
Type Blood Test
Purpose Detect TB Infection
Sample Type Blood
Preparation No specific prep
Fasting Not necessary
Gender All
Age Group All ages
Normal Value Negative
Reporting Time Within 24 hrs
Cost 1500-4500 INR*

*Price range may vary as per location, lab type, and procedure of lab test.

 

IGRA TB Test Means

IGRA stands for Interferon-Gamma Release Assay, which is a type of blood test.

  • It is used to detect tuberculosis (TB) infection by measuring the body's immune response to the TB bacteria.
  • IGRA tests are more specific than the traditional TB skin test (TST) and less likely to give false-positive results.
  • They help diagnose latent TB infection (LTBI) in individuals at risk of TB, allowing for early treatment and prevention of active TB disease.
  • IGRA tests are commonly used in healthcare settings and for screening individuals who have had close contact with TB patients.
  • This test is crucial for TB control and prevention efforts, especially in populations at higher risk of TB exposure and infection.

 

IGRA TB Test Purpose

The purpose of the IGRA TB Test is to:

  • Detects tuberculosis (TB) infection.
  • Screens for latent TB.
  • Helps diagnose active TB disease.
  • Useful for individuals at risk of TB exposure.
  • Provides an alternative to the tuberculin skin test.
  • Helps with TB prevention and control efforts.

IGRA TB Test_ Price, Normal Range, Result, Purpose, Procedure Meaning and Interpretation - Drlogy Test

 

IGRA TB Test Preparation

Here is the basic preparation for the IGRA TB Test.

 

Before Test

  • No special dietary or medication restrictions are necessary.
  • Inform your healthcare provider about any medications or medical conditions.
  • Be prepared for a blood sample to be drawn.

 

During Test

  • A blood sample will be taken by a healthcare professional.

 

After Test

  • You can resume your normal activities and diet immediately.
  • Follow up with your healthcare provider for test results and interpretation.

 

IGRA TB Test Procedure

Here is the basic IGRA TB Test Procedure.

  • Schedule an appointment with a healthcare provider for an IGRA TB test.
  • No fasting or specific dietary restrictions are typically needed before the test.
  • Arrive at the healthcare facility or laboratory for your appointment.
  • A healthcare professional will draw a blood sample from a vein, typically in your arm.
  • Alternatively, if the QuantiFERON-TB Gold test is used, blood is collected directly into specialized tubes.
  • The blood sample is sent to a laboratory for analysis.
  • Test results are usually available within a few days, and you'll receive them from your healthcare provider.

 

IGRA TB Test Result

IGRA TB test results are typically reported as either positive or negative.

  • A positive result indicates exposure to tuberculosis infection.
  • A negative result suggests the absence of current infection, but it doesn't rule out past exposure or potential future infection.

 

IGRA TB Test Normal Result

Here is the normal result of the IGRA TB Test.

Test Name Normal Range
IGRA TB Test  Negative for no immune reaction to TB bacteria

 

IGRA TB Test Interpretation

Here is the Interpretation of the IGRA TB Test.

Test Result Interpretation
Positive Indicates that there is an immune reaction to TB bacteria, suggesting likely TB infection.
Negative Suggests that there is no immune reaction to TB bacteria, indicating that TB infection is unlikely.
Uninterpretable The test result is inconclusive, invalid, or borderline, and further evaluation is needed.

 

IGRA TB Test Positive Result

 

IGRA TB Test Negative Result 

 

Specimen Requirements For IGRA TB Test

Here are the specimen requirements for the IGRA TB Test.

Specimen

Serum

Volume

1 ml

Container

Red-top tube or gel-barrier tube

Collection

Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.

Storage

Refrigerate or freeze.

Sample Stability

Temperature

Period

Room temperature

7 day

Refrigerated

14 days

Frozen

60 days

Freeze/thaw cycles

Stable x1

Causes for Rejection

Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types

 

IGRA TB Test is Safe?

  • The IGRA TB test is generally considered safe and poses minimal risk to patients.
  • It does not involve the use of live tuberculosis bacteria, reducing the risk of infection.

 

When Do You Get IGRA TB Test Results? 

  • IGRA TB test results are typically available within 24 hrs after the blood sample is collected.
  • The exact timing may vary depending on the laboratory and healthcare facility conducting the test.

 

IGRA TB Test Limitation

Here is the basic limitation of IGRA TB Test.

  • The IGRA TB test may produce false-positive or false-negative results in certain situations.
  • It cannot differentiate between latent TB infection and active TB disease.
  • Test accuracy can be affected by the person's immune status and other factors.
  • IGRA testing may not be suitable for individuals with specific medical conditions or those on immunosuppressive treatments.
  • A positive result does not confirm active TB but indicates potential exposure or latent infection. Clinical evaluation is needed to make a diagnosis.

 

IGRA TB Test Risk Factors

Here are some of the risk factors of the IGRA TB Test.

  • The IGRA TB test carries minimal risk and is considered safer than the Tuberculin skin test.
  • It does not cause a tuberculosis infection or active disease.
  • There are no allergic reactions to test substances.
  • Very rarely, some individuals may experience mild irritation at the injection site.
  • The test is generally safe for pregnant women and those with weakened immune systems. However, discuss any specific health concerns with your healthcare provider.

 

Doctor Recommendations After IGRA TB Test Result

 Here are the Doctor's recommendations or consult a specialist after the IGRA TB Test.

IGRA TB Test Result Doctor to Visit Reason
High Pulmonologist Likely active tuberculosis infection
Normal No specific doctor Results within normal range
Low General Practitioner Potential past TB exposure or other issues

 

IGRA TB Test Price

Here are the estimated IGRA TB Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

1500-4500

New Delhi

2000-4500

Bangalore

1500-4500

Hyderabad

2000-4500

Kolkata

1500-4500

Pune

2000-4500

Lucknow

1500-4500

Noida

2000-4500

Surat

2000-4500

Gurugram

1500-4500

Patna

2000-4500

Chennai

1500-4500

Jaipur

2000-4500

Ahmedabad

1500-4500

*Prices are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall, IGRA TB Test is essential for detecting latent tuberculosis infection, aiding in early intervention and preventing the spread of active TB. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • IGRA TB Test - Wikipedia [1].
  • IGRA TB Test - NIH [2].
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IGRA TB Test FAQ

What is an IGRA TB test?

An IGRA (Interferon-Gamma Release Assay) TB test is a blood test used to detect tuberculosis (TB) infection in individuals. It is an important diagnostic tool in the fight against TB, as it provides a more specific and accurate result compared to the traditional Tuberculin Skin Test (TST).

How does the IGRA TB test work?

The IGRA TB test works by measuring the response of the immune system's T cells to TB-specific antigens. When a person is infected with the TB bacterium, their immune system produces interferon-gamma in response to these antigens. The IGRA test quantifies the amount of interferon-gamma released, helping to determine whether a person has been exposed to TB.

Who should get an IGRA TB test?

The IGRA TB test is typically recommended for individuals who are at an increased risk of TB exposure or infection. This includes healthcare workers, people with known TB contacts, and those from regions with a high TB prevalence. It is also used for immigration and healthcare worker screening.

Can I get an IGRA TB test at home?

While some tests can be conducted at home, the IGRA TB test typically requires a healthcare provider to collect the blood sample. Self-administered versions of the test are not widely available due to the need for precise handling and analysis of the blood sample.

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