BRCA Genetic Test To Check BRCA1 & BRCA2 Genes for Cancer Risk

BRCA Genetic Test is a vital tool for assessing cancer risk based on inherited gene mutations. It helps individuals make informed health decisions and understand their genetic predispositions.

BRCA Genetic Test

Here are the basic details of the BRCA Genetic Test.

*Price range may vary as per location, lab type, and procedure of lab test.

BRCA Genetic Test Means

BRCA Genetic Test, or BRCA1/BRCA2 Testing, identifies mutations in the BRCA1 and BRCA2 genes, which can increase cancer risk.

• It assesses inherited genetic variations associated with breast, ovarian, and other cancers.
• This test involves analyzing blood, saliva, or cheek cells.
• It's vital for individuals with family histories of these cancers.
• Early detection through BRCA Gene Mutation Testing enables informed decisions and personalized healthcare planning.

BRCA Genetic Test Purpose

The purpose of the BRCA Genetic Test is to:

• BRCA Gene Mutation Testing assesses the risk of breast, ovarian, and other cancers by identifying mutations in BRCA1 and BRCA2 genes.
• It empowers individuals to make informed decisions about cancer prevention.
• It helps in tailoring personalized healthcare plans based on genetic risk.
• This test aids in identifying individuals at higher risk who may benefit from enhanced screening and preventive measures.
• For individuals with a family history of these cancers, the BRCA Genetic Test provides critical information for proactive healthcare choices.

BRCA Gene Mutations and Cancer Risk

The following table illustrates how BRCA gene mutations elevate the likelihood of developing specific cancers over a lifetime:

BRCA gene mutations increase the lifetime risk of various cancers, including breast, ovarian, prostate, and pancreatic cancer.

BRCA Genetic Test Preparation

Here is the basic preparation for the BRCA Gene Mutation Testing.

Before Test

• Consult with a healthcare provider to discuss the test and its implications.
• Confirm the specific type of BRCA test (blood, saliva, or cheek swab).
• Follow any preparation instructions provided by your healthcare team.

During Test

• Follow the sample collection instructions provided by your healthcare provider or the testing kit.
• Stay relaxed and cooperate during the sample collection, which is usually quick and straightforward.

After Test

• Wait for the results, which may take several weeks.
• Schedule a follow-up appointment with your healthcare provider or genetic counselor.
• Discuss the test results and their implications for your healthcare decisions during the follow-up appointment.

BRCA Genetic Test Procedure

Here is the basic BRCA Gene Mutation Testing Procedure.

• Begin with a consultation with a healthcare provider or genetic counselor.
• Provide a blood, saliva, or cheek cell sample as directed.
• Receive and discuss results with a healthcare professional to plan appropriate healthcare actions.

BRCA Genetic Test Result

• A positive result indicates the presence of known harmful mutations, increasing cancer risk.
• A negative result means no known harmful mutations were found.
• Variants of uncertain significance (VUS) are mutations not yet associated with cancer risk; they may be reclassified later.

BRCA Genetic Test Normal Result

Here is the normal result of the BRCA Genetic Test.

BRCA Genetic Test Interpretation

Here is the Interpretation of the BRCA Gene Mutations Testing.

BRCA Genetic Test Positive Result

Here are the potential causes of BRCA Gene Mutations Positive Results.

A positive BRCA Gene Mutation Testing result indicates the presence of harmful BRCA gene mutations, increasing the risk of specific cancers.

BRCA Genetic Test Negative Result

Here are the potential causes of BRCA Mutation Negative Results.

A negative BRCA Gene Mutations result indicates the absence of harmful BRCA gene mutations, reducing the risk of specific cancers.

Specimen Requirements For BRCA Genetic Test

Here are the specimen requirements for the BRCA Genetic Test.

BRCA Genetic Test is Safe?

• Generally safe, but minor risks like bruising from blood draw.
• No significant health risks associated with the test itself.
• Focus on emotional and psychological considerations due to potential results.
• Consult with a healthcare provider for personalized guidance and support.

When Do You Get BRCA Genetic Test Results? 

• Results typically take several weeks to process.
• Time can vary depending on the laboratory and test complexity.
• Healthcare provider or genetic counselor will contact you to discuss the results.

BRCA Genetic Test Limitation

Here is the basic limitation of BRCA Gene Mutations.

• May not detect all possible mutations.
• Variants of uncertain significance may be challenging to interpret.
• Test results may not predict with certainty if you will develop cancer.
• Results are influenced by family history and other factors.
• May not provide information on other non-BRCA-related cancer risks.

BRCA Genetic Test Risk Factors

Here are some of the risk factors of the BRCA Genetic Test.

• Family history of BRCA mutations or related cancers.
• Ashkenazi Jewish heritage, higher BRCA mutation prevalence.
• Personal history of cancer.
• Young age at cancer diagnosis.
• Multiple family members with cancer.
• Specific ethnic backgrounds linked to increased BRCA risk.
• Male breast cancer history in the family.

Doctor Recommendations After BRCA Genetic Test Result

 Here are the Doctor's recommendations or consult a specialist after the BRCA Genetic Test.

BRCA Genetic Test Price

Here are the estimated BRCA Gene Mutations Prices in India with different top cities:

*Prices are approximate and vary depending on a specific laboratory or healthcare facility.

Summary

Overall, The BRCA Genetic Test assesses your risk of hereditary cancer by detecting mutations in BRCA genes, guiding personalized prevention and treatment decisions. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

Reference

• BRCA Mutation - Wikipedia [1].
• BRCA Gene Mutations: Cancer Risk and Genetic Testing - NIH [2].