What is the Anti-Saccharomyces Cerevisiae Antibody (ASCA) Test?
The Anti-Saccharomyces Cerevisiae Antibody (ASCA) Test is a blood test used to detect specific antibodies associated with Crohn's disease (CD) and ulcerative colitis (UC), which are inflammatory bowel diseases (IBD). It helps in the differential diagnosis of IBD.
How does the ASCA test work?
The ASCA test measures the levels of antibodies directed against a protein found in the cell wall of the yeast Saccharomyces cerevisiae. Elevated levels of these antibodies in the blood may indicate the presence of IBD, especially Crohn's disease.
Who should consider getting an ASCA test?
The ASCA test is typically recommended for individuals with symptoms suggestive of IBD, such as chronic diarrhea, abdominal pain, and unexplained weight loss. It can aid in the diagnosis when IBD is suspected.
What do ASCA test results indicate?
Elevated levels of ASCA antibodies may suggest a higher likelihood of IBD, particularly Crohn's disease. However, it's essential to remember that ASCA results are not definitive and should be considered in the context of a broader evaluation.