| ALC Value (cells/μL) | Interpretation |
|---|---|
| <1000 | Severe lymphocytopenia (low lymphocyte count) |
| 1000 - 1500 | Mild to moderate lymphocytopenia |
| 1500 - 4000 | Normal range |
| >4000 | Mild to moderate lymphocytosis (high lymphocyte count) |
Consult Your Doctors for Further Investigation
Here are the steps to use the Absolute Lymphocyte Count Calculator:
That's it! The Absolute Lymphocyte Count Calculator is a quick and easy tool to use.
The formula for calculating the absolute lymphocyte count (ALC) is as follows:
ALC = WBC count x Lymphocytes % /100
where:
For example, if a person has a WBC count of 8,000 cells/μL and a percentage of lymphocytes of 25%, the calculation would be:
ALC = 8,000 x (25/100) ALC = 2,000 cells/μL
So, the absolute lymphocyte count, in this case, would be 2,000 cells/μL.
Here's a chart that can help you interpret the results of the Absolute Lymphocyte Count Calculator:
| ALC Value (cells/μL) | Interpretation |
|---|---|
| < 1000 | Severe lymphocytopenia (low lymphocyte count) |
| 1000 - 1500 | Mild to moderate lymphocytopenia |
| 1500 - 4000 | Normal range |
| > 4000 | Mild to moderate lymphocytosis (high lymphocyte count) |
It's important to keep in mind that the interpretation of the ALC results may depend on the individual's health status, age, and other factors. Therefore, it's always best to consult with a healthcare provider for a proper diagnosis and treatment plan.
The following table summarises the five types of WBCs and their involvement in immune function:
| WBC | Shift pattern |
| Neutrophils | Increased in bacterial infections or inflammatory disease Decreased in cancer treatment, an autoimmune disease or an infection. |
| Lymphocytes | Increased in bacterial, viral infections, leukaemia, spleen conditions, lupus or HIV infections |
| Monocytes | Increased in some leukemia |
| Eosinophils | Increased allergic reactions, skin inflammation or parasitic infections |
| Basophils | Increased in leukaemia, radiation therapy or long-term inflammation |
White blood cell differential count is one of the blood tests used in the diagnosis of conditions that affect the immune system:
Here is a table that shows the normal range of absolute lymphocyte count (ALC) based on age:
| Age Range | Normal Range for ALC |
|---|---|
| Newborns | 2500 - 8000 cells/μL |
| Infants (1-5 months) | 4000 - 10000 cells/μL |
| Children (6 months to 2 years) | 2500 - 7500 cells/μL |
| Children (2-6 years) | 1500 - 7500 cells/μL |
| Children (6-12 years) | 1500 - 6000 cells/μL |
| Adults (>12 years) | 1000 - 4000 cells/μL |
Here is a table that shows the normal range for ALC in different measurement units:
| Measurement unit | Normal range for ALC |
|---|---|
| cells/μL | 1000 - 4000 |
| cells/L | 1.0 - 4.0 |
| 10^9 cells/L | 1.0 - 4.0 |
Again, it's important to keep in mind that the interpretation of the ALC results may depend on the individual's health status, age, and other factors. Therefore, it's always best to consult with a healthcare provider for a proper diagnosis and treatment plan.
