Cardiolipin Antibodies Test For Lupus Diagnosis

Cardiolipin Antibodies Test For Lupus Diagnosis

A cardiolipin antibodies test is a blood test that checks for specific antibodies related to autoimmune disorders like lupus or antiphospholipid syndrome. Elevated levels of these antibodies can indicate an increased risk of blood clots and other health complications.

 

Cardiolipin Antibodies Test

Here are the basic details of the Cardiolipin Antibodies Test.

Also Known As ACA (Anticardiolipin Antibodies) Test
Type Blood Test
Purpose To detect the presence of cardiolipin antibodies for lupus
Sample Type Blood (serum or plasma)
Preparation No special preparation required
Fasting Fasting is not necessary
Gender All
Age Group All
Normal Value Negative
Reporting Time 1-3 days
Cost 500-1000 INR*

*Price range may vary as per location, lab type, and procedure of lab test.

 

Cardiolipin Antibodies Test Means

The cardiolipin antibodies test checks for specific antibodies in the blood.

  • It is primarily used to diagnose autoimmune disorders like antiphospholipid syndrome.
  • Antiphospholipid syndrome can cause abnormal blood clotting and pregnancy complications.
  • Elevated cardiolipin antibodies may indicate an increased risk of thrombosis (blood clots).
  • The test helps guide treatment and management for individuals with autoimmune conditions.

 

Cardiolipin Antibodies Test Purpose

The purpose of the Cardiolipin Antibodies Test is to:

  • To detect cardiolipin antibodies in the blood.
  • Used primarily to diagnose antiphospholipid syndrome (APS).
  • APS can lead to abnormal blood clotting and pregnancy complications.
  • Helps assess the risk of thrombosis (blood clots) in individuals.
  • Guides treatment and management for autoimmune conditions.

Cardiolipin Antibodies Test Price, Normal Range, Result, Purpose, Meaning and Interpretation - Drlogy Test

 

Cardiolipin Antibodies Test Preparation

Here is the basic preparation for the Cardiolipin Antibodies Test.

 

Before Test

  • No specific preparation is typically needed.
  • Inform your healthcare provider about any medications or medical conditions.

 

During Test

  • A blood sample is collected by a healthcare professional.
  • Be cooperative and follow the provider's instructions.
  • Stay relaxed during the procedure to ensure accurate results.

 

After Test

  • Results are usually available within a few days.
  • Discuss the results with your healthcare provider for interpretation.
  • If positive, additional tests and evaluations may be needed to diagnose underlying conditions.
  • Follow any treatment recommendations or lifestyle changes provided by your healthcare provider

 

Cardiolipin Antibodies Test Procedure

Here is the basic Cardiolipin Antibodies Test Procedure.

  • Blood sample collection through a needle.
  • Centrifuge to separate serum (liquid part) from cells.
  • Mix serum with cardiolipin antigen.
  • Incubate to allow antibody-antigen reactions.
  • Wash to remove unbound substances.
  • Add detection reagents for antibody detection.
  • Incubate again for detection reactions.
  • Wash to remove excess reagents.
  • Analyze for presence and levels of cardiolipin antibodies

 

Cardiolipin Antibodies Test Result

  • Positive result: Indicates the presence of cardiolipin antibodies, suggesting an autoimmune or related disorder.
  • Negative result: Suggests no detectable cardiolipin antibodies at the time of testing.
  • Interpretation by a healthcare provider: The results should be interpreted by a healthcare professional to understand their implications and potential next steps.

Consult healthcare regardless of the result, and consult a healthcare professional for further guidance and interpretation, especially if symptomatic or with known autoimmune conditions.

 

 

Cardiolipin Antibodies Test Report

 

Cardiolipin Antibodies Test Report PDF

 

Cardiolipin Antibodies Test Normal Result

Here is the normal result of the Cardiolipin Antibodies Test.

Cardiolipin Antibodies Normal Result
IgM Cardiolipin Antibodies Negative or very low
IgG Cardiolipin Antibodies Negative or very low

The normal result indicates the absence or minimal levels of cardiolipin antibodies, suggesting no evidence of an autoimmune or related disorder associated with elevated cardiolipin antibody levels.

 

Cardiolipin Antibodies Test Interpretation

Here is the Interpretation of the Cardiolipin Antibodies Test.

Cardiolipin Antibodies Interpretation
IgM Cardiolipin Antibodies Presence suggests recent or current autoimmune or related disorders.
IgG Cardiolipin Antibodies Presence suggests past exposure to autoimmune or related disorders.
Both IgM and IgG Presence of both indicates an active autoimmune or related disorder. Further evaluation is needed.
Negative No detectable cardiolipin antibodies at the time of testing.

 

Cardiolipin Antibodies Test Positive Results

Here are potential causes of a positive cardiolipin antibody test result:

Cause Description
Autoimmune Disorders Presence of cardiolipin antibodies may indicate an autoimmune disorder, such as lupus or antiphospholipid syndrome.
Infections Some infections can trigger the production of cardiolipin antibodies in the body.
Medications Certain medications can induce the production of cardiolipin antibodies.
Other Health Conditions Various health conditions can lead to elevated cardiolipin antibody levels.

