IGF-1 (Insulin-like Growth Factor 1) Test For Growth Hormone Deficiency

IGF-1 (Insulin-like Growth Factor 1) Test For Growth Hormone Deficiency

The IGF-1 test checks a hormone related to growth. It helps find issues like slow growth or excess growth, often due to a pituitary problem. It's vital for kids' growth and can help adults with bone or muscle problems too.

 

IGF-1 Test

Here are the basic details of the IGF-1 Test.

Also Known As Insulin-like Growth Factor-1
Type Blood test
Purpose Diagnosing and monitoring growth hormone conditions
Sample Type Serum
Preparation No
Fasting 10-12 hours
Gender Unisex
Age Group All
Normal Value 64-240 ng/dL
Reporting Time 1-2 days
Cost 1900-4000 INR*

*IGF-1 Test Price range may vary as per location, lab type, and lab test procedure.

 

IGF-1 Test Means

The IGF-1 test, or Insulin-like Growth Factor-1 test, measures a hormone related to growth and development.

  • It's used to diagnose growth hormone conditions in children and adults.
  • IGF-1 levels can help identify issues like slow growth, excess growth, and pituitary problems.
  • This blood test often requires fasting for accurate results.
  • Results vary by age and gender, with normal values providing critical insights into overall health and growth.

 

IGF-1 Test Purpose

The purpose of the IGF-1 Test is to:

  • The IGF-1 test is essential for identifying growth hormone conditions, helping detect slow growth in children and bone/muscle issues in adults.
  • It assesses pituitary gland health, aiding in the diagnosis of hormonal imbalances.
  • IGF-1 levels track the effectiveness of growth hormone therapy.
  • IGF-1 assists in diagnosing conditions like acromegaly and gigantism, often caused by pituitary tumors.
  • In adults, IGF-1 is crucial for identifying low bone density, reduced muscle mass, and altered lipid levels.

IGF-1 Test- Price, Normal Range, Result, Purpose, Procedure Meaning and Interpretation - Drlogy Test

 

IGF-1 Test Preparation

Here is the basic preparation for the IGF-1 Test.

 

Before Test

  • Fasting for 10-12 hours may be required for accurate results.
  • Consult your healthcare provider if you're taking high doses of biotin.
  • You may need to stop it 72 hours before testing.

 

During Test

  • A blood sample is drawn from a vein in your arm.
  • The procedure is typically quick and relatively painless.

 

After Test

  • Resume your regular activities, as no special post-test care is usually needed.
  • Await the results, which are typically available within 1-2 days.

 

IGF-1 Test Procedure

Here is the basic IGF-1 Test Procedure.

  • Blood sample drawn from arm vein.
  • Needle insertion may cause minor discomfort.
  • Sample sent to a laboratory for analysis.
  • Results usually available within 1-2 days.
  • No specific post-test care required.

 

IGF-1 Test Result

Here is the basic reading of the IGF-1 Test results.

  • Normal levels vary by age and gender.
  • Low IGF-1 may indicate GH deficiency or insensitivity.
  • High IGF-1 often suggests increased GH production.
  • It is linked to conditions like acromegaly and gigantism.

 

IGF-1 Test Normal Range

Here is the normal range of the IGF-1 Test.

Age Group Normal Range (ng/dL)
Infants 25 - 548
Children 75 - 450
Adolescents 115 - 307
Adults 64 - 240

 

IGF-1 Test Interpretation

Here is the Interpretation of the IGF-1 Test.

Test Result (ng/dL) Interpretation
Below Normal Range May indicate GH deficiency or insensitivity.
Within Normal Range Considered within the expected range for age and gender.
Above Normal Range Suggests increased GH production.

The IGF-1 test measures a hormone related to growth and is used to diagnose and monitor growth hormone conditions, with results falling within specific reference ranges.

 

IGF-1 Test High Levels

Here are the potential causes of high IGF-1 Test levels:

Possible Causes Description
Pituitary Tumors Benign tumors increase GH, elevating IGF-1.
Acromegaly Rare GH excess condition raises IGF-1 levels.
Gigantism GH excess in children results in elevated IGF-1.
Insulin Resistance Some cases of insulin resistance affect IGF-1.
Rare Genetic Conditions Genetic factors may lead to high IGF-1 levels.

High IGF-1 levels, often caused by conditions like pituitary tumors or acromegaly, can be detected through this test, indicating growth hormone excess.

