Galectin-3 Test For Inflammation and Fibrosis

Galectin-3 Test For Inflammation and Fibrosis

The Galectin-3 Test is a blood test that measures the level of Galectin-3, a protein associated with inflammation and fibrosis. It helps assess the risk of heart failure and certain inflammatory diseases.

 

Galectin-3 Test

Here are the basic details of the Galectin-3 Test.

Test Name Galectin-3 Test
Also Known As Galectin-3 Blood Test
Type Blood Test
Purpose Assess Heart and Fibrosis Conditions
Sample Type Blood Sample
Preparation None
Fasting Not Required
Gender All
Age Group All
Normal Value 0 - 22.2 ng/mL
Reporting Time 3-4 Days
Cost 3000-4000 INR*

*Price range may vary as per location, lab type, and procedure of lab test.

 

Galectin-3 Test Means

The Galectin-3 test evaluates the level of Galectin-3, a protein associated with inflammation and fibrosis, in a person's blood.

  • Galectin-3 is involved in various disease processes, including heart disease and fibrotic disorders.
  • This test is used to assess the risk or severity of these conditions.
  • Results are reported as the concentration of Galectin-3, typically in nanograms per milliliter (ng/mL) or another appropriate unit.
  • Abnormal levels may indicate an increased risk or progression of certain diseases.
  • The test is valuable for early detection, risk assessment, and monitoring of associated health issues.

 

Galectin-3 Test Purpose

The purpose of the Galectin-3 Test is to:

  • Assess the risk and severity of heart disease and fibrotic disorders.
  • Measure Galectin-3 protein concentration in the blood.
  • Aid in early detection and risk assessment.
  • Monitor disease progression and treatment effectiveness.
  • Guide clinical decisions for cardiovascular and fibrotic conditions.
  • Improve patient outcomes and quality of care.

Galectin-3 Test- Price, Normal Range, Result, Purpose, Procedure Meaning and Interpretation - Drlogy Test

 

Galectin-3 Test Preparation

Here is the basic preparation for the Galectin-3 Test.

 

Before Test

  • No specific dietary or medication restrictions.
  • Provide a complete medical history and any relevant information.
  • Understand the test's purpose in assessing heart disease and fibrotic disorders.

 

During Test

  • No specific actions are required during the test.

 

After Test

  • Follow any post-test instructions given by the healthcare provider.
  • Discuss the results and their implications for heart disease and fibrosis management.
  • Be prepared for further evaluation and potential treatment as recommended.

 

Galectin-3 Test Procedure

Here is the basic Galectin-3 Test Procedure.

  • The Galectin-3 Test involves collecting a blood sample from the patient, typically from a vein in the arm.
  • The collected blood is processed to isolate the serum.
  • Laboratory techniques, such as ELISA, are used to measure the concentration of Galectin-3 protein in the serum.
  • Test results are reported in nanograms per milliliter (ng/mL) or another appropriate unit.
  • The procedure is essential for assessing the risk and severity of heart disease and fibrotic disorders.
  • Accurate results aid in early detection and informed clinical decisions for cardiovascular and fibrosis management.

 

Galectin-3 Test Result

Here is the basic reading of the Galectin-3 Test results.

  • Check the test report for the numerical value indicating the concentration of Galectin-3 protein.
  • Ensure the value falls within the reference range provided in the report.
  • If the result is within the reference range, it suggests a normal Galectin-3 level.
  • Abnormal results outside the range may indicate an increased risk or severity of heart disease or fibrotic disorders, requiring further evaluation and potential intervention

 

Galectin-3 Test Abnormal Result Report

Galectin 3 Test Abnormal Result Report Format High Leveles - Drlogy Test

Galectin-3 Test High Levels Result Report

Galectin-3 Test Abnormal Result Report PDF

 

Galectin-3 Test Normal Result Report

Galectin 3 Test Normal Result Report Format Low Levels - Drlogy Test

Galectin-3 Test Low Levels Result Report

Galectin-3 Test Normal Result Report PDF

 

Galectin-3 Test Normal Range

Here is the normal range of the Galectin-3 Test

Test Name Normal Range
Galectin-3 Test 0 - 22.2 ng/mL

 

Galectin-3 Test Interpretation

Here is the Interpretation of the Galectin-3 Test.

Galectin-3 Test Result Interpretation
0 - 22.2 ng/mL Within the normal range.
> 22.2 ng/mL Elevated levels, are a potential concern with a possible impact on heart and fibrosis conditions.

 

Galectin-3 Test High Levels

Here are the potential causes of High Levels of the Galectin-3 Test.

Potential Causes Description
Heart Failure Elevated levels may indicate heart failure, as Galectin-3 is associated with cardiac fibrosis and remodeling.
Inflammation and Infection Inflammatory conditions or infections can lead to increased Galectin-3 levels as part of the immune response.
Kidney Disease Kidney dysfunction can cause Galectin-3 to accumulate in the blood.
Cancer Some cancers, particularly certain types of solid tumors, may result in elevated Galectin-3 levels.
Liver Disease Liver damage and fibrosis can lead to increased Galectin-3 levels.
Autoimmune Diseases Conditions like rheumatoid arthritis and systemic lupus erythematosus can trigger higher Galectin-3 levels.
Diabetes Elevated levels may be associated with diabetes and its complications.
Pulmonary Disease Chronic obstructive pulmonary disease (COPD) and pulmonary fibrosis can result in increased Galectin-3.
Neurological Disorders Conditions such as Alzheimer's disease and multiple sclerosis may be linked to higher Galectin-3 levels.
Obesity Obesity is associated with chronic inflammation, which can elevate Galectin-3.
Medications Certain medications, like angiotensin-converting enzyme (ACE) inhibitors, can increase Galectin-3 levels.

