Angiotensin-Converting Enzyme (ACE) Test For Blood Pressure

Angiotensin-Converting Enzyme (ACE) Test For Blood Pressure

The Angiotensin Converting Enzyme (ACE) Test is a medical analysis that assesses the level of ACE in your blood. ACE is an enzyme that plays a role in regulating blood pressure and can be a marker for certain medical conditions, particularly sarcoidosis. This test helps diagnose and monitor such conditions, providing valuable information for medical treatment.

 

ACE Test

Here are the basic details of the ACE Test.

Also Known As ACE Enzyme Test
Type Blood Enzyme Test
Purpose Aid in diagnosing certain conditions
Sample Type Blood
Preparation None
Fasting Fasting not required
Gender Any
Age Group Any
Normal Value < 40 nmol/mL/min
Reporting Time Few Days
Cost 500-1000 INR*

*ACE Test Price range may vary as per location, lab type, and procedure of lab test.

 

ACE Test Means

The Angiotensin Converting Enzyme (ACE) Test measures the level of ACE enzyme in the blood.

  • ACE is primarily associated with the renin-angiotensin system and regulates blood pressure.
  • This test is used to diagnose and monitor certain medical conditions, including sarcoidosis.
  • Sarcoidosis is a disease that can affect multiple organs, and elevated ACE levels may be indicative of its presence.
  • The ACE test assists healthcare professionals in evaluating the activity and severity of such conditions.
  • It plays a crucial role in determining appropriate treatment strategies and disease management.

 

ACE Test Purpose

The purpose of the ACE Test is to:

  • Determine ACE enzyme levels in the blood.
  • Aid in diagnosing conditions like sarcoidosis.
  • Assess enzyme activity in the body.
  • Monitor disease progression and treatment.
  • Evaluate lung and tissue disorders.

ACE Test Price, Normal Range, Result, Purpose, Procedure Meaning and Interpretation - Drlogy Test

 

ACE Test Preparation

Here is the basic preparation for the ACE Test.

 

Before Test

  • No specific fasting is usually required before the test.
  • Inform your healthcare provider of any medications or supplements you are taking.
  • Discuss any allergies or prior adverse reactions to medical procedures with your provider.

 

During Test

  • A blood sample is collected, often from a vein in your arm.
  • You may feel a brief pinprick or mild discomfort.
  • Cooperate with the technician by remaining still during the blood draw.

 

After Test

  • You can resume normal activities immediately.
  • Await the test results as advised by your healthcare provider.
  • Discuss the results and their implications with your healthcare team for any necessary follow-up or treatment.

 

ACE Test Procedure

Here is the basic ACE Test Procedure.

  • Consult with a healthcare provider for test recommendation.
  • A blood sample is collected, often from a vein.
  • The blood sample is sent to a laboratory for analysis.
  • ACE enzyme levels in the blood are measured.
  • Medical professionals interpret the results.
  • The results are discussed with the patient and guide further evaluation and treatment.

 

ACE Test Result

Here are basic meaning of Angiotensin Converting Enzyme (ACE) Test Results:

  • High ACE Levels: May suggest conditions like sarcoidosis, granulomas, or other granulomatous diseases.
  • Normal ACE Levels: Typically within the expected range, indicating no significant issues.
  • Low ACE Levels: Rarely seen and may not be clinically significant.
  • Clinical context, medical history, and other tests are important for accurate diagnosis and treatment decisions.

 

ACE Test Normal Range

Here is the normal range of the ACE Test.

Test Component Normal Range
ACE Levels < 40 nmol/mL/min

 

ACE Test Interpretation

Here is the Interpretation of the ACE Test.

Result Interpretation
High ACE Levels May suggest conditions like sarcoidosis, granulomas, or other granulomatous diseases; further evaluation needed for diagnosis.
Normal ACE Levels Typically within the expected range, but normal levels do not rule out sarcoidosis, and clinical context is crucial.
Low ACE Levels Rarely seen and may not be clinically significant; further assessment required if other symptoms or findings indicate a concern.

 

ACE Test High Levels

Here are ACE Test High Levels Potential Causes explained.

