Progesterone to Estrogen Ratio (Pg/E2) Calculator

Progesterone to Estrogen Ratio (Pg/E2) Calculator

Progesterone to Estrogen Ratio Calculator

Result

Progesterone to Estrogen Calculator Overview

  • Progesterone to Estrogen Calculator is a tool used to calculate the ratio of progesterone to estrogen in the blood.
  • The ratio of progesterone to estrogen can provide information about the balance of hormones in the body.
  • The calculator requires two input values: progesterone level and estrogen level, which can be obtained from a blood test.
  • The calculator can be used to monitor hormonal balance during different stages of the menstrual cycle or during hormone replacement therapy.

 

What is Progesterone to Estrogen Ratio

  • Progesterone to Estrogen Ratio is a measure of the balance of two hormones, progesterone and estrogen, in the body.
  • The ratio is calculated by dividing the progesterone level by the estrogen level in the blood.
  • The Progesterone to Estrogen Ratio can provide information about the balance of hormones in the body, which can affect various aspects of health, including reproductive health.
  • A ratio greater than 200:1 suggests low estrogen levels relative to progesterone levels, while a ratio below 100:1 suggests low progesterone levels relative to estrogen levels.
  • An optimal Progesterone to Estrogen Ratio for reproductive health is considered to be between 100:1 and 200:1.
  • The ratio can be affected by various factors, including age, menstrual cycle, pregnancy, and hormone replacement therapy.

 

Steps To Calculate Progesterone to Estrogen

Here are steps to calculate the Progesterone to Estrogen Ratio.

  • Enter Progesterone Value
  • Enter Estradiol Value
  • Calculate Progesterone to Estrogen Ratio

 

Progesterone to Estrogen Formula

1. Estradiol and Progesterone Unit Conversion

  • Estradiol and progesterone are hormones that can be measured in the blood to evaluate various aspects of reproductive health.
  • The most common units of measurement for estradiol are picograms per milliliter (pg/mL) and picomoles per liter (pmol/L).
  • To convert estradiol levels from pg/mL to pmol/L, multiply the value in pg/mL by 3.671.
  • The most common units of measurement for progesterone are nanograms per milliliter (ng/mL) and nanomoles per liter (nmol/L).
  • To convert progesterone levels from ng/mL to nmol/L, multiply the value in ng/mL by 3.18.
  • Progesterone: 1 ng/mL = 3.180547 nmol/L
  • Estradiol: 1 pg/mL = 3.6713 pmol/L

 

2.  Estimation of the Progesterone to Estradiol Ratio

After bringing the hormone concentrations to the same unit of measure, the calculation of the P/E2 ratio itself is straightforward:

Ratio = progesterone / estradiol

 

Progesterone to Estrogen Normal Value

The table below summarises the normal range values for the Pg/E2 ratio and the parameters involved.

Parameter Normal range values
Progesterone (ng/mL) Pre-ovulation: <0.89
Ovulation: ≤ 12
Post-ovulation: 1.8-24
1st trimester: 11-44
2nd trimester: 25-83
3rd trimester: 58-214
Estradiol (pg/mL) Premenopausal women: 30-400
Postmenopausal women: 0-30
Pg/E2 100-500 if E2 is within the normal luteal phase range (i.e. 1.3-3.3 pg/mL in saliva or 43-180 pg/mL in blood spot)

 

How To Calculate Progesterone to Estrogen

Let's say a woman's blood test shows the following hormone levels:

  • Estradiol: 100 pg/mL
  • Progesterone: 10 ng/mL

 

To calculate the Progesterone to Estrogen ratio, you need to first convert the units of measurement for each hormone to the same units. In this example, let's convert the estradiol level from pg/mL to ng/mL:

Estradiol: 100 pg/mL = 0.1 ng/mL

 

Now that both hormones are in ng/mL, you can calculate the Progesterone to Estrogen ratio by dividing the progesterone level by the estradiol level:

  • Progesterone to Estrogen ratio = Progesterone level / Estradiol level
  • Progesterone to Estrogen ratio = 10 ng/mL / 0.1 ng/mL
  • Progesterone to Estrogen ratio = 100:1

 

In this example, the Progesterone to Estrogen ratio is 100:1.

  • This suggests that the woman has a lower level of estrogen relative to progesterone.
  • The optimal ratio for reproductive health is considered to be between 100:1 and 200:1, so the woman's ratio is within a normal range.
  • However, it's important to interpret the results in the context of the woman's medical history and other relevant factors, and to discuss the results with a healthcare professional.

 

Progesterone to Estrogen Calculator Benefits

Here are some potential benefits of using a Progesterone to Estrogen calculator:

  • Helps assess the balance between progesterone and estrogen hormones in the body.
  • Can provide insights into potential reproductive health issues, such as infertility or irregular menstrual cycles.
  • May assist in identifying hormonal imbalances that could be contributing to other symptoms, such as mood swings or fatigue.
  • Can be a useful tool for monitoring hormone levels during hormone replacement therapy or fertility treatments.
  • May provide guidance on potential lifestyle modifications or supplements that could help balance progesterone and estrogen levels, such as dietary changes or certain herbs or supplements.

 

Summary

Overall, Progesterone to Estrogen calculator is just one tool in assessing hormonal health, and should be used in conjunction with other diagnostic tools and guidance from a healthcare professional. Check More Medical Health Related Calculator on Drlogy Calculator to get exact health solution.

 

Reference

  • Progesterone - Wikipedia [1].
  • Estrogen - Wikipedia [2].
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