Factor XI Deficiency Test To Diagnose Bleeding Disorders

Factor XI Deficiency Test To Diagnose Bleeding Disorders

The Factor XI Deficiency test evaluates a clotting protein's levels. It's essential to diagnose bleeding disorders and guide treatment.

 

Factor XI Deficiency Test

Here are the basic details of the Factor XI Deficiency Test.

Test Name Factor XI Deficiency
Also Known As Hemophilia C Test
Type Blood Coagulation Test
Purpose Detect Factor XI Deficiency
Sample Type Blood
Preparation None
Fasting Not Required
Gender All
Age Group All
Normal Value 70-120%
Reporting Time Within 24 hrs
Cost 2400-3100 INR*

*Factor XI Deficiency Test Price range may vary as per location, lab type, and lab test procedure.

 

Factor XI Deficiency Test Means

Factor XI is a clotting protein in the blood.

  • The Factor XI deficiency test measures the level of Factor XI in the blood.
  • Low Factor XI levels can lead to a bleeding disorder.
  • This test is used to diagnose and monitor Factor XI deficiency.
  • It aids in assessing a person's risk of excessive bleeding.
  • It helps guide treatment decisions for individuals with Factor XI deficiency.

 

Factor XI Deficiency Test Purpose

The purpose of the Factor XI Deficiency Test is to:

  • Detect low Factor XI levels.
  • Diagnose and monitor Factor XI deficiency.
  • Assess bleeding disorder risk.
  • Guide treatment decisions.
  • Ensure effective medical management.

Factor XI Deficiency Test Price, Normal Range, Result, Purpose, Procedure Meaning and Interpretation - Drlogy Test

 

Factor XI Deficiency Test Preparation

Here is the basic preparation for the Factor XI Deficiency Test.

 

Before Test

  • Inform your healthcare provider about any medications, including blood-thinning drugs, that you are taking, as they can affect test results.
  • You may not need to fast for this test, but follow any specific instructions provided by your healthcare provider.
  • Be sure to mention any personal or family history of bleeding disorders.

 

During Test

  • A blood sample will be collected from a vein in your arm using a needle.
  • You may experience a brief needle prick or mild discomfort during the blood draw.
  • Stay still and follow the instructions of the healthcare professional during the procedure.

 

After Test

  • Apply gentle pressure to the puncture site with a cotton ball or bandage to stop any bleeding.
  • You can typically resume your usual activities right after the test.
  • Await your healthcare provider's discussion of the results and any recommendations for treatment or follow-up based on the Factor XI levels.

 

Factor XI Deficiency Test Procedure

Here is the basic Factor XI Deficiency Test Procedure.

  • Obtain a blood sample from a vein in the patient's arm.
  • Analyze the sample to measure Factor XI levels.
  • Results are usually available on the same day.
  • Review the results with the healthcare provider.
  • Adjust treatment or management according to Factor XI levels.
  • Consider ongoing monitoring for patients with Factor XI deficiency.

 

Factor XI Deficiency Test Result

Here is the basic reading of the Factor XI Deficiency Test results.

  • Factor XI Activity Level: The result is typically expressed as a percentage, with the normal range around 70-120%.
  • Low Activity (<70%): Indicates Factor XI deficiency, which can lead to bleeding issues, especially after trauma or surgery.
  • High Activity (>120%): Uncommon but may indicate an increased risk of blood clotting (thrombosis).
  • Clinical Evaluation Required: It's crucial to consider the patient's clinical symptoms, medical history, and other factors for an accurate diagnosis and appropriate treatment recommendations.

 

Factor XI Deficiency Test Normal Result Report

Factor XI Test Normal Result Report Format - Drlogy Test

Factor XI Deficiency Test Normal Report

Factor XI Deficiency Test Normal Result Report PDF

 

Factor XI Deficiency Test Abnormal Result Report

Factor XI Test Abnormal Result Report Format - Drlogy Test

Factor XI Deficiency Test Abnormal Report

Factor XI Deficiency Test Abnormal Result Report PDF

 

Factor XI Deficiency Test Normal Range

Here is the normal range of the Factor XI Deficiency Test.

Factor XI Activity Level Normal Range
Factor XI 70 - 120%

 

Factor XI Deficiency Test Interpretation

Here is the Interpretation of the Factor XI Deficiency Test.

