Typhoid fever can present with various symptoms, and the severity can differ among individuals. Some of the worst symptoms may include sustained high fever (above 103 degrees Fahrenheit or 39.4 degrees Celsius), severe headache, abdominal pain, gastrointestinal disturbances (such as diarrhea or constipation), weakness, fatigue, and in severe cases, complications like intestinal perforation, gastrointestinal bleeding, or infection spreading to other organs. Prompt medical attention and appropriate treatment are crucial to manage the infection and prevent complications.