 

IGF-1 Test Low Levels

Here are the potential causes of low IGF-1 Test levels:

Possible Causes Description
GH Deficiency Insufficient growth hormone production leads to low IGF-1.
Pituitary Dysfunction Pituitary gland issues may result in decreased IGF-1 levels.
Malnutrition Chronic malnutrition can lead to decreased IGF-1 production.
Liver Disease Liver problems can affect IGF-1 synthesis and cause deficiency.
Genetic Factors Rare genetic conditions may contribute to low IGF-1 levels.

Low IGF-1 levels, often due to factors like growth hormone deficiency or malnutrition, may indicate underlying health issues.

 

Specimen Requirements For IGF-1 Test

Here are the specimen requirements for the IGF-1 Test.

Specimen

Serum, frozen

Volume

0.5 mL

Container

Red-top tube or gel-barrier tube

Collection

Serum must be separated from cells within 45 minutes of venipuncture. Send serum in a plastic transport tube

Storage

Freeze

Sample Stability

Temperature

Period

Room temperature

2 days

Refrigerated

2 days

Frozen

2 years

Causes for Rejection

Specimen not serum

 

IGF-1 Test is Safe?

  • Insulin-like Growth Factor-1 testing is generally safe.
  • It involves a simple blood draw, which is a common and low-risk procedure.
  • Adverse reactions are rare and typically limited to minor bruising or discomfort at the injection site.
  • It is considered safe for individuals of all ages when performed by a qualified healthcare professional.
  • Potential risks or discomfort are minimal compared to the valuable diagnostic information provided by the test.

 

When Do You Get IGF-1 Test Results? 

  • IGF-1 test results are typically available within 1-2 days.
  • The exact reporting time may vary depending on the laboratory and healthcare provider.
  • Rapid reporting enables prompt diagnosis and treatment decisions.
  • Patients can expect to receive their results relatively quickly.

 

IGF-1 Test Limitation

Here is the basic limitation of the IGF-1 Test.

  • IGF-1 levels can vary by age, gender, and individual factors.
  • The reference ranges may differ among laboratories.
  • Results may be influenced by medications or underlying health conditions.
  • It measures IGF-1 levels at a specific point in time, which may not capture daily fluctuations in growth hormone.
  • Additional tests are often needed for a comprehensive assessment of growth hormone-related disorders.

 

IGF-1 Test Risk Factors

Here are some of the risk factors of the IGF-1 Test.

  • Minimal risk associated with the IGF-1 test due to a routine blood draw.
  • Potential risks include bruising or discomfort at the needle insertion site.
  • Rare allergic reactions or fainting may occur in some individuals.
  • Risks are generally outweighed by the diagnostic benefits of the test.
  • Safe for most people when performed by a qualified healthcare professional.

 

Doctor Recommendations After IGF-1 Test Result

 Here are the Doctor's recommendations or consult a specialist after the IGF-1 Test.

IGF-1 Test Result Doctor to Visit Reason
High Endocrinologist Evaluate possible GH excess.
Normal Primary Care Physician Discuss overall health and well-being.
Low Endocrinologist Investigate GH deficiency or other issues.

 

IGF-1 Test Price

Here are the estimated IGF-1 Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

2000-3000

New Delhi

2500-4000

Bangalore

2000-3000

Hyderabad

1900-4000

Kolkata

2000-3000

Pune

2500-4000

Lucknow

2000-3000

Noida

2500-4000

Surat

2500-4000

Gurugram

2000-3000

Patna

2500-4000

Chennai

2000-3000

Jaipur

2500-4000

Ahmedabad

2000-3000

*IGF-1 Test Price are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall,The IGF-1 test measures a hormone related to growth, helping diagnose growth hormone disorders and assess overall health. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • Insulin-like growth factor 1 - Wikipedia [1].
  • Insulin-Like Growth Factor-1 (IGF-1) and Its Monitoring in ... - NIH [2].
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IGF-1 Test FAQ

What is an IGF-1 test?

An IGF-1 test measures Insulin-like Growth Factor 1, a hormone produced by the liver in response to growth hormone. It assesses growth hormone levels and potential growth-related issues.

What does it mean if IGF-1 level is high?

Elevated IGF-1 levels may indicate excess growth hormone, potentially linked to acromegaly or gigantism. It could also suggest conditions like tumors or excessive growth hormone production.

What is the function of IGF-1?

IGF-1 plays a crucial role in promoting growth during childhood and maintaining tissues and organs throughout life. It stimulates cell growth, division, and regeneration in various tissues.

Is IGF-1 good or bad for you?

In proper amounts, IGF-1 is essential for normal growth and development. However, excessively high levels can lead to health issues, including abnormal growth patterns and increased cancer risk.

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