Factor II Mutation Test For Blood Clotting Disorders

Factor II Mutation Test For Blood Clotting Disorders

The Factor II Mutation Test measures a clotting protein's activity. It's vital in diagnosing and managing blood clotting disorders.

 

Factor II Mutation Test

Here are the basic details of the Factor II Mutation Test.

Test Name Factor II Mutation Test
Also Known As Prothrombin Activity Test
Type Blood Coagulation Test
Purpose Measure Prothrombin Activity
Sample Type Blood
Preparation None
Fasting Not Required
Gender All
Age Group All
Normal Value 70-120%
Reporting Time Within Week
Cost 4000-5000 INR*

*Factor II Mutation Test Price range may vary as per location, lab type, and lab test procedure.

 

Factor II Mutation Test Means

Factor II, also known as prothrombin, is a blood clotting protein.

  • The Factor II Mutation Test assesses the activity of Factor II in the blood.
  • Abnormal Factor II activity can lead to bleeding or clotting disorders.
  • This test is essential for diagnosing and monitoring conditions related to Factor II.
  • It aids in determining the appropriate treatment and managing clotting disorders.
  • Factor II testing is valuable in guiding therapy decisions, especially in anticoagulant management.

 

Factor II Mutation Test Purpose

The purpose of the Factor II Mutation Test is to:

  • Measure Factor II (prothrombin) activity.
  • Diagnose clotting and bleeding disorders.
  • Determine treatment approaches.
  • Manage anticoagulant therapy.
  • Aid in clot-related condition care.

Factor II Mutation Test Price, Normal Range, Result, Purpose, Procedure Meaning and Interpretation - Drlogy Test

 

Factor II Mutation Test Preparation

Here is the basic preparation for the Factor II Mutation Test.

 

Before Test

  • Inform your healthcare provider about any medications you are taking, especially anticoagulants or blood-thinning drugs, as they can affect test results.
  • Typically, fasting is not required for this test, but follow any specific instructions provided by your healthcare provider.
  • Share any personal or family history of blood clots or clotting disorders with your healthcare provider.

 

During Test

  • A blood sample will be collected from a vein in your arm using a needle.
  • You may experience a brief needle prick or mild discomfort during the blood draw.
  • Cooperate with the healthcare professional performing the test and remain still during the procedure.

 

After Test

  • Apply gentle pressure to the puncture site with a cotton ball or bandage to stop any bleeding.
  • You can typically resume your regular activities right after the test.
  • Wait for your healthcare provider to discuss the results and any recommendations for treatment or follow-up based on the Factor II functional activity levels.

 

Factor II Mutation Test Procedure

Here is the basic Factor II Mutation Test Procedure.

  • Obtain a blood sample from a vein in the patient's arm.
  • Assess the sample to measure Factor II functional activity.
  • Results are typically available on the same day.
  • Discuss the results with the healthcare provider.
  • Adjust treatment or management as necessary based on Factor II function.
  • Regular monitoring may be recommended for patients with Factor II-related conditions.

 

Factor II Mutation Test Result

Here is the basic reading of the Factor II Mutation Test results.

  • Factor II Mutation: The result indicates whether a mutation in the Factor II (prothrombin) gene is present or not.
  • Positive Result (Mutation Detected): Suggests an increased risk of abnormal blood clot formation, which can lead to thrombophilia.
  • Negative Result (Mutation Not Detected): Indicates the absence of the Factor II mutation, reducing the risk of this specific clotting disorder.
  • Clinical Evaluation Required: A healthcare provider should interpret the test result in the context of the patient's medical history and other risk factors to assess the overall risk of clotting disorders and determine appropriate management.

 

Factor II Mutation Test Normal Result Report

Factor II Test Normal Result Report Format - Drlogy Test

Factor II Mutation Test Normal Report

Factor II Mutation Test Normal Result Report PDF

 

Factor II Mutation Test Abnormal Result Report

Factor II Test Abnormal Result Report Format - Drlogy Test

Factor II Mutation Test Abormal Report

Factor II Mutation Test Abnormal Result Report PDF

 

Factor II Mutation Test Normal Range

Here is the normal range of the Factor II Mutation Test.

Factor II Mutation Test Normal Range
Factor II Activity 70-120%

 

Factor II Mutation Test Interpretation

Here is the Interpretation of the Factor II Mutation Test.