Potential Cause Explanation
Sarcoidosis Often associated with elevated ACE levels, but not exclusive to this condition.
Granulomatous Diseases Conditions like tuberculosis, histoplasmosis, or certain autoimmune disorders can lead to increased ACE levels.
Silicosis A lung disease caused by inhaling crystalline silica dust, potentially leading to elevated ACE levels.

 

ACE Test Low Levels

Here are ACE Test low levels Potential Causes explained.

Potential Cause Explanation
Medications Some drugs, like corticosteroids, may influence ACE levels and cause a decrease.
Rare Genetic Variants Extremely rare genetic variations may result in lower ACE levels.
Clinical Significance Low ACE levels may not be diagnostically significant in most cases and often require further evaluation.

 

Specimen Requirements For ACE Test

Here are the specimen requirements for the ACE Test.

Specimen

Serum

Volume

1 ml

Container

Red-top tube or gel-barrier tube

Collection

Separate serum from cells at the time of collection.

Storage

Room temperature.

Sample Stability

Temperature

Period

Room temperature

10 days

Refrigerated

10 days

Frozen

7 months

Freeze/thaw cycles

Stable x4

Causes for Rejection

Captopril, enalapril, or lisinopril administration; hemolyzed or icteric specimen;

 

ACE Test is Safe?

ACE Test is Generally safe, with minor risks.

  • Routine blood draw procedure.
  • Administered by trained healthcare providers.

 

When Do You Get ACE Test Results? 

  • ACE test results are typically available within a few days.
  • The exact reporting time may vary depending on the laboratory and specific circumstances.

 

ACE Test Limitation

Here is the basic limitation of ACE Test.

  • Elevated ACE levels not exclusive to sarcoidosis.
  • Cannot confirm the presence of granulomas.
  • Interpretation can be influenced by various factors.

 

ACE Test Risk Factors

Here are some of the risk factors of the ACE Test.

  • Low risk, involving a standard blood draw.
  • Minimal discomfort during the procedure.

 

Doctor Recommendations After ACE Test Result

 Here are the Doctor's recommendations or consult a specialist after the ACE Test.

Test Result Doctor to Visit Reason to Visit
High ACE Pulmonologist/Cardiologist Investigate potential lung issues.
Normal ACE Primary Care Physician Routine follow-up, no concerns.
Low ACE Pulmonologist/Cardiologist Monitor cardiac or lung conditions.

 

ACE Test Price

Here are the estimated ACE Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

500-1000

New Delhi

600-1000

Bangalore

500-1000

Hyderabad

600-1000

Kolkata

500-1000

Pune

600-1000

Lucknow

500-1000

Noida

600-1000

Surat

600-1000

Gurugram

500-1000

Patna

600-1000

Chennai

500-1000

Jaipur

600-1000

Ahmedabad

500-1000

*Prices are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall, ACE Test is safe for monitoring ACE levels aids in evaluating heart and lung health, promoting safety. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • ACE Test - Wikipedia [1].
  • ACE Test - NIH [2].
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ACE Test FAQ

What diseases cause high ACE levels?

Diseases such as sarcoidosis, a granulomatous inflammatory disease, and other granulomatous disorders can lead to high ACE levels. ACE is produced by cells involved in immune responses, and its levels may rise in conditions characterized by inflammation or granuloma formation.

What is normal ACE level?

Normal ACE levels vary, but a common reference range is 8 to 52 units per liter (U/L) of serum. It's essential to interpret results in the context of an individual's health and the specific reference range provided by the laboratory conducting the test.

What happen if ACE is high?

Elevated ACE levels may suggest underlying inflammation or granulomatous diseases. It doesn't diagnose a specific condition but prompts further investigation. High ACE levels can be associated with sarcoidosis, pulmonary disorders, or other inflammatory processes, indicating potential health issues that require attention.

Can ACE damage kidneys?

ACE itself doesn't directly damage kidneys. However, conditions associated with elevated ACE levels, like hypertension or inflammatory diseases, can contribute to kidney damage over time. Monitoring ACE levels helps identify potential risks to organs, enabling early intervention to prevent complications.

How can I lower my ACE levels naturally?

Lifestyle changes such as adopting a healthy diet, exercising regularly, managing stress, and avoiding smoking may support overall health, potentially impacting ACE levels indirectly. However, specific methods to directly lower ACE levels naturally are not well-established, and medical guidance is essential for managing underlying health conditions.

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