A positive result in a cardiolipin antibodies test may suggest an autoimmune disorder, ongoing or past infections, medication effects, or other health conditions.

 

Cardiolipin Antibodies Test Negative Results

Here are potential causes of a negative cardiolipin antibodies test result:

Cause Description
Absence of Autoimmune Disorders Lack of cardiolipin antibodies suggests no autoimmune disorders related to cardiolipin.
No Recent Infections Recent infections may not have triggered the production of cardiolipin antibodies.
Medication Absence The patient is not on medications that typically induce cardiolipin antibody production.
Other Health Conditions The absence of elevated cardiolipin antibodies related to health conditions.

A negative result in a cardiolipin antibodies test suggests the absence of specific autoimmune disorders, recent infections, relevant medications, or other health conditions that would trigger elevated cardiolipin antibody levels.

 

Specimen Requirements For Cardiolipin Antibodies Test

Here are the specimen requirements for the Cardiolipin Antibodies Test.

Specimen

Serum

Volume

1 ml

Container

Red-top tube or gel-barrier tube

Collection

Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.

Storage

Refrigerate or freeze.

Sample Stability

Temperature

Period

Room temperature

7 day

Refrigerated

14 days

Frozen

60 days

Freeze/thaw cycles

Stable x1

Causes for Rejection

Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types

 

Cardiolipin Antibodies Test is Safe?

Cardiolipin antibodies tests are typically safe.

  • They involve a standard blood draw, a commonly performed procedure.
  • Risks and side effects are rare but may include minor discomfort or bruising at the needle site.

 

When Do You Get Cardiolipin Antibodies Test Results? 

  • Cardiolipin antibodies test results are usually available within a few days to a week.
  • The exact time frame can vary depending on the laboratory and testing facilities.

 

Cardiolipin Antibodies Test Limitation

Here is the basic limitation of Cardiolipin Antibodies Test.

  • A positive cardiolipin antibodies test does not confirm a diagnosis on its own; it may indicate an increased risk but needs further evaluation.
  • False-positive results can occur, especially in older individuals or those with certain medical conditions.
  • Cardiolipin antibodies can fluctuate in the blood, making it challenging to rely on a single test for diagnosis.
  • Interpretation can be complex, requiring clinical context and additional testing for antiphospholipid syndrome diagnosis.
  • Test results should be considered in conjunction with other clinical and laboratory findings.

 

Cardiolipin Antibodies Test Risk Factors

Here are some of the risk factors of the Cardiolipin Antibodies Test.

  • Risk of false-positive results.
  • Fluctuating antibody levels in blood.
  • Complex interpretation and additional testing often needed.
  • Test alone doesn't confirm antiphospholipid syndrome.
  • Requires clinical context for proper evaluation.

 

Doctor Recommendations After Cardiolipin Antibodies Test Result

 Here are the Doctor's recommendations or consult a specialist after the Cardiolipin Antibodies Test.

Test Result Doctor to Visit Reason to Go
Positive Rheumatologist or Hematologist Confirm APS, further evaluation
Negative No immediate visit Follow-up as needed, if indicated

 

Cardiolipin Antibodies Test Price

Here are the estimated Cardiolipin Antibodies Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

500-1000

New Delhi

600-1000

Bangalore

500-1000

Hyderabad

600-1000

Kolkata

500-1000

Pune

600-1000

Lucknow

500-1000

Noida

600-1000

Surat

600-1000

Gurugram

500-1000

Patna

600-1000

Chennai

500-1000

Jaipur

600-1000

Ahmedabad

500-1000

*Prices are approximate and vary depending on a specific laboratory or healthcare facility.

 

 

Summary

Overall, Cardiolipin Antibodies Test aids in the diagnosis and management of antiphospholipid syndrome, assisting healthcare professionals in providing targeted care to affected individuals. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • Cardiolipin - Wikipedia [1].
  • Testing for and Clinical Significance of Anticardiolipin Antibodies - NIH [2].
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Cardiolipin Antibodies Test FAQ

What is a Cardiolipin Antibodies Test?

The Cardiolipin Antibodies Test is a blood test that measures the levels of cardiolipin antibodies in the blood, which are associated with autoimmune disorders. It helps diagnose conditions like antiphospholipid syndrome.

Why is the Cardiolipin Antibodies Test performed?

The test is done to identify autoimmune disorders, particularly antiphospholipid syndrome, and to assess the risk of blood clots and related complications.

How is the Cardiolipin Antibodies Test done?

A healthcare provider will draw a blood sample, usually from a vein in your arm, and send it to a lab for analysis.

What is the cost of the Cardiolipin Antibodies Test?

The cost of the Cardiolipin Antibodies Test typically ranges from Rs. 400 to 1200. However, it's important to note that the actual cost may vary depending on the testing facility, location, and any additional services or consultations that may be required. It's advisable to check with your healthcare provider or the specific laboratory to get the most accurate and up-to-date pricing information for the test.

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