Factor XII Test For Blood Clotting Disorders

Factor XII Test For Blood Clotting Disorders

The Factor XII Test evaluates the activity of factor XII in the blood, which plays a role in the blood clotting process, and helps diagnose certain clotting disorders.

 

Factor XII Test

Here are the basic details of the Factor XII Test.

Test Name Factor XII Test
Also Known As Hageman Factor Test
Type Coagulation
Purpose Assess Factor XII levels
Sample Type Blood plasma
Preparation Fasting may be required
Gender Any
Age Group All ages
Normal Value 70 - 120% 
Reporting Time Few Days
Cost 2000-4000 INR*

*Factor XII Test Price range may vary as per location, lab type, and lab test procedure.

 

Factor XII Test Means

The Factor XII test is a laboratory analysis used to determine the concentration and functionality of factor XII in the blood.

  • Factor XII is a component of the intrinsic coagulation pathway and plays a role in blood clotting.
  • Testing factor XII is valuable in assessing bleeding disorders and thrombosis risk.
  • Factor XII deficiency is generally asymptomatic, but its measurement is essential in specific clinical scenarios.
  • This test helps healthcare professionals evaluate the overall coagulation profile and guide appropriate treatment.
  • Factor XII testing is a component of the broader coagulation panel for comprehensive diagnosis.

 

Factor XII Test Purpose

The purpose of the Factor XII Test is to:

  • Assesses the concentration and functionality of factor XII in the blood.
  • Helps evaluate bleeding disorders and thrombosis risk.
  • Detects factor XII deficiency, even if generally asymptomatic.
  • Contributes to comprehensive coagulation profile assessment.
  • Guides appropriate treatment decisions for coagulation abnormalities.

Factor XII Test- Price, Normal Range, Result, Purpose, Procedure Meaning and Interpretation - Drlogy Test

 

Factor XII Test Preparation

Here is the basic preparation for the Factor XII Test.

 

Before Test

  • Your healthcare provider will assess the need for the Factor XII test and provide any necessary instructions or information.
  • Be prepared to share your medical history, particularly any history of bleeding or clotting disorders, to assist your healthcare provider in their decision-making.

 

During Test

  • Follow any instructions given by the healthcare team, such as remaining calm and cooperative during the blood sample collection.
  • If you experience any discomfort or have questions about the test, communicate with the healthcare providers involved.

 

After Test

  • After the Factor XII test is completed, you may inquire about the anticipated timeline for receiving test results and any follow-up steps.
  • Resume your normal activities, as directed by your healthcare provider, unless advised otherwise.
  • Remember that the interpretation of test results and any necessary actions will be carried out by your healthcare team.

 

Factor XII Test Procedure

Here is the basic Factor XII Test Procedure.

  • Collect a blood sample from the patient via venipuncture.
  • Anticoagulate the blood to prevent clot formation.
  • In the laboratory, perform a coagulation test to assess factor XII functionality.
  • Evaluate the clotting time in the presence of specific reagents.
  • Results are analyzed to detect factor XII deficiencies or abnormalities.
  • Abnormal factor XII results guide the diagnosis of coagulation disorders.

 

Factor XII Test Result

Here is the basic reading of the Factor XII Test results.

  • Factor XII test results are reported as a numerical value, often in percentage terms, reflecting the functionality or concentration of factor XII in the blood.
  • Elevated or reduced factor XII levels may be indicative of specific coagulation disorders, but factor XII deficiency is typically asymptomatic.
  • Normal factor XII results are generally expected in individuals without coagulation abnormalities.
  • Interpretation of factor XII results is performed in the context of the patient's clinical history and coagulation profile.

 

Factor XII Test Normal Result Report

Factor XII Test Normal Result Report Format - Drlogy Test

Factor XII Test Normal Report

Factor XII Test Normal Result Report PDF

 

Factor XII Test Abnormal Result Report

Factor XII Test Abnormal Result Report Format - Drlogy Test

Factor XII Test Abormal Report

Factor XII Test Abnormal Result Report PDF

 

Factor XII Test Normal Range

Here is the normal range of the Factor XII Test.

Factor XII Test Normal Range (%)
Factor XII  70 - 120

 

Factor XII Test Interpretation

Here is the Interpretation of the Factor XII Test.

Factor XII Level Interpretation
Below 70% May indicate a Factor XII deficiency, but clinical significance is often limited.
70 - 120% Indicates a typical level of Factor XII.
Above 120% Elevated Factor XII levels are not typically associated with specific clinical conditions.