Factor II Mutation Test Result
Prothrombin Mutation Detected
Prothrombin Mutation Not Detected

 

Factor II Mutation Test Detected Results

Here are the potential causes of detected Factor II Mutation Test results:

Potential Causes Description
Prothrombin G20210A Mutation Detection of the specific genetic mutation.
Increased Clotting Risk Elevated risk of abnormal blood clotting.
Genetic Inheritance Inherited mutation from one or both parents.
Thrombotic Events Personal or family history of blood clots.

 

Factor II Mutation Test Not Detected Results

Here are the potential causes of not detected Factor II Mutation Test results:

Potential Causes Description
Absence of Mutation The Prothrombin G20210A mutation is not present.
Reduced Clotting Risk Lower risk of abnormal blood clotting related to this mutation.
Negative Family History No family history of the mutation.
No Thrombotic Events No personal or family history of blood clots related to this mutation.

 

Specimen Requirements For Factor II Mutation Test

Here are the specimen requirements for the Factor II Mutation Test.

Specimen

Serum

Volume

0.8 mL

Container

Red-top tube or gel-barrier tube

Collection

If a red-top tube is used, transfer separated serum to a plastic transport tube.

Storage

Room temperature

Sample Stability

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x6

Causes for Rejection

Sample type other than serum received.

 

Factor II Mutation Test is Safe?

Generally safe, involving a blood sample.

  • Minimal risk of bleeding or infection.
  • Safe for most individuals, but consult with a healthcare provider for specific concerns.

 

When Do You Get Factor II Mutation Test Results? 

  • Usually available within a few days to a week after the test is performed.
  • The specific turnaround time can vary depending on the laboratory and healthcare provider.

 

Factor II Mutation Test Limitation

Here is the basic limitation of the Factor II Mutation Test.

  • Medications can affect test results.
  • Limited in identifying all clotting disorders.
  • May not provide a complete assessment of clotting risk.
  • Genetic factors can influence test interpretation.
  • Other tests may be necessary for a comprehensive evaluation.

 

Factor II Mutation Test Risk Factors

Here are some of the risk factors of the Factor II Mutation Test.

  • Family history of clotting disorders.
  • Medications affecting clotting factors.
  • Recent surgeries or trauma.
  • Liver disease.
  • Personal history of blood clots.

 

Doctor Recommendations After Factor II Mutation Test Result

 Here are the Doctor's recommendations or consult a specialist after the Factor II Mutation Test.

Factor II Mutation Test Result Doctor to Visit Reason
Not Detected No need N/A
Detected Hematologist Consultation & Management

 

Factor II Mutation Test Price

Here are the estimated Factor II Mutation Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

2000-4000

New Delhi

2500-4000

Bangalore

2000-4000

Hyderabad

2500-4000

Kolkata

2000-4000

Pune

2500-4000

Lucknow

2000-4000

Noida

2500-4000

Surat

2500-4000

Gurugram

2000-4000

Patna

2500-4000

Chennai

2000-4000

Jaipur

2500-4000

Ahmedabad

2000-4000

*Factor II Mutation Test Price are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall, Factor II Mutation Test helps diagnose clotting disorders and inform treatment strategies. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • Factor II (prothrombin) assay - UCSF Health [1].
  • Factor II - Health Encyclopedia - URMC - University of Rochester [2].

 

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Factor II Mutation Test FAQ

What is a Factor II Mutation Test?

A Factor II Mutation Test is a medical diagnostic test that assesses the presence of mutations in the Factor II gene, also known as the Prothrombin gene. These mutations can increase the risk of abnormal blood clot formation, potentially leading to conditions like deep vein thrombosis and pulmonary embolism.

How is the Factor II Mutation Test performed?

The Factor II Mutation Test is typically done through a blood sample. A healthcare professional will draw a blood sample, which is then sent to a laboratory for analysis. The lab checks for specific mutations in the Factor II gene. Results are usually available within a few days to a week.

Can the Factor II Mutation Test be done at home?

No, the Factor II Mutation Test must be conducted in a clinical setting or laboratory by a trained healthcare professional. Home testing kits are not typically available for this specific genetic test, as it requires precise sample handling and accurate analysis. It's important to consult your healthcare provider for proper testing.

What's the cost of a Factor II Mutation Test?

The cost of the test can vary depending on factors like your location, healthcare provider, and insurance coverage. Some insurance plans may partially or fully cover the cost of genetic testing if medically necessary. It's advisable to check with your insurance provider and the testing facility to determine your specific cost or coverage details.

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