| Reason | Description |
|---|---|
| Viral infections | Certain viruses can cause a decrease in lymphocytes, such as HIV, Epstein-Barr virus, and hepatitis C virus. |
| Bacterial infections | Some bacterial infections can lead to low lymphocyte counts, including tuberculosis and brucellosis. |
| Autoimmune disorders | Autoimmune diseases such as lupus and rheumatoid arthritis can cause a reduction in lymphocytes. |
| Cancer | Certain types of cancer, such as leukemia and lymphoma, can result in low lymphocyte counts. |
| Chemotherapy | Chemotherapy drugs can affect the production of lymphocytes, leading to lower counts. |
| Radiation therapy | Radiation therapy can damage the bone marrow, where lymphocytes are produced, resulting in decreased levels. |
| Malnutrition | Poor nutrition can cause a decrease in lymphocytes due to a lack of essential vitamins and minerals. |
| Medications | Certain medications, such as corticosteroids and immunosuppressants, can lower lymphocyte counts as a side effect. |
| Inherited disorders | Rare genetic conditions, such as DiGeorge syndrome and Wiskott-Aldrich syndrome, can result in low lymphocyte levels. |
| Stress | Chronic stress can weaken the immune system and lead to a reduction in lymphocytes. |
| Viral infections | Certain viral infections can cause an increase in lymphocytes, such as infectious mononucleosis and viral hepatitis. |
| Bacterial infections | Some bacterial infections can lead to high lymphocyte counts, including pertussis, tuberculosis, and Lyme disease. |
| Autoimmune disorders | Autoimmune diseases such as multiple sclerosis and Graves' disease can cause an elevation in lymphocytes. |
| Chronic inflammation | Chronic inflammatory conditions, such as inflammatory bowel disease and rheumatoid arthritis, can result in high lymphocyte counts. |
| Cancer | Some types of cancer, such as leukemia and lymphoma, can cause an increase in lymphocytes. |
| Medications | Certain medications, such as corticosteroids and anticonvulsants, can raise lymphocyte counts as a side effect. |
| Thyroid disorders | Thyroid disorders, such as hyperthyroidism and Hashimoto's thyroiditis, can lead to high lymphocyte counts. |
| Stress | Acute stress can trigger an increase in lymphocytes as part of the body's fight-or-flight response. |
| Allergic reactions | Allergic reactions can cause an elevation in lymphocytes as part of the immune system's response to an allergen. |
| Vaccination | Vaccination can stimulate an increase in lymphocytes as part of the body's immune response to the vaccine. |
The Absolute Lymphocyte Count (ALC) Calculator offers several benefits, including:
Overall, the ALC Calculator is a valuable tool that can help healthcare providers monitor the immune system's health and provide appropriate treatment to patients. Check More Medical Health Related Calcultor on Drlogy Calculator to get exact health solution.
Reference
To calculate the absolute lymphocyte count (ALC), you need to know two things: the total white blood cell count (WBC) and the percentage of lymphocytes in the differential white blood cell count.
The formula for calculating ALC is:
ALC = WBC count × % lymphocytes/100
For example, if the WBC count is 8000 cells/μL and the percentage of lymphocytes in the differential count is 20%, then the ALC would be:
ALC = 8000 × 20/100 ALC = 1600 cells/μL
Therefore, the absolute lymphocyte count in this example is 1600 cells/μL.
It's important to note that the ALC can vary based on various factors such as age, underlying health conditions, and medication use. A healthcare provider should always interpret the ALC results in the context of the individual's overall health status.
If lymphocytes are high, it is called lymphocytosis. There are many possible reasons why lymphocytes may be high, including:
Infections: A common cause of lymphocytosis is viral infections such as infectious mononucleosis, cytomegalovirus, and hepatitis.
Chronic lymphocytic leukemia: This is a type of cancer that affects the lymphocytes, causing an overproduction of abnormal lymphocytes.
Autoimmune disorders: Some autoimmune disorders, such as lupus and rheumatoid arthritis, can cause an increase in lymphocytes.
Medications: Certain medications, such as steroids, can cause an increase in lymphocytes.
Stress: Emotional or physical stress can cause an increase in lymphocytes.
Other conditions: Other conditions such as tuberculosis, lymphoma, and HIV infection can cause an increase in lymphocytes.
It's important to note that lymphocytosis is not always a cause for concern and maybe a normal response to certain situations such as an infection. However, in some cases, lymphocytosis can indicate a more serious underlying condition. Therefore, it's always best to consult with a healthcare provider for a proper diagnosis and treatment plan.
If the absolute lymphocyte count (ALC) is low, it is called lymphocytopenia. There are many possible reasons why ALC may be low, including:
Infections: Certain viral infections such as HIV and hepatitis, as well as bacterial and fungal infections, can cause a decrease in lymphocytes.
Medications: Certain medications such as chemotherapy drugs and immunosuppressive medications can cause a decrease in lymphocytes.
Autoimmune disorders: Some autoimmune disorders, such as lupus and rheumatoid arthritis, can cause a decrease in lymphocytes.
Bone marrow disorders: Bone marrow disorders such as aplastic anemia, myelodysplastic syndrome, and leukemia can cause a decrease in lymphocytes.
Radiation therapy: Radiation therapy can cause a decrease in lymphocytes.
Other conditions: Other conditions such as malnutrition, alcoholism, and stress can cause a decrease in lymphocytes.
Lymphocytopenia can increase the risk of infections and other health complications. However, the severity of the effects of lymphocytopenia may depend on the underlying cause and the individual's health status. Therefore, it's always best to consult with a healthcare provider for a proper diagnosis and treatment plan.
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