Calprotectin Test To Detect Inflammation In The Intestines

Calprotectin Test To Detect Inflammation In The Intestines

The Calprotectin Test is a stool test to check for gut inflammation. It helps diagnose and track conditions like IBD (Inflammatory bowel disease), especially for those not in the medical field.

 

Calprotectin Test

Here are the basic details of the Calprotectin Test.

Also Known As Fecal Calprotectin Test
Type Stool Test
Purpose Detecting intestinal inflammation, monitoring IBD
Sample Type Stool (Fecal) Sample
Preparation No
Fasting Not applicable
Gender Unisex
Age Group All
Normal Value 10 to 50 or 60 μg/mg
Reporting Time Several days
Cost 2800-3800 INR*

*Price range may vary as per location, lab type, and procedure of lab test.

 

Calprotectin Test Means

Calprotectin Test is a diagnostic tool used to assess gastrointestinal inflammation.

  • It measures the level of calprotectin in stool to identify conditions like IBD.
  • Elevated levels suggest inflammation, aiding in diagnosis and monitoring.
  • The test is non-invasive, involving stool sample collection.
  • It helps healthcare providers make informed decisions about your gut health.

 

Calprotectin Test Purpose

The purpose of the Calprotectin Test is to:

  • Calprotectin Test assesses gastrointestinal inflammation.
  • Detects and monitors conditions like IBD.
  • Aids in diagnosing and tracking intestinal disorders.
  • Non-invasive, using a stool sample.
  • Provides crucial insights into gut health.

Calprotectin Test_ Price, Normal Range, Result, Purpose, Meaning and Interpretation - Drlogy Test

 

Calprotectin Test Preparation

Here is the basic preparation for the Calprotectin Test.

 

Before Test

  • No special diet or fasting is required.
  • Continue with your regular medication if applicable.
  • Collect a stool sample as instructed.

 

During Test

  • Provide a clean, uncontaminated stool sample.
  • Follow the laboratory's instructions carefully.
  • It's a straightforward, non-invasive process.

 

After Test

  • No specific post-test precautions are necessary.
  • Await the results, which may take several days.
  • Consult with your healthcare provider for result interpretation and next steps.

 

Calprotectin Test Procedure

Here is the basic Calprotectin Test Procedure.

  • Collect a stool sample in a provided container.
  • Ensure the sample is uncontaminated by urine or water.
  • Deliver the sample to the laboratory as instructed.
  • Testing is performed to measure calprotectin levels.
  • Results are typically available after several days.

 

Calprotectin Test Result

  • Elevated levels indicate likely intestinal inflammation.
  • Low levels suggest non-inflammatory conditions.
  • Moderate levels may require further investigation.

 

Calprotectin Test Normal Range

Here is the normal range of the Calprotectin Test.

Test Normal Range
Calprotectin Test 10 to 50 or 60 μg/mg

 

Calprotectin Test Interpretation

Here is the Interpretation of the Calprotectin Test.

Calprotectin Test Result Interpretation
Less than 50 μg/mg (mcg/g) No significant intestinal inflammation detected.
50 - 60 μg/mg (borderline) Mild or borderline intestinal inflammation may be present.
60 - 100 μg/mg (may be normal with some kits) Some kits may consider values up to 100 μg/mg as normal.
Above 120 μg/mg Strongly suggestive of significant intestinal inflammation.
Above 200 μg/g (positive result) Confirms the presence of inflammation; further evaluation is needed.

Calprotectin Test measures stool calprotectin levels to assess intestinal inflammation, aiding in diagnosing and monitoring conditions like IBD.

 

Calprotectin Test High Levels

Here are some possible causes of high Calprotectin levels:

Possible Causes Effects
Inflammatory Bowel Disease (IBD) Conditions like Crohn's disease and ulcerative colitis.
Gastrointestinal Infections Bacterial or parasitic infections in the digestive tract.
Colorectal Cancer Presence of cancer in the colon or rectum.
NSAID Use Use of non-steroidal anti-inflammatory drugs like ibuprofen.

High Calprotectin Test levels can be indicative of conditions such as Inflammatory Bowel Disease (IBD), gastrointestinal infections, colorectal cancer, or the use of NSAIDs.

