Anti-DNase B Test For Rheumatic Fever and Glomerulonephritis

Anti-DNase B Test For Rheumatic Fever and Glomerulonephritis

The Anti-DNase B test helps detect antibodies produced by the body in response to a recent strep infection, aiding in the diagnosis of complications such as rheumatic fever and glomerulonephritis. It's used to confirm these conditions after a strep infection.

 

Anti-DNase B Test

Here are the basic details of the Anti-DNase B Test.

Also Known As DNase B Antibody Test
Type Blood Test
Purpose Detect Streptococcal Infections
Sample Type Blood
Preparation None
Fasting Not Required
Gender All
Age Group All
Normal Value Negative
Reporting Time Within 24 hrs
Cost 800 - 1600 INR*

*Price range may vary as per location, lab type, and procedure of lab test.

 

Anti-DNase B Test Means

Anti-DNase B Test checks for anti-DNase B antibodies.

  • It assesses the body's immune response to streptococcal infections.
  • The test uses a blood sample for analysis.
  • Generally, no fasting or special preparation is required.
  • It helps diagnose recent or past streptococcal infections, especially in cases like rheumatic fever.

 

Anti-DNase B Test Purpose

The purpose of the Anti-DNase B Test is to:

  • Detect streptococcal infections.
  • Assess immune response to streptococci.
  • Aid in diagnosing past or recent infections.
  • Monitor the risk of complications, like rheumatic fever.
  • Guide treatment and preventive measures.

Anti-DNase B Test Price, Normal Range, Result, Purpose, Procedure Meaning and Interpretation - Drlogy Test

 

Anti-DNase B Test Preparation

Here is the basic preparation for the Anti-DNase B Test.

 

Before Test

  • No special dietary restrictions or fasting are usually necessary.
  • Inform your healthcare provider about any medications or supplements you are taking.
  • Share your medical history and recent illnesses with your doctor.

 

During Test

  • A healthcare professional will draw a blood sample from a vein in your arm.
  • You may experience a brief needle prick or mild discomfort during the blood draw.

 

After Test

  • You can typically resume normal activities immediately.
  • If you experience any unusual symptoms, bleeding, or pain at the blood draw site, contact your healthcare provider.
  • Await the test results, which your doctor will discuss with you during a follow-up appointment

 

Anti-DNase B Test Procedure

Here is the basic Anti-DNase B Test Procedure.

  • A healthcare provider collects a blood sample.
  • The blood sample is usually drawn from a vein in your arm.
  • The blood sample is sent to a laboratory for analysis.
  • In the lab, technicians measure the level of anti-DNase B antibodies.
  • Results are reported as a specific numerical value.
  • Your doctor will interpret the results and discuss them with you during a follow-up appointment.

 

Anti-DNase B Test Result

Here is the basic meaning of Anti-DNase B and ASO Test Result.

  • Negative Results: Unlikely to have had a recent strep infection, especially if confirmed by additional negative tests taken 10-14 days later.
  • Positive or Elevated Results: Suggest a recent strep infection, especially if titers are rising or elevated.
  • Possible Complications: In some cases, individuals with strep-related complications may not have elevated ASO titers but could have elevated anti-DNase B titers.
  • Confirmation of Diagnosis: Elevated anti-DNase B and ASO titers can help confirm diagnoses of conditions like rheumatic fever or glomerulonephritis.

 

Anti-DNase B Test Normal Range

Here is the normal range of the Anti-DNase B Test

Normal Result Meaning
Negative Unlikely recent strep infection; further testing may be needed to confirm the diagnosis.

 

Anti-DNase B Test Interpretation

Here is the Interpretation of the Anti-DNase B Test.

Anti-DNase B Test Result Interpretation
Negative Unlikely recent strep infection; further testing may be needed to confirm diagnosis.
Positive, Elevated or Rising Likely recent strep infection, especially if accompanied by clinical symptoms of strep-related complications.

 

Anti-DNase B Test Elevated Results

Here are potential causes of elevated results on the Anti-DNase B test.

Potential Causes Explanation
Recent Streptococcal Infection Elevated levels are often due to recent or ongoing streptococcal infections, such as strep throat.
Rheumatic Fever A complication of untreated streptococcal infections, rheumatic fever can lead to increased Anti-DNase B levels.
Glomerulonephritis Certain kidney diseases, like post-streptococcal glomerulonephritis, may cause elevated Anti-DNase B.
Past Streptococcal Infection Elevated levels can persist for some time after a streptococcal infection has resolved.
Autoimmune Conditions Conditions like lupus can lead to elevated Anti-DNase B levels, though it's less common.
Monitoring Treatment Progress In some cases, the test may be used to monitor the effectiveness of treatment for streptococcal infections.

