The Anti-dsDNA test checks for antibodies related to lupus, an autoimmune disease. It helps diagnose and monitor the condition in non-medical terms.
Here are the basic details of the Anti-dsDNA Test.
Also Known As | Anti-dsDNA Antibody Test |
Type | Blood test |
Purpose | Diagnose and monitor autoimmune disorders |
Sample Type | Serum |
Preparation | No |
Fasting | Not required |
Gender | Unisex |
Age Group | All |
Normal Value | Negative |
Reporting Time | 2-3 days |
Cost | 850-1700 INR* |
*Price range may vary as per location, lab type, and procedure of lab test.
The Anti-dsDNA Test detects antibodies against double-stranded DNA in the blood.
The purpose of the Anti-dsDNA Test is to:
Here is the basic preparation for the Anti-dsDNA Test.
Here is the basic Anti-dsDNA Test Procedure.
Here is the normal range of the Anti-dsDNA Test.
Test | Normal Range |
---|---|
Anti-dsDNA Test | Negative: <30.0 IU/mL |
Borderline: 30.0-75.0 IU/mL | |
Positive: >75.0 IU/mL |
Here is the Interpretation of the Anti-dsDNA Test.
Result | Interpretation |
---|---|
High Levels | Suggestive of lupus, especially during flare-ups. |
Very Low Levels | Typically considered negative, but not in all lupus cases. |
Moderate Levels | May be seen in other autoimmune disorders. |
Anti-dsDNA Test high levels often indicate lupus, very low levels are typically negative, while moderate levels can be linked to other autoimmune disorders.
Here are some possible causes of high Anti-dsDNA levels:
Possible Causes | Effects |
---|---|
Systemic Lupus Erythematosus (SLE) | Strong association with lupus, especially during flare-ups. |
Lupus Nephritis | Associated with ongoing kidney inflammation and damage in lupus. |
Autoimmune Disorders | Can sometimes indicate other autoimmune conditions. |
High levels of anti-dsDNA in the blood are primarily caused by systemic lupus erythematosus (SLE), lupus nephritis, or other autoimmune disorders.
Here are some possible causes of low Anti-dsDNA levels:
Cause | Effects |
---|---|
Medications, Remission | Reduced risk of lupus flares. |
Early Lupus, Certain Cancers | Low dsDNA levels, less diagnostic of lupus. |
Potential False Negative Results | Limited diagnostic accuracy for lupus. |
Low Anti-dsDNA levels can result from medications, remission, early lupus, or certain cancers, potentially leading to false-negative test results for lupus.
Here are the specimen requirements for the Anti-dsDNA Test.
Specimen |
Serum |
|
Volume |
1 ml |
|
Container |
Red-top tube or gel-barrier tube |
|
Storage |
Room temperature |
|
Sample Stability |
Temperature |
Period |
Room temperature |
14 days |
|
Refrigerated |
14 days |
|
Frozen |
14 days |
|
Freeze/thaw cycles |
Stable x3 |
|
Causes for Rejection |
Hemolysis; icterus; lipemia; bacterial contamination. |
Here is the basic limitation of Anti-dsDNA Test.
Here are some of the risk factors of the Anti-dsDNA Test.
Here are the Doctor's recommendations or consult a specialist after the Anti-dsDNA Test.
Test Result | Doctor to Consult | Reason |
---|---|---|
High | Rheumatologist | Potential lupus evaluation. |
Normal | Primary Care Physician | Regular health monitoring. |
Low | May not need a visit | Further evaluation if symptomatic. |
Here are the estimated Anti-dsDNA Test Prices in India with different top cities:
City |
Price Range (INR)* |
800-1700 |
|
800-1700 |
|
850-1700 |
|
800-1700 |
|
800-1700 |
|
800-1700 |
|
850-1700 |
|
800-1700 |
|
800-1700 |
|
850-1700 |
|
800-1700 |
|
850-1700 |
|
800-1700 |
|
850-1700 |
*Prices are approximate and vary depending on a specific laboratory or healthcare facility.
Summary
Overall, The Anti-dsDNA Test assesses anti-double-stranded DNA antibodies. High levels may indicate lupus, while low levels don't rule it out. Consult a doctor for interpretation. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.
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