Cystatin C Test For Kidney Function and Diseases

Cystatin C Test For Kidney Function and Diseases

The Cystatin C test is a blood test that measures a protein called cystatin C, providing an accurate and sensitive way to assess kidney function. It is especially useful in estimating the glomerular filtration rate (GFR) and can help diagnose and monitor kidney diseases.

 

Cystatin C Test

Here are the basic details of the Cystatin C Test.

Also Known As Cystatin-C eGFR Test
Type Blood Test
Purpose Assess kidney function and estimate GFR
Sample Type Serum
Preparation No special preparation needed
Fasting Fasting is not typically required
Gender All
Age Group All
Normal Value 0.62 - 1.15 mg/L
Reporting Time 1-2 days
Cost 1000-2000 INR*

*Price range may vary as per location, lab type, and procedure of lab test.

 

Cystatin C Test Means

Cystatin C test estimates glomerular filtration rate (GFR).

  • Cystatin C is a protein in the blood.
  • Cystatin C levels can indicate kidney function.
  • It is often used to assess and monitor kidney health.
  • Cystatin C can be a more reliable marker than creatinine.

 

Cystatin C Test Purpose

The purpose of the Cystatin C Test is to:

  • Assess kidney function.
  • Estimate glomerular filtration rate (GFR).
  • Monitor and diagnose kidney diseases.
  • Provide a more reliable marker than creatinine.
  • Offer valuable insights into overall kidney health.

Cystatin C Test: Price, Normal Range, Result, Purpose, Procedure Meaning and Interpretation - Drlogy Test

 

Cystatin C Test Preparation

Here is the basic preparation for the Cystatin C Test.

 

Before Test

  • No fasting or dietary restrictions are typically required.
  • Inform your healthcare provider about any medications or supplements you are taking.
  • Wear clothing with sleeves that can be easily rolled up.

 

During Test

  • A blood sample will be drawn from a vein, usually from the arm.
  • You may experience a brief, mild discomfort during the blood draw.

 

After Test

  • You can resume normal activities immediately.
  • You may experience slight bruising or soreness at the site of the blood draw, which should resolve on its own.
  • Follow any additional instructions or recommendations from your healthcare provider regarding the test results and any necessary follow-up.

 

Cystatin C Test Procedure

Here is the basic Cystatin C Test Procedure.

  • Schedule the test with your healthcare provider.
  • Arrive at the lab or healthcare facility for the test.
  • You may not need to fast or make special preparations.
  • A healthcare professional will draw a blood sample.
  • They will clean the injection site, often in your arm.
  • A needle will be inserted to collect a small blood sample.
  • You may feel mild discomfort during the blood draw.
  • The blood sample is then sent to a laboratory for analysis.
  • Results are typically available within a few days.
  • Your healthcare provider will discuss the results with you.
  • Follow any further recommendations or treatment if needed.

 

Cystatin C Test Result

Cystatin C test measures kidney function based on blood levels.

  • Higher values may indicate decreased kidney function.
  • Lower values typically indicate healthier kidney function.
  • Results are compared to a reference range for interpretation.

Consult a healthcare provider for a comprehensive analysis and guidance.

 

Cystatin C Test Normal Range

Here is the normal range of the Cystatin C Test

Category Normal Range (mg/L)
Adults 0.62 - 1.15
Children 0.53 - 1.07

 

Cystatin C Test Interpretation

Here is the Interpretation of the Cystatin C Test.

Cystatin C Level (mg/L) Interpretation
Less than 0.62 Low levels may indicate very efficient kidney function.
0.62 - 1.15 Typical reference range for adults; healthy kidney function.
Greater than 1.15 Elevated levels may suggest impaired kidney function.

Please note that reference ranges can vary slightly between laboratories, and interpretation should always be done in consultation with a healthcare provider.

 

Cystatin C Test High Levels

Here are the Potential Causes of High Cystatin C Levels.

High Cystatin C Levels Potential Causes
Kidney Dysfunction Impaired kidney function, renal disease.
Inflammation Inflammatory conditions or infections.
Thyroid Dysfunction Hypothyroidism or thyroid disorders.
High Blood Pressure Hypertension may impact kidney function.
Aging Normal age-related kidney changes.

Elevated Cystatin C levels can indicate various underlying health conditions and should be evaluated by a healthcare provider.

 

Cystatin C Test Low Levels

Potential Causes of Low Cystatin C Test Levels.

Low Cystatin C Test Levels Potential Causes
Reduced Muscle Mass Lower levels in individuals with muscle atrophy.
Malnutrition Inadequate protein intake or malnutrition.
Cirrhosis Liver disease can affect Cystatin C levels.
Thyroid Dysfunction Hyperthyroidism may reduce Cystatin C levels.
Inflammatory Conditions Conditions such as rheumatoid arthritis.

Low Cystatin C levels can result from various factors, including health conditions, nutritional status, and muscle mass, and should be assessed by a healthcare provider.

 

Specimen Requirements For Cystatin C Test

Here are the specimen requirements for the Cystatin C Test.

Specimen

Serum

Volume

0.5 ml

Container

Red-top tube, gel-barrier tube, or green-top (heparin) tube

Collection

Separate serum or plasma from red blood cells

Storage

Room temperature

Sample Stability

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

  • Specimen other than serum or heparinized plasma
  • Grossly hemolyzed (>1,000 mg/dL Hgb) samples
  • Excessive turbidity and clots in samples

 

Cystatin C Test is Safe?

Cystatin C test is generally safe and well-tolerated.

  • It involves a routine blood draw, which is a common procedure.
  • Risks are minimal and typically limited to mild discomfort or bruising at the injection site.

 

When Do You Get Cystatin C Test Results? 

  • Cystatin C test results are typically available within a few days.
  • Your healthcare provider will discuss the results with you during a follow-up appointment.

 

Cystatin C Test Limitation

Here is the basic limitation of the Cystatin C Test.

  • Cystatin C levels can be influenced by factors other than kidney function.
  • Results may be affected by certain medications or medical conditions.
  • Not suitable for assessing acute changes in kidney function.
  • Reference ranges may vary between laboratories.
  • Interpretation should consider the patient's overall clinical context.

 

Cystatin C Test Risk Factors

Here are some of the risk factors of the Cystatin C Test.

  • Certain medications can influence Cystatin C levels.
  • Chronic inflammation or infections may affect results.
  • Pre-existing kidney conditions can alter Cystatin C values.
  • Age and gender can impact reference ranges.

 

Doctor Recommendations After Cystatin C Test Result

 Here are the Doctor's recommendations or consult a specialist after the Cystatin C Test.

Cystatin C Result Doctor to Consult Reason to Visit Doctor
High Nephrologist Kidney function evaluation
Normal Primary Care Physician Routine checkup
Low Primary Care Physician Further evaluation

 

Cystatin C Test Price

Here are the estimated Cystatin C Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

1000-2000

New Delhi

1500-2000

Bangalore

1000-2000

Hyderabad

1500-2000

Kolkata

1000-2000

Pune

1500-2000

Lucknow

1000-2000

Noida

1500-2000

Surat

1500-2000

Gurugram

1000-2000

Patna

1500-2000

Chennai

1000-2000

Jaipur

1500-2000

Ahmedabad

1000-2000

*Prices are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall, Cystatin C Test provides a reliable assessment of kidney function and offers valuable insights into renal health. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • Cystatin C - Wikipedia [1].
  • Cystatin C - Kidney Org [2].
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Cystatin C Test FAQ

What is a Cystatin C Test?

The Cystatin C Test is a blood test that measures the levels of cystatin C, a protein produced by all cells in the body. It is primarily used as a marker of kidney function, particularly the glomerular filtration rate (GFR). Unlike traditional markers like creatinine, cystatin C is less influenced by factors like age, muscle mass, and diet, making it a valuable tool in assessing kidney health.

Why is the Cystatin C Test used?

The Cystatin C Test is used to evaluate kidney function, diagnose kidney diseases, and monitor the progression of chronic kidney disease (CKD). It can also help identify early kidney damage, assess the risk of cardiovascular disease, and guide medication dosages in certain cases. It offers a more accurate and sensitive measure of GFR than creatinine-based tests, especially in elderly patients or those with muscle-related conditions.

How is the Cystatin C Test performed?

The test involves a simple blood draw, usually from a vein in your arm. The blood sample is then sent to a laboratory for analysis. There's no need for fasting or special preparations before the test, making it convenient for patients. Results are typically available within a few days.

Can I receive the Cystatin C Test results online?

Many healthcare providers offer online access to test results through patient portals. You can discuss with your provider about online access or ask for a printed copy of your Cystatin C Test results during your follow-up appointment. It's essential to review the results with your healthcare provider to gain a full understanding of their implications.

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