 

Galectin-3 Test Low Levels

Here are the potential causes of low levels of the Galectin-3 Test.

Potential Causes Description
Normal Variation Low Galectin-3 levels in an otherwise healthy individual may simply represent normal variation.
Malnutrition Severe malnutrition or undernutrition can lead to decreased Galectin-3 levels.
Rare Genetic Conditions Some rare genetic conditions may result in low Galectin-3 levels.
Medications Certain medications, such as immunosuppressants, can decrease Galectin-3 levels.
Chronic Inflammatory Disorders In some cases of chronic inflammatory disorders, Galectin-3 levels may be reduced.
Severe Liver Disease In advanced liver disease, low Galectin-3 levels may occur.
Immune System Deficiency Conditions causing immune deficiency may lead to decreased Galectin-3 levels.

 

Specimen Requirements For Galectin-3 Test

Here are the specimen requirements for the Galectin-3 Test.

Specimen

Serum

Volume

1 ml

Container

Red-top tube or gel-barrier tube

Collection

If a red-top tube is used, transfer the separated serum to a plastic transport tube.

Storage

Room temperature

Sample Stability

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Visible hemolysis; improperly labeled specimens

 

 

Galectin-3 Test is Safe?

  • The Galectin-3 Test is safe, employing a common blood sampling method conducted by trained professionals.
  • Risks associated with the test are minimal, usually limited to mild discomfort or bruising at the blood draw site.
  • It is considered a safe diagnostic test for assessing the risk and severity of heart disease and fibrotic disorders.

 

When Do You Get Galectin-3 Test Results? 

  • Galectin-3 Test results are generally available within 3-4 days, depending on the laboratory's processing time.
  • Patients can expect to receive their test results from their healthcare provider once the analysis is completed.

 

Galectin-3 Test Limitation

Here is the basic limitation of the Galectin-3 Test.

  • Elevated Galectin-3 levels are not specific to a particular disease and may occur in various health conditions.
  • Results may not indicate the cause of elevated Galectin-3 levels.
  • Limited to measuring Galectin-3 concentration in blood and not other tissues.
  • Interpretation can be challenging due to the multifactorial nature of heart disease and fibrotic disorders.
  • Positive results require clinical context for proper assessment and management.

 

Galectin-3 Test Risk Factors

Here are some of the risk factors of the Galectin-3 Test.

  • Elevated Galectin-3 levels are not specific to a particular disease and may occur in various health conditions.
  • Results may not indicate the cause of elevated Galectin-3 levels.
  • Limited to measuring Galectin-3 concentration in blood and not other tissues.
  • Interpretation can be challenging due to the multifactorial nature of heart disease and fibrotic disorders.
  • Positive results require clinical context for proper assessment and management.

 

Doctor Recommendations After Galectin-3 Test Result

 Here are the Doctor's recommendations or consult a specialist after the Galectin-3 Test.

Galectin-3 Result Doctor to Visit Reason to See Doctor
High Cardiologist Heart health and potential issues.
Normal General Practitioner Discuss results for context.
Low Internist or Specialist Investigate underlying conditions.

 

Galectin-3 Test Price

Here are the estimated Galectin-3 Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

3000-4000

New Delhi

3500-4000

Bangalore

3000-4000

Hyderabad

3500-4000

Kolkata

3000-4000

Pune

3500-4000

Lucknow

3000-4000

Noida

3500-4000

Surat

3500-4000

Gurugram

3000-4000

Patna

3500-4000

Chennai

3000-4000

Jaipur

3500-4000

Ahmedabad

3000-4000

*Galectin-3 Test Prices are approximate and vary depending on a specific laboratory or healthcare facility.

 

 

Summary

Overall, Galectin-3 Test is significant for assessing the risk and severity of heart disease and fibrotic disorders, aiding in early detection and clinical decisions. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • Galectin-3 - Wikipedia [1].
  • Galectin-3: a novel blood test for the evaluation and management of patients with heart failure - NIH [2].

 

favorite_border 5012 Likes

Galectin-3 Test FAQ

What is the galectin-3 blood test?

The galectin-3 blood test measures the levels of galectin-3, a protein, in the blood. It's used to assess its presence in various health conditions.

What is galectin-3 a marker for?

Galectin-3 is a marker for inflammation and fibrosis. Elevated levels can indicate cardiac or kidney issues, among other conditions.

What does high galectin-3 mean?

High galectin-3 levels may suggest an increased risk of heart disease, kidney problems, or inflammation-related disorders. Further evaluation is needed for a precise diagnosis.

How do I reduce galectin-3?

Reducing galectin-3 levels isn't a straightforward process. Managing underlying conditions, such as heart disease or kidney problems, can indirectly help lower galectin-3.

Drlogy Testclose

Top Test

Profile Test

Medical Condition

Sample Test

Test Category

Drlogy®
The Power To Health

Copyright © 2024 Drlogy. All rights reserved.