The treatment of high VLDL (very low-density lipoprotein) cholesterol and triglycerides typically involves lifestyle changes and, in some cases, medication. Lifestyle modifications include adopting a heart-healthy diet low in refined carbohydrates, sugars, and saturated fats, while focusing on whole grains, fruits, vegetables, lean proteins, and healthy fats. Regular exercise, weight management, and quitting smoking are also important. Medications such as fibrates, niacin, and omega-3 fatty acids may be prescribed to lower VLDL levels and triglycerides, particularly if lifestyle changes are not sufficient or if there are other risk factors for cardiovascular disease. Working with a healthcare professional is crucial to determine the most appropriate treatment plan based on individual circumstances.