Elevated Anti-DNase B levels are primarily associated with recent or ongoing streptococcal infections and their complications, but other factors may also contribute to elevated results. Further evaluation is needed to determine the specific cause in individual cases.

 

Anti-DNase B Test Negative Results

Here are potential causes of negative results on the Anti-DNase B test.

Potential Causes Explanation
No Recent Streptococcal Infection A negative result may occur when there is no recent or ongoing streptococcal infection.
Timing of Testing The test may not detect antibodies if it's performed at a time when antibody levels are low or after they have declined following an infection.
Different Antibody Testing Negative Anti-DNase B results don't rule out other antibodies or markers that could be associated with different infections or autoimmune conditions.
Lack of Autoimmune Disease Some individuals may not have autoimmune conditions or infections associated with Anti-DNase B antibodies.

A negative Anti-DNase B test result suggests the absence of elevated Anti-DNase B antibodies, which are typically associated with recent streptococcal infections or their complications. However, a diagnosis should not rely solely on this test, and clinical evaluation is necessary to consider other factors and potential medical conditions.

 

Specimen Requirements For Anti-DNase B Test

Here are the specimen requirements for the Anti-DNase B Test.

Specimen

Serum

Volume

1 ml

Container

Red-top tube or gel-barrier tube

Collection

Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.

Storage

Room temperature

Sample Stability

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Gross hemolysis; lipemia.

 

Anti-DNase B Test is Safe?

The Anti-DNase B Test is generally safe.

  • It involves a routine blood draw, which poses minimal risks.
  • Possible side effects are limited to temporary discomfort or bruising at the blood draw site.

 

When Do You Get Anti-DNase B Test Results? 

  • Anti-DNase B Test results are generally available within 24 hrs.
  • Your healthcare provider will discuss the results with you during a follow-up appointment.

 

Anti-DNase B Test Limitation

Here is the basic limitation of Anti-DNase B Test.

  • Detects only anti-DNase B antibodies.
  • Does not confirm an active infection.
  • Interpretation may require additional tests and clinical context.

 

Anti-DNase B Test Risk Factors

Here are some of the risk factors of the Anti-DNase B Test.

  • Minimal risk associated with the Anti-DNase B Test.
  • Routine blood draw, generally safe.
  • Rare instances of temporary bruising or infection at the blood draw site.

 

Doctor Recommendations After Anti-DNase B Test Result

 Here are the Doctor's recommendations or consult a specialist after the Anti-DNase B Test.

Anti-DNase B Test Results Doctor to Visit Reason to See Doctor
Positive Infectious Disease Evaluate streptococcal infection or complications.
Negative Not applicable No specific doctor visit indicated.

 

Anti-DNase B Test Price

Here are the estimated Anti-DNase B Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

800-1600

New Delhi

900-1600

Bangalore

800-1600

Hyderabad

900-1600

Kolkata

800-1600

Pune

900-1600

Lucknow

800-1600

Noida

900-1600

Surat

900-1600

Gurugram

800-1600

Patna

900-1600

Chennai

800-1600

Jaipur

900-1600

Ahmedabad

800-1600

*Prices are approximate and vary depending on a specific laboratory or healthcare facility.

 

 

Summary

Overall, Anti-DNase B Test is a safe blood test that aids in diagnosing streptococcal infections and monitoring the risk of complications like rheumatic fever. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • Anti-DNase B Test - Wikipedia [1].
  • Anti-DNase B Test - NIH [2].
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Anti-DNase B Test FAQ

What is an Anti-DNase B Test?

The Anti-DNase B Test is a blood test used to detect elevated levels of anti-DNase B antibodies, which indicate a recent streptococcal infection.

How is the Anti-DNase B Test performed?

A blood sample is drawn from a vein, and the serum is tested for anti-DNase B antibodies. Results help determine if the patient had a recent streptococcal infection.

When should one consider an Anti-DNase B Test?

If a patient shows symptoms of strep throat, such as sore throat, fever, or joint pain, and there's a need to confirm a recent infection.

How long does it take to get Anti-DNase B Test results?

Results typically come back within a few days. The time may vary depending on the lab's workload and location.

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