The Antihistone Antibodies Test is a medical tool used to detect specific antibodies related to autoimmune diseases. It helps doctors diagnose and distinguish these conditions in patients.
Here are the basic details of the Antihistone Antibodies Test.
Also Known As | Histone Antibody Test |
Type | Blood test |
Purpose | Detect autoimmune diseases and drug-induced lupus. |
Sample Type | Serum |
Preparation | No |
Fasting | Not required |
Gender | Unisex |
Age Group | All |
Normal Value | Negative |
Reporting Time | A few days |
Cost | 1000-2000 INR* |
*Antihistone Antibodies Test Price range may vary as per location, lab type, and procedure of lab test.
The Antihistone Antibodies Test is a medical examination used to detect specific antibodies related to autoimmune diseases like lupus.
The purpose of the Antihistone Antibodies Test is to:
Here is the basic preparation for the Antihistone Antibodies Test.
Here is the basic Antihistone Antibodies Test Procedure.
Here is the normal range of the Antihistone Antibodies Test.
Test | Normal Range |
---|---|
Antihistone Antibodies | < 1.0 units |
Here is the Interpretation of the Antihistone Antibodies Test.
RESULT IN Units | REMARKS |
---|---|
< 1.0 | Negative |
1.0-1.5 | Weak Positive |
1.6-2.5 | Moderate Positive |
>2.5 | Strong Positive |
Antihistone Antibodies Test interpretation varies from negative to strong positive based on unit values.
Here are potential causes of positive Antihistone Antibodies Test results:
Possible Causes | Effects |
---|---|
Autoimmune diseases (e.g., lupus, RA) | Immune system targets own tissues |
Drug-induced lupus (certain medications) | Antibodies triggered by medication exposure |
Rheumatoid arthritis (in some cases) | Elevated levels of antihistone antibodies |
Sjögren syndrome, dermatomyositis, and others | Potential symptom exacerbation |
Alzheimer's disease and dementia (association) | Research into autoimmune links |
A positive Antihistone Antibodies Test is associated with autoimmune diseases, drug-induced lupus, and potential exacerbation of symptoms.
Here are potential causes of negative Antihistone Antibodies Test results:
Possible Causes | Effects |
---|---|
Absence of autoimmune diseases or lupus | No autoimmune antibodies detected |
No exposure to medications that induce lupus | Absence of specific drug-induced antibodies |
Not having certain autoimmune conditions | Lack of evidence of these antibodies |
Healthy individuals without autoimmune issues | No autoimmune markers found in the blood |
Lack of association with Alzheimer's and dementia | No confirmed autoimmune link |
A negative Antihistone Antibodies Test indicates the absence of autoimmune markers and certain related conditions.
Here are the specimen requirements for the Antihistone Antibodies Test.
Specimen |
Serum |
|
Volume |
1 ml |
|
Container |
Red-top tube or gel-barrier tube |
|
Collection |
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping. |
|
Storage |
Room temperature |
|
Sample Stability |
Temperature |
Period |
Room temperature |
14 days |
|
Refrigerated |
14 days |
|
Frozen |
14 days |
|
Freeze/thaw cycles |
Stable x3 |
|
Causes for Rejection |
Hemolysis; icterus; lipemia; bacterial contamination |
Here is the basic limitation of Antihistone Antibodies Test.
Here are some of the risk factors of the Antihistone Antibodies Test.
Here are the Doctor's recommendations or consult a specialist after the Antihistone Antibodies Test.
Test Result | Doctor to Visit | Reason |
---|---|---|
Positive | Rheumatologist | Evaluate for treatment |
Negative | Not necessary | No significant findings |
Here are the estimated Antihistone Antibodies Test Prices in India with different top cities:
City |
Price Range (INR)* |
1000-2000 |
|
1500-2000 |
|
1000-2000 |
|
1500-2000 |
|
1000-2000 |
|
1500-2000 |
|
1000-2000 |
|
1500-2000 |
|
1500-2000 |
|
1000-2000 |
|
1500-2000 |
|
1000-2000 |
|
1500-2000 |
|
1000-2000 |
*Antihistone Antibodies Test Price are approximate and vary depending on a specific laboratory or healthcare facility.
Summary
Overall, The Antihistone Antibodies Test detects specific antibodies related to autoimmune diseases. Results guide diagnosis and treatment, helping differentiate conditions like lupus. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.
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