 

Calprotectin Test Low Levels

Here are some possible causes of low Calprotectin levels:

Possible Causes Effects
Non-inflammatory Bowel Conditions Conditions like irritable bowel syndrome (IBS).
Viral Infections Viral infections in the digestive tract.
Normal Gut Health When there's no active inflammation present.

Low Calprotectin Test levels typically indicate non-inflammatory bowel conditions, viral infections, or a state of normal gut health.

 

Specimen Requirements For Calprotectin Test

Here are the specimen requirements for the Calprotectin Test.

Specimen

Stool (unpreserved, random)

Volume

1 g

Container

Clean screw-capped plastic vial

Collection

Do not contaminate outside of container; do not overfill container. Loose stools are acceptable.

Storage

Freeze.

Sample Stability

Temperature

Period

Room temperature

2 days

Refrigerated

3 days

Frozen

120 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Specimens over 72 hours old, refrigerated or thawed, or stool with urine contamination or diaper contact will be rejected.

 

Calprotectin Test is Safe?

  • Calprotectin Test is non-invasive and safe.
  • It involves a simple stool sample collection.
  • No radiation or harmful substances used.
  • It's commonly used to assess intestinal health.

 

When Do You Get Calprotectin Test Results? 

  • Results typically available in several days to one week.
  • May vary based on the testing laboratory.
  • Healthcare provider will provide result interpretation.
  • Prompt action taken for abnormal findings.

 

Calprotectin Test Limitation

Here is the basic limitation of Calprotectin Test.

  • Not a definitive diagnostic test; used in conjunction with other assessments for accurate diagnosis of gastrointestinal conditions.
  • Results can vary due to different laboratory methods and kits used.
  • Cannot pinpoint the exact location or cause of inflammation.
  • Elevated levels can be seen in conditions other than IBD, such as infections or colorectal cancer.
  • Low levels do not completely rule out underlying gut issues; additional evaluation may be needed for confirmation.

 

Calprotectin Test Risk Factors

Here are some of the risk factors of the Calprotectin Test.

  • Calprotectin test itself has minimal risk, it's non-invasive.
  • No exposure to radiation or harmful substances.
  • Risks associated with handling and transportation of stool samples, including contamination.
  • Rare potential for false-negative or false-positive results.
  • Overall, it's considered a safe diagnostic tool when proper procedures are followed.

 

Doctor Recommendations After Calprotectin Test Result

 Here are the Doctor's recommendations or consult a specialist after the Calprotectin Test.

Calprotectin Test Result Doctor to Visit Reason
High Gastroenterologist Investigate intestinal issues.
Normal General Practitioner Discuss general gut health.
Low Primary Care Physician Evaluate non-inflammatory causes.

 

Calprotectin Test Price

Here are the estimated Calprotectin Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

2800-3800

New Delhi

2000-3000

Bangalore

2800-3800

Hyderabad

2000-3000

Kolkata

2800-3800

Pune

2000-3000

Lucknow

2800-3800

Noida

2000-3000

Surat

2000-3000

Gurugram

2800-3800

Patna

2000-3000

Chennai

2800-3800

Jaipur

2000-3000

Ahmedabad

2800-3800

*Prices are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall, The Calprotectin Test assesses gut health, detecting inflammation. High levels suggest issues like IBD, while low levels indicate normal or non-inflammatory conditions. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • Calprotectin - Wikipedia [1].
  • Faecal Calprotectin - NIH [2].
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Calprotectin Test FAQ

What is a Calprotectin Test?

A Calprotectin Test is a diagnostic tool used to measure the levels of calprotectin in a patient's stool. Calprotectin is a protein found in white blood cells and is a marker for inflammation in the gastrointestinal tract.

Why is the Calprotectin Test performed?

The test is performed to help diagnose and monitor conditions such as inflammatory bowel disease (IBD), Crohn's disease, and ulcerative colitis. It aids in assessing disease activity and treatment effectiveness.

Is the Calprotectin Test painful?

No, the test is painless. It requires a small stool sample, which is collected at home or in a clinical setting, making it a non-invasive and comfortable procedure.

What do the results of the Calprotectin Test mean?

Elevated calprotectin levels may indicate intestinal inflammation. However, the results should be interpreted by a healthcare professional in the context of your medical history and symptoms.

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