What is a Double Marker Test?

The Double Marker Test, also known as the Dual Marker Test or the First Trimester Screen, is a prenatal screening test conducted during the first trimester of pregnancy.

  • It is a combination of two blood tests: the measurement of serum beta-hCG (human chorionic gonadotropin) and PAPP-A (pregnancy-associated plasma protein A) levels.
  • The test helps assess the risk of chromosomal abnormalities, particularly Down syndrome (trisomy 21) and trisomy 18, in the fetus

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