What is a Triple Marker Test?

The Triple Marker Test, also known as the Triple Screen Test or the Second Trimester Screen, is a prenatal screening test conducted during the second trimester of pregnancy.

• It involves measuring the levels of three substances in the maternal blood: alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), and estriol.
• The test helps assess the risk of certain chromosomal abnormalities, such as Down syndrome (trisomy 21) and neural tube defects, in the developing fetus.