Factor XI Activity Test Interpretation
<20 % Severe Factor XI deficiency
20 - 70 % Mild Factor XI deficiency
>70 % Normal Factor XI activity

 

Factor XI Deficiency Test High Levels

Here are the potential causes of high Factor XI Deficiency Test levels:

Potential Causes Description
Liver Disease Liver dysfunction can lead to elevated FXI levels.
Blood Disorders Certain blood disorders can increase FXI activity.
Pregnancy FXI levels can be elevated during pregnancy.
Medications Some medications can increase FXI levels.

 

Factor XI Deficiency Test Low Levels

Here are the potential causes of low Factor XI Deficiency Test levels:

Potential Causes Description
Factor XI Deficiency Low levels can indicate a congenital FXI deficiency.
Liver Disease Liver dysfunction can result in decreased FXI.
Medications Certain drugs can reduce FXI levels.
Autoimmune Disorders Some autoimmune conditions can lower FXI activity.

 

Specimen Requirements For Factor XI Deficiency Test

Here are the specimen requirements for the Factor XI Deficiency Test.

Specimen

Serum

Volume

0.8 mL

Container

Red-top tube or gel-barrier tube

Collection

If a red-top tube is used, transfer separated serum to a plastic transport tube.

Storage

Room temperature

Sample Stability

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x6

Causes for Rejection

Sample type other than serum received.

 

Factor XI Deficiency Test is Safe?

Typically safe, involving a blood sample.

  • Minimal risk of bleeding or infection.
  • Generally safe for most individuals, but consult with a healthcare provider for specific concerns.

 

When Do You Get Factor XI Deficiency Test Results? 

  • Usually available within 24hrs after the test is conducted.
  • The specific turnaround time can vary depending on the laboratory and healthcare provider.

 

Factor XI Deficiency Test Limitation

Here is the basic limitation of the Factor XI Deficiency Test.

  • Results may be influenced by medications.
  • Does not detect all potential bleeding disorders.
  • May not provide a complete assessment of bleeding risk.
  • Genetic factors can impact test interpretation.
  • Additional tests may be needed for a comprehensive evaluation.

 

Factor XI Deficiency Test Risk Factors

Here are some of the risk factors of the Factor XI Deficiency Test.

  • Family history of Factor XI deficiency.
  • Medications affecting clotting factors.
  • History of excessive bleeding or bruising.
  • Certain ethnic backgrounds (Ashkenazi Jewish descent).
  • Pregnancy may impact test results.

 

Doctor Recommendations After Factor XI Deficiency Test Result

 Here are the Doctor's recommendations or consult a specialist after the Factor XI Deficiency Test.

Factor XI Activity Doctor to Visit Reason to Go
High Hematologist Investigate clotting disorders
Normal Primary Care Routine health assessment
Low Hematologist Assess bleeding disorders

 

Factor XI Deficiency Test Price

Here are the estimated Factor XI Deficiency Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

2000-4000

New Delhi

2500-4000

Bangalore

2000-4000

Hyderabad

2500-4000

Kolkata

2000-4000

Pune

2500-4000

Lucknow

2000-4000

Noida

2500-4000

Surat

2500-4000

Gurugram

2000-4000

Patna

2500-4000

Chennai

2000-4000

Jaipur

2500-4000

Ahmedabad

2000-4000

*Factor XI Deficiency Test Price are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall, Factor XI Deficiency Test is crucial for diagnosing a rare clotting disorder and managing associated risks. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • Factor XI - Wikipedia [1].
  • Factor XI Deficiency - NIH [2].

 

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Factor XI Deficiency Test FAQ

What is Factor XI Deficiency?

Factor XI Deficiency, also known as Hemophilia C, is a rare bleeding disorder caused by insufficient levels of Factor XI, a blood clotting protein. It leads to prolonged bleeding after injuries or surgeries.

How is Factor XI Deficiency diagnosed?

A blood test is used to measure Factor XI levels. A low Factor XI level confirms the condition. Genetic testing can also identify the specific gene mutations causing the deficiency.

Is Factor XI Deficiency inherited?

Yes, it's usually inherited in an autosomal recessive manner, meaning both parents must carry the gene mutation for a child to be affected.

How is Factor XI Deficiency treated?

Treatment may involve recombinant Factor XI infusions or plasma-derived Factor XI concentrate to control bleeding episodes. Desmopressin (DDAVP) can be used for some cases.

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