Antineutrophil Cytoplasmic Antibodies (ANCA) Test checks for specific antibodies in the blood associated with autoimmune disorders like vasculitis, helping diagnose and monitor these conditions.
Here are the basic details of the ANCA Test.
Also Known As | ANCA Antibodies Test |
Type | Blood Test |
Purpose | Diagnose Autoimmune Diseases |
Sample Type | Blood |
Preparation | None |
Fasting | Not Required |
Gender | All |
Age Group | All |
Normal Value | Negative |
Reporting Time | 1-2 Days |
Cost | 1000-2000 INR* |
*Price range may vary as per location, lab type, and procedure of lab test.
ANCA Test stands for "Anti-Neutrophil Cytoplasmic Antibodies Test"
The purpose of the ANCA Test is to:
Here is the basic preparation for the ANCA Test.
Here is the basic ANCA Test Procedure.
Here's how to interpret ANCA test results in basic way.
Here is the normal range of the ANCA Test
Test Component | Normal Result |
---|---|
ANCA | Negative |
PR3 Antibodies | Absent |
MPO Antibodies | Absent |
Fluorescence | Absence of specific pattern |
Titer | Not applicable |
Here is the Interpretation of the ANCA Test.
ANCA Test Result | Interpretation |
---|---|
Positive | Supports a diagnosis of vasculitis (see details) |
Negative | Unlikely to be due to autoimmune vasculitis |
pANCA Pattern | May indicate MPO antibodies, associated with various conditions |
cANCA Pattern | May indicate PR3 antibodies, associated with specific conditions |
Atypical ANCA | Positive staining without typical pattern |
Here are the potential causes of positive ANCA test results.
Positive ANCA Test Results | Potential Causes |
---|---|
Vasculitis (Systemic Autoimmune) | Support diagnosis of autoimmune vasculitis. |
Granulomatosis with Polyangiitis (Wegener's) | Common in patients with active granulomatosis. |
Microscopic Polyangiitis | Consistent with conditions like glomerulonephritis. |
Eosinophilic Granulomatosis with Polyangiitis (Churg Strauss Syndrome) | Associated with these conditions. |
Polyarteritis Nodosa | Rare but may have positive results. |
These positive ANCA test results often support the diagnosis of autoimmune vasculitis and help distinguish between different types of vasculitis.
Here are the potential causes of negative ANCA test results which are considered normal.
Negative ANCA Test Results | Potential Causes |
---|---|
Unlikely Autoimmune Vasculitis | If symptoms suggest vasculitis, it's less likely. |
Other Health Conditions | Symptoms may be due to non-vasculitis causes. |
Timing or Remission | Cryoglobulins may not be present during the test. |
Varied Cryoglobulin Presence | Cryoglobulins can fluctuate in some disorders. |
Confirmatory Testing Needed | Negative result doesn't rule out other conditions. |
A negative ANCA test result suggests that autoimmune vasculitis is less likely, but it doesn't rule out other health conditions. Additional diagnostic tests may be needed for a comprehensive diagnosis.
Here are the specimen requirements for the ANCA Test.
Specimen |
Serum |
|
Volume |
1 ml |
|
Container |
Red-top tube or gel-barrier tube |
|
Collection |
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping. |
|
Storage |
Refrigerate or freeze. |
|
Sample Stability |
Temperature |
Period |
Room temperature |
7 days |
|
Refrigerated |
14 days |
|
Frozen |
60 days |
|
Freeze/thaw cycles |
Stable x1 |
|
Causes for Rejection |
Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types. |
ANCA (Antineutrophil Cytoplasmic Antibody) Test is generally safe.
Here is the basic limitation of ANCA Test.
Here are some of the risk factors of the ANCA Test.
Here are the Doctor's recommendations or consult a specialist after the ANCA Test.
ANCA Test Results | Doctor to Visit | Reason to Visit |
---|---|---|
Positive | Rheumatologist | Confirm vasculitis diagnosis. |
Negative | Primary Care Physician | Explore other health issues. |
Here are the estimated ANCA Test Prices in India with different top cities:
City |
Price Range (INR)* |
1000-2000 |
|
1200-2000 |
|
1000-2000 |
|
1200-2000 |
|
1000-2000 |
|
1200-2000 |
|
1000-2000 |
|
1200-2000 |
|
1200-2000 |
|
1000-2000 |
|
1200-2000 |
|
1000-2000 |
|
1200-2000 |
|
1000-2000 |
*Prices are approximate and vary depending on a specific laboratory or healthcare facility.
Summary
Overall, ANCA Test is a routine and safe blood test, aids in diagnosing autoimmune diseases and detecting conditions like vasculitis. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.
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