Several diseases and conditions can cause low hemoglobin (Hb) levels, leading to anemia. Some common causes include: 1. Iron Deficiency: Inadequate iron intake, poor iron absorption, or excessive blood loss can result in iron deficiency anemia. 2. Vitamin Deficiencies: Lack of vitamin B12, folate, or other essential nutrients can contribute to anemia. 3. Chronic Kidney Disease: Impaired production of erythropoietin, a hormone involved in red blood cell production, can lead to anemia. 4. Chronic Inflammation: Conditions such as rheumatoid arthritis, lupus, or inflammatory bowel disease can affect red blood cell production and lifespan. 5. Bone Marrow Disorders: Disorders like aplastic anemia, myelodysplastic syndromes, or leukemia can impair the production of healthy blood cells. 6. Chronic Diseases: Chronic infections, cancer, or autoimmune disorders can contribute to anemia. 7. Gastrointestinal Disorders: Conditions affecting the gut, such as celiac disease or Crohn's disease, can affect nutrient absorption and contribute to anemia. It's important to consult with a healthcare professional to determine the underlying cause of low Hb and develop an appropriate treatment plan. Proper diagnosis and management of the underlying condition are crucial for improving Hb levels and overall health.