The calculation of the white blood cell (WBC) absolute count involves multiplying the total WBC count by the percentage of each type of white blood cell observed in the differential white blood cell count. The differential count provides the proportion of each cell type, including neutrophils, lymphocytes, monocytes, eosinophils, and basophils. To obtain the absolute count for a specific white blood cell type, multiply the total WBC count by the percentage of that cell type. For example, if the total WBC count is 10,000 cells/?L and the percentage of neutrophils is 70%, the absolute neutrophil count would be 10,000 cells/?L × 0.70 = 7,000 cells/?L. This calculation is repeated for each white blood cell type to determine their respective absolute counts. Absolute counts provide a more accurate measurement of the quantity of each cell type, aiding in the diagnosis and monitoring of various medical conditions.