 

Factor VII Activity High Levels

Here are the potential causes of high Factor XII Test levels:

Potential Causes Explanation
Generally Not Clinically Significant Elevated Factor XII levels are typically not associated with specific clinical conditions.

 

Factor VII Activity Low Levels

Here are the potential causes of low Factor XII Test levels:

Potential Causes Explanation
Factor XII Deficiency A rare genetic disorder resulting in low Factor XII levels.
Abnormalities in the Contact System Conditions affecting the contact system of coagulation.

 

Specimen Requirements For Factor XII Test

Here are the specimen requirements for the Factor XII Test.

Specimen

Blood Plasma 

Volume

1 mL

Container

Na Cit

Collection

Plasma Na Cit

Storage

Room temperature

Sample Stability

Temperature

Period

Frozen

14 days

Causes for Rejection

Gross hemolysis, Gross lipemia, and Gross icterus

 

Factor XII Test is Safe?

The Factor XII Test is generally safe and minimally invasive.

  • It involves a routine blood sample collection, which carries minimal risks typically associated with venipuncture, such as mild bruising or discomfort at the needle insertion site.
  • Factor XII deficiency, if present, is usually asymptomatic and does not pose additional risks during blood collection.

 

When Do You Get Factor XII Test Results? 

  • Factor XII Test results are generally available within a few days, subject to the laboratory's operational timeframe.
  • Patients are encouraged to reach out to their healthcare provider or the testing facility for specific information on when they will receive the test results.

 

Factor XII Test Limitation

Here is the basic limitation of the Factor XII Test.

  • Limited clinical significance, as deficiencies are typically not associated with bleeding disorders.
  • Not a routine test and not part of standard clotting factor panels.
  • Variability in reference ranges between laboratories.
  • Factor XII levels can be influenced by various non-pathological factors.
  • This may lead to unnecessary concern when low levels are detected without clinical significance.

 

Factor XII Test Risk Factors

Here are some of the risk factors of the Factor XII Test.

  • Factor XII deficiencies are generally not associated with a bleeding diathesis, so there are limited risk factors.
  • Factors XII levels can vary naturally and do not necessarily reflect bleeding risk.
  • Rare genetic mutations can lead to Factor XII deficiency, but it is not commonly assessed.
  • Interpretation is challenging due to the limited clinical significance of Factor XII levels.
  • Test results may not be useful in assessing bleeding risk in most clinical situations.

 

Doctor Recommendations After Factor XII Test Result

 Here are the Doctor's recommendations or consult a specialist after the Factor XII Test.

Factor XII Test Result Doctor to Visit Reason for Visit
High General Doctor Evaluate for clinical significance
Normal General Doctor Routine assessment
Low Hematologist Investigate clotting abnormalities

 

Factor XII Test Price

Here are the estimated Factor XII Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

2000-4000

New Delhi

2500-4000

Bangalore

2000-4000

Hyderabad

2500-4000

Kolkata

2000-4000

Pune

2500-4000

Lucknow

2000-4000

Noida

2500-4000

Surat

2500-4000

Gurugram

2000-4000

Patna

2500-4000

Chennai

2000-4000

Jaipur

2500-4000

Ahmedabad

2000-4000

*Factor XII Test Price are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall, Factor XII Test assessing bleeding risk or diagnosing bleeding disorders, making it of limited importance in routine medical practice. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • Factor XII Test - Wikipedia [1].
  • Factor XII Test - NIH [2].

 

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Factor XII Test FAQ

What is a Factor XII test?

A Factor XII test is a blood test that measures the activity of Factor XII, a clotting protein in the blood. Factor XII is one of the many factors involved in the blood clotting process. This test helps in diagnosing bleeding disorders and monitoring clotting function.

Why is Factor XII testing done?

Factor XII testing is performed to investigate unexplained bleeding or clotting disorders. It's often used when other common clotting factor tests are inconclusive. Additionally, it may be done before surgery or to assess an individual's risk of thrombosis or bleeding tendencies.

How is the Factor XII test performed?

A Factor XII test is a simple blood test. A healthcare provider will draw a blood sample from a vein in your arm. The blood is then sent to a lab for analysis. No special preparation is usually required before the test.

Is Factor XII testing painful?

Factor XII testing involves a quick needle prick to draw a blood sample, which may cause mild discomfort. However, the pain is usually brief and well-tolerated by most individuals. The benefits of the test in diagnosing clotting disorders outweigh the temporary discomfort.

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