Celiac Disease Antibody Test To Search Gluten Antibodies

Celiac Disease Antibody Test To Search Gluten Antibodies

The Celiac Disease Antibody Test is a blood test used to check for gluten sensitivity and celiac disease. It helps diagnose and monitor these conditions by measuring specific antibodies in the blood.

 

If you have symptoms like abdominal pain or digestive issues, this test can provide important information about your health. It's a valuable tool in understanding how your body reacts to gluten.

 

Celiac Disease Antibody Test

Here are the basic details of the Celiac Disease Antibody Test.

Also Known As Anti-tissue Transglutaminase Antibody, tTG
Type Blood test
Purpose To diagnose and monitor celiac disease
Sample Type Whole blood or buccal swabs and serum
Preparation No
Fasting Not required
Gender Unisex
Age Group All
Normal Value Negative
Reporting Time A few days
Cost 2500-5500 INR*

*Price range may vary as per location, lab type, and procedure of lab test.

 

Celiac Disease Antibody Test Means

Celiac Disease Antibody Test is a blood test to diagnose and monitor gluten-related conditions.

  • It measures specific antibodies in the blood to assess immune responses.
  • Used for diagnosing celiac disease, it helps identify gluten sensitivity.
  • A non-invasive method to evaluate intestinal health and gluten intolerance.
  • Vital tool in understanding how the body reacts to gluten, aiding in health management.

 

Celiac Disease Antibody Test Purpose

The purpose of the Celiac Disease Antibody Test is to:

  • Celiac Disease Antibody Test diagnoses gluten sensitivity.
  • It identifies celiac disease by detecting specific antibodies.
  • Aims to monitor the condition and treatment effectiveness.
  • Helps evaluate gluten-related symptoms like anemia and pain.
  • Supports early detection in at-risk individuals with close relatives.

Celiac Disease Antibody Test- Price, Normal Range, Result, Purpose, Procedure Meaning and Interpretation - Drlogy Test

 

Celiac Disease Antibody Test Preparation

Here is the basic preparation for the Celiac Disease Antibody Test.

 

Before Test

  • No specific dietary changes required.
  • Continue eating foods with gluten for several weeks if for diagnostic purposes.

 

During Test

  • A blood sample is drawn from a vein in your arm.
  • Quick and minimally invasive procedure.

 

After Test

  • Apply gentle pressure to the site to stop bleeding.
  • Resume normal activities immediately.

 

Celiac Disease Antibody Test Procedure

Here is the basic Celiac Disease Antibody Test Procedure.

  • Blood sample drawn from arm vein.
  • May use a band to tie upper arm.
  • Clean the insertion area.
  • Slight sting during needle insertion.
  • Quick, usually under 3 minutes.
  • Apply bandage after needle withdrawal.

 

Celiac Disease Antibody Test Result

  • Positive results indicate potential celiac disease.
  • Negative results suggest celiac disease is unlikely.
  • Further tests or biopsy may follow for confirmation.

 

Celiac Disease Antibody Test Normal Result

Here is the normal range of the Celiac Disease Antibody Test.

Antibody Tested Normal Result
tTG, IgA Negative
Total IgA Negative
tTG, IgG Negative
DGP, IgA Negative
DGP, IgG Negative

 

Celiac Disease Antibody Test Interpretation

Here is the Interpretation of the Celiac Disease Antibody Test.

tTG, IgA Total IgA tTG, IgG DGP, IgA DGP, IgG Diagnosis
Positive Normal Not performed Not performed Not performed Presumptive celiac disease
Negative Normal Negative Negative Negative Symptoms not likely due to celiac disease
Negative Low Positive Negative Positive Possible celiac disease (IgA deficiency)
Negative Normal Negative Positive Positive Possible celiac disease (children under 3)

Celiac Disease Antibody Test results vary, aiding in the diagnosis and evaluation of celiac disease and gluten sensitivity.

 

Celiac Disease Antibody Test Positive Result

Here are the potential causes of Celiac Disease Antibody Test Positive Results.

Possible Causes Description
Celiac Disease (Confirmed Diagnosis) Presence of celiac disease antibodies.
Gluten Sensitivity May indicate sensitivity to gluten.
Autoimmune Disorders Elevated antibodies due to other autoimmune conditions.
Non-Celiac Autoimmune Enteropathy (NCAE) Autoimmune intestinal disorders unrelated to celiac disease.

A positive result can be due to various factors, and further evaluation is often necessary to determine the exact cause.

 

Celiac Disease Antibody Test Negative Result

Here are the potential causes of Celiac Disease Antibody Test negative Results.

Possible Causes Description
Absence of Celiac Disease Test result does not show celiac disease antibodies.
Incomplete Gluten Exposure Negative result when gluten was not consumed before testing.
IgA Deficiency Low IgA levels may lead to false negatives in IgA-based tests.
Early Stages of Celiac Negative result in the early stages of celiac disease.
Other Health Conditions Negative results due to unrelated health conditions.

A negative result can be due to various factors, including early disease stages or insufficient gluten exposure before testing.

 

Specimen Requirements For Celiac Disease Antibody Test

Here are the specimen requirements for the Celiac Disease Antibody Test.

Specimen

Whole blood or buccal swabs and serum

Volume

7 mL of blood or four buccal swabs and 3 mL serum

Container

Lavender-top (EDTA) tube or four buccal swabs in a sealed envelope and gel-barrier tube.

Collection

Specimen should be collected to perform reflex assays if criteria is met.

Storage

Room temperature

Sample Stability

Temperature

Period

Room temperature

EDTA blood and serum: 14 days; Buccal swab: 1 year

Refrigerated

EDTA blood: 1 month; Serum: 14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Incorrect sample type; lack of proper patient identification on the tube; Serum: hemolysis, lipemia, gross bacterial contamination

 

Celiac Disease Antibody Test is Safe?

  • Celiac Disease Antibody Test is generally safe.
  • It's a standard blood test with minimal risks.
  • The procedure involves a needle, but discomfort is minimal.
  • Complications are rare, such as minor bruising at the puncture site.
  • Discuss any concerns with your healthcare provider.

 

When Do You Get Celiac Disease Antibody Test Results? 

  • Celiac Disease Antibody Test results are typically available within a few business days.
  • The exact reporting time may vary depending on the laboratory and healthcare provider.
  • You can usually expect to receive the results promptly for further evaluation.

 

Celiac Disease Antibody Test Limitation

Here is the basic limitation of Celiac Disease Antibody Test.

  • False negatives may occur, especially in early disease stages.
  • Results can be affected by gluten intake before testing.
  • IgA deficiency can lead to false negatives in IgA-based tests.
  • Further tests or biopsies may be needed for conclusive diagnosis.
  • Results may not identify non-celiac gluten sensitivity.

 

Celiac Disease Antibody Test Risk Factors

Here are some of the risk factors of the Celiac Disease Antibody Test.

  • Family history of celiac disease increases risk.
  • Certain genetic markers (HLA-DQ2.5, HLA-DQ8) indicate susceptibility.
  • Autoimmune disorders, like type 1 diabetes, raise the risk.
  • Gastrointestinal symptoms, anemia, or unexplained weight loss are risk factors.
  • Being of European descent or female increases susceptibility.

 

Doctor Recommendations After Celiac Disease Antibody Test Result

 Here are the Doctor's recommendations or consult a specialist after the Celiac Disease Antibody Test.

Test Result Doctor to Visit Reason
Positive Gastroenterologist Confirm and manage celiac disease.
Negative Discuss with GP Explore other potential causes.

 

Celiac Disease Antibody Test Price

Here are the estimated Celiac Disease Antibody Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

2500-5500

New Delhi

2600-5200

Bangalore

2500-5500

Hyderabad

2600-5200

Kolkata

2500-5500

Pune

2600-5200

Lucknow

2500-5500

Noida

2600-5200

Surat

2600-5200

Gurugram

2500-5500

Patna

2600-5200

Chennai

2500-5500

Jaipur

2600-5200

Ahmedabad

2500-5500

*Prices are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall, The Celiac Disease Antibody Test aids in diagnosing celiac disease, detecting gluten sensitivity, and guiding treatment decisions through blood-based antibody assessment. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • Anti-transglutaminase antibodies - Wikipedia [1].
  • Celiac Disease Tests - NIDDK [2].
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Celiac Disease Antibody Test FAQ

What is a Celiac Disease Antibody Test?

A Celiac Disease Antibody Test is a blood test used to diagnose or screen for Celiac Disease, an autoimmune condition triggered by gluten consumption. It measures specific antibodies produced by the immune system in response to gluten exposure.

How is the Celiac Disease Antibody Test performed?

The test involves a simple blood draw, where a healthcare provider collects a small sample of your blood. The blood is then analyzed in a laboratory to detect the presence of specific antibodies associated with Celiac Disease. Results are usually available within a few days.

Why is the Celiac Disease Antibody Test important?

This test plays a crucial role in diagnosing Celiac Disease, which can be challenging due to its wide range of symptoms. Early diagnosis is essential to prevent complications and initiate a gluten-free diet, the primary treatment for the condition.

What is the cost of the Celiac Disease Antibody Test?

The cost may vary depending on factors like location, healthcare provider, and insurance coverage. On average, it can range from $50 to $200. Check with your insurance provider